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Category:GO:0016581 ! NuRD complex
name: NuRD complex
namespace: cellular_component
def: "An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins." [PMID:10589671, PMID:11743021, PMID:17289569]
synonym: "Mi-2 complex" NARROW []
synonym: "NRD complex" EXACT []
synonym: "nucleosome remodeling and histone deacetylation complex" EXACT []
is_a: GO:0000118 ! histone deacetylase complex
is_a: GO:0005667 ! transcription regulator complex
is_a: GO:0090545 ! CHD-type complex
AmiGO
<GOterm>GO:0016581</GOterm>
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