CHICK:HDAC1

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	HDAC1 (synonyms: HDAC1A)
Protein Name(s)	Histone deacetylase 1 HD1
External Links
UniProt	P56517
EMBL	AF039751 AF043328 AF044169
RefSeq	NP_989487.1
UniGene	Gga.10603
ProteinModelPortal	P56517
BioGrid	675010
STRING	9031.ENSGALP00000005212
PaxDb	P56517
PRIDE	P56517
Ensembl	ENSGALT00000005221
GeneID	373961
KEGG	gga:373961
CTD	3065
eggNOG	COG0123
GeneTree	ENSGT00530000062889
HOGENOM	HOG000225180
HOVERGEN	HBG057112
InParanoid	P56517
KO	K06067
OMA	HASCVKF
OrthoDB	EOG7DNNTW
PhylomeDB	P56517
TreeFam	TF106171
BRENDA	3.5.1.98
Reactome	REACT_271785 REACT_282783 REACT_286472 REACT_311887 REACT_320040 REACT_320742 REACT_326801 REACT_340836 REACT_344213
NextBio	20813492
PRO	PR:P56517
Proteomes	UP000000539
GO	GO:0005737 GO:0005829 GO:0000118 GO:0005634 GO:0016581 GO:0016580 GO:0001047 GO:0004407 GO:0032041 GO:0000978 GO:0000980 GO:0001106 GO:0008134 GO:0043044 GO:0016568 GO:0070933 GO:0043922 GO:0060766 GO:0008284 GO:0010870 GO:0045944 GO:0006351
Gene3D	3.40.800.20
InterPro	IPR000286 IPR003084 IPR023801
PANTHER	PTHR10625
Pfam	PF00850
PIRSF	PIRSF037913
PRINTS	PR01270 PR01271

