Category:GO:0000976 ! transcription regulatory region sequence-specific DNA binding

name: transcription regulatory region sequence-specific DNA binding
namespace: molecular_function
alt_id: GO:0000975
alt_id: GO:0044212
def: "Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon." [GOC:txnOH]
comment: To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.
synonym: "regulatory region DNA binding" BROAD []
synonym: "transcription regulatory region DNA binding" RELATED []
is_a: GO:0001067 ! regulatory region nucleic acid binding
is_a: GO:1990837 ! sequence-specific double-stranded DNA binding

AmiGO <GOterm>GO:0000976</GOterm>
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