MYXXD:Q1D7Q3

Species (Taxon ID)	Myxococcus xanthus (strain DK 1622). (246197)
Gene Name(s)	fruA (ECO:0000313 with EMBL:ABF92619.1)
Protein Name(s)	FruA protein (ECO:0000313 with EMBL:ABF92619.1)
External Links
UniProt	Q1D7Q3
EMBL	CP000113
RefSeq	YP_631320.1
ProteinModelPortal	Q1D7Q3
IntAct	Q1D7Q3
STRING	246197.MXAN_3117
PRIDE	Q1D7Q3
EnsemblBacteria	ABF92619
GeneID	4107313
KEGG	mxa:MXAN_3117
PATRIC	22648797
eggNOG	COG2197
OMA	CFDEGAS
OrthoDB	EOG69GZGV
BioCyc	MXAN246197:GIWU-3090-MONOMER
Proteomes	UP000002402
GO	GO:0003677 GO:0003700 GO:0000160 GO:0006351
Gene3D	1.10.10.10
InterPro	IPR011006 IPR016032 IPR001789 IPR000792 IPR011991
Pfam	PF00196 PF00072
PRINTS	PR00038
SMART	SM00421
SUPFAM	SSF46894 SSF52172
PROSITE	PS50043 PS50110

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0003677	DNA binding	PMID:PMC1539954	ECO:0000314			F		Figure 2 demonstrates an example of one gene promoter region that FruA is able to bind to. E. coli containing a plasmid with the fruA gene was used to produce sufficient quantities of protein after induction with IPTG. 2A demonstrates that FruA was only produced after IPTG induction. The protein was then used in gel-shift assays with P32-labelled DNA, as shown in 2B. The sigma-4400 promoter region, which contains the proposed FruA binding site, forms a band that indicates binding only in the presence of IPTG-induced protein; in other words, only in the presence of FruA. The right side is another gene region from M. xanthus that does not contain the proposed FruA binding site, and acts as a negative control.	complete CACAO 4217
part_of	GO:0032993	protein-DNA complex	PMID:16040607	ECO:0005634	genomic systematic evolution of ligands by exponential amplification evidence used in manual assertion	RefSeq:NC_008095.1	C		Seeded From UniProt	complete
part_of	GO:0032993	protein-DNA complex	PMID:16040607	ECO:0005631	DNAse footprinting evidence used in manual assertion	RefSeq:NC_008095.1	C		Seeded From UniProt	complete
enables	GO:0001216	DNA-binding transcription activator activity	PMID:16040607	ECO:0005634	genomic systematic evolution of ligands by exponential amplification evidence used in manual assertion	RefSeq:NC_008095.1	F		Seeded From UniProt	complete
enables	GO:0001216	DNA-binding transcription activator activity	PMID:16040607	ECO:0005631	DNAse footprinting evidence used in manual assertion	RefSeq:NC_008095.1	F		Seeded From UniProt	complete
enables	GO:0000976	transcription regulatory region sequence-specific DNA binding	PMID:16040607	ECO:0005634	genomic systematic evolution of ligands by exponential amplification evidence used in manual assertion	RefSeq:NC_008095.1	F		Seeded From UniProt	complete
enables	GO:0000976	transcription regulatory region sequence-specific DNA binding	PMID:16040607	ECO:0005631	DNAse footprinting evidence used in manual assertion	RefSeq:NC_008095.1	F		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0001216	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0001216	P		Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001789	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016032	F		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000792 InterPro:IPR016032	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
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References

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