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0070933	histone H4 deacetylation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:108086 MGI:MGI:1097691 MGI:MGI:1343091 PANTHER:PTN002578320 PomBase:SPAC3G9.07c SGD:S000005274 SGD:S000006272 UniProtKB:G5EB64 UniProtKB:Q13547	P	Seeded From UniProt	complete
involved_in	GO:0070932	histone H3 deacetylation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:108086 MGI:MGI:1097691 PANTHER:PTN002578320 RGD:1309799 RGD:619976 RGD:619977 SGD:S000005274 TAIR:locus:2098115 UniProtKB:G5EB64 UniProtKB:Q13547	P	Seeded From UniProt	complete
part_of	GO:0070822	Sin3-type complex	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015805 PANTHER:PTN000066122 PomBase:SPBC36.05c SGD:S000005274 UniProtKB:Q13547 UniProtKB:Q92769	C	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002578320 PomBase:SPBC36.05c SGD:S000005274 SGD:S000006272 UniProtKB:O15379 UniProtKB:Q13547 UniProtKB:Q92769 WB:WBGene00001834	P	Seeded From UniProt	complete
enables	GO:0004407	histone deacetylase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015805 FB:FBgn0025825 MGI:MGI:108086 MGI:MGI:1097691 PANTHER:PTN002578320 PomBase:SPAC3G9.07c PomBase:SPBC36.05c RGD:1309799 RGD:619976 SGD:S000003162 SGD:S000005274 TAIR:locus:2162017 UniProtKB:G5EB64 UniProtKB:O15379 UniProtKB:Q13547 UniProtKB:Q7K6A1 UniProtKB:Q92769 WB:WBGene00001834 dictyBase:DDB_G0270338	F	Seeded From UniProt	complete
part_of	GO:0000118	histone deacetylase complex	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015805 MGI:MGI:108086 PANTHER:PTN002578320 PomBase:SPAC3G9.07c PomBase:SPBC36.05c SGD:S000003162 SGD:S000005274 SGD:S000006272 UniProtKB:Q13547 UniProtKB:Q92769 WB:WBGene00001834	C	Seeded From UniProt	complete
involved_in	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
enables	GO:1990841	promoter-specific chromatin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
involved_in	GO:0090090	negative regulation of canonical Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0070933	histone H4 deacetylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0070932	histone H3 deacetylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
enables	GO:0070888	E-box binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
involved_in	GO:0061198	fungiform papilla formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0061029	eyelid development in camera-type eye	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0048714	positive regulation of oligodendrocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	C	Seeded From UniProt	complete
involved_in	GO:0042733	embryonic digit morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
enables	GO:0035851	Krueppel-associated box domain binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	C	Seeded From UniProt	complete
involved_in	GO:0032922	circadian regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0021766	hippocampus development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
enables	GO:0019213	deacetylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
part_of	GO:0017053	transcriptional repressor complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	C	Seeded From UniProt	complete
part_of	GO:0016581	NuRD complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	C	Seeded From UniProt	complete
involved_in	GO:0009913	epidermal cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
involved_in	GO:0007623	circadian rhythm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
involved_in	GO:0007492	endoderm development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	C	Seeded From UniProt	complete
enables	GO:0004407	histone deacetylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
enables	GO:0003714	transcription corepressor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
enables	GO:0001103	RNA polymerase II repressing transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
enables	GO:0000976	transcription regulatory region sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	F	Seeded From UniProt	complete
part_of	GO:0000792	heterochromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	C	Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	C	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	P	Seeded From UniProt	complete
part_of	GO:0000118	histone deacetylase complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O09106 ensembl:ENSMUSP00000099657	C	Seeded From UniProt	complete
involved_in	GO:0090090	negative regulation of canonical Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
involved_in	GO:0070933	histone H4 deacetylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
involved_in	GO:0070932	histone H3 deacetylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
enables	GO:0070491	repressing transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
involved_in	GO:0060766	negative regulation of androgen receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
involved_in	GO:0052548	regulation of endopeptidase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
enables	GO:0051059	NF-kappaB binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
enables	GO:0047485	protein N-terminus binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
involved_in	GO:0043922	negative regulation by host of viral transcription	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
enables	GO:0042826	histone deacetylase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
enables	GO:0033613	activating transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
enables	GO:0033558	protein deacetylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	C	Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
part_of	GO:0016581	NuRD complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	C	Seeded From UniProt	complete
part_of	GO:0016580	Sin3 complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	C	Seeded From UniProt	complete
involved_in	GO:0016575	histone deacetylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
involved_in	GO:0010870	positive regulation of receptor biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
involved_in	GO:0006476	protein deacetylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
involved_in	GO:0006357	regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
involved_in	GO:0006346	methylation-dependent chromatin silencing	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	C	Seeded From UniProt	complete
enables	GO:0004407	histone deacetylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
enables	GO:0003714	transcription corepressor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
enables	GO:0002039	p53 binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
enables	GO:0001103	RNA polymerase II repressing transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
enables	GO:0001085	RNA polymerase II transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
enables	GO:0001046	core promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
enables	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	C	Seeded From UniProt	complete
part_of	GO:0000785	chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	C	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13547 ensembl:ENSP00000362649	P	Seeded From UniProt	complete
enables	GO:0051059	NF-kappaB binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q6IT96 ensembl:ENSP00000362649	F	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q6IT96 ensembl:ENSP00000362649	C	Seeded From UniProt	complete
enables	GO:0004407	histone deacetylase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003084	F	Seeded From UniProt	complete
involved_in	GO:0016575	histone deacetylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003084	P	Seeded From UniProt	complete
enables	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.5.1.98	F	Seeded From UniProt	complete
enables	GO:0004407	histone deacetylase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.5.1.98	F	Seeded From UniProt	complete
involved_in	GO:0006325	chromatin organization	PMID:12711221^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:12711221^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:12711221^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:12711221^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0004407	histone deacetylase activity	PMID:12711221^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0000118	histone deacetylase complex	PMID:12711221^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
involved_in	GO:0006325	chromatin organization	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0156	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Verdin, E et al. (2003) Class II histone deacetylases: versatile regulators. Trends Genet. 19 286-93 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:12711221-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Verdin, E et al. (2003) Class II histone deacetylases: versatile regulators. Trends Genet. 19 286-93 PubMed GONUTS page

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