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PSEAE:Q9HTL4
Contents
| Species (Taxon ID) | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228). (208964) | |
| Gene Name(s) | oxyR (ECO:0000313 with EMBL:AAG08729.1) | |
| Protein Name(s) | OxyR (ECO:0000313 with EMBL:AAG08729.1) | |
| External Links | ||
| UniProt | Q9HTL4 | |
| EMBL | AE004091 | |
| PIR | F82979 | |
| RefSeq | NP_254031.1 | |
| ProteinModelPortal | Q9HTL4 | |
| SMR | Q9HTL4 | |
| STRING | 208964.PA5344 | |
| DNASU | 878254 | |
| EnsemblBacteria | AAG08729 | |
| GeneID | 878254 | |
| KEGG | pae:PA5344 | |
| PATRIC | 19845547 | |
| PseudoCAP | PA5344 | |
| HOGENOM | HOG000233514 | |
| InParanoid | Q9HTL4 | |
| KO | K04761 | |
| OMA | CPEFARF | |
| OrthoDB | EOG6N6848 | |
| PhylomeDB | Q9HTL4 | |
| Proteomes | UP000002438 | |
| GO | GO:0001071 GO:0003700 GO:0044212 GO:1900377 GO:2000147 GO:0046889 GO:1901671 GO:1901031 GO:0006351 | |
| Gene3D | 1.10.10.10 | |
| InterPro | IPR005119 IPR000847 IPR011991 | |
| Pfam | PF00126 PF03466 | |
| PRINTS | PR00039 | |
| PROSITE | PS50931 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0042542 |
response to hydrogen peroxide |
ECO:0000315 |
P |
Fig. 1A (Lane 2), Fig. 1B (Lane 2) |
complete | |||||
| GO:0001071 |
nucleic acid binding transcription factor activity |
ECO:0000314 |
F |
EMSA results in figure 2 prove OxyR binds to the promoter regions of several P. aerugenosa genes. Additionally, figure 3 shows that expression of dps, pvdS and trxB2 genes increased in the presence of OxyR activated by H2O2. |
complete | |||||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0005631 |
DNAse footprinting evidence used in manual assertion |
RefSeq:NC_008463.1 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0005620 |
chromatin immunoprecipitation-PCR evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0001807 |
electrophoretic mobility shift assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032993 |
protein-DNA complex |
ECO:0006007 |
chromatin immunoprecipitation-chip evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032993 |
protein-DNA complex |
ECO:0005631 |
DNAse footprinting evidence used in manual assertion |
RefSeq:NC_008463.1 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0032993 |
protein-DNA complex |
ECO:0005620 |
chromatin immunoprecipitation-PCR evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032993 |
protein-DNA complex |
ECO:0001807 |
electrophoretic mobility shift assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032993 |
protein-DNA complex |
ECO:0001807 |
electrophoretic mobility shift assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032993 |
protein-DNA complex |
ECO:0001807 |
electrophoretic mobility shift assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0001808 |
reverse transcription polymerase chain reaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001216 |
DNA-binding transcription activator activity |
ECO:0001807 |
electrophoretic mobility shift assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000976 |
transcription regulatory region sequence-specific DNA binding |
ECO:0006007 |
chromatin immunoprecipitation-chip evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000976 |
transcription regulatory region sequence-specific DNA binding |
ECO:0001807 |
electrophoretic mobility shift assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000976 |
transcription regulatory region sequence-specific DNA binding |
ECO:0001807 |
electrophoretic mobility shift assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:2000147 |
positive regulation of cell motility |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901671 |
positive regulation of superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901031 |
regulation of response to reactive oxygen species |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1900377 |
negative regulation of secondary metabolite biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046889 |
positive regulation of lipid biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0044212 |
transcription regulatory region DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045893 |
positive regulation of transcription, DNA-templated |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0001216 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Panmanee, W & Hassett, DJ (2009) Differential roles of OxyR-controlled antioxidant enzymes alkyl hydroperoxide reductase (AhpCF) and catalase (KatB) in the protection of Pseudomonas aeruginosa against hydrogen peroxide in biofilm vs. planktonic culture. FEMS Microbiol. Lett. 295 238-44 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Wei, Q et al. (2012) Global regulation of gene expression by OxyR in an important human opportunistic pathogen. Nucleic Acids Res. 40 4320-33 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Heo, YJ et al. (2010) The major catalase gene (katA) of Pseudomonas aeruginosa PA14 is under both positive and negative control of the global transactivator OxyR in response to hydrogen peroxide. J. Bacteriol. 192 381-90 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Ochsner, UA et al. (2000) Role of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF. J. Bacteriol. 182 4533-44 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Vinckx, T et al. (2010) The Pseudomonas aeruginosa oxidative stress regulator OxyR influences production of pyocyanin and rhamnolipids: protective role of pyocyanin. Microbiology (Reading, Engl.) 156 678-86 PubMed GONUTS page
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- GO:0046889 ! positive regulation of lipid biosynthetic process
- GO:2000147 ! positive regulation of cell motility
- GO:1901671 ! positive regulation of superoxide dismutase activity
- GO:0045893 ! positive regulation of DNA-templated transcription
- GO:0032993 ! protein-DNA complex
- Proteobacteria
- Pseudomonadaceae
- Pseudomonadales
- Pseudomonas
- Pseudomonas aeruginosa
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