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MOUSE:MTA3

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Mta3
Protein Name(s) Metastasis-associated protein MTA3
External Links
UniProt Q924K8
EMBL AF288138
BC022124
CCDS CCDS28997.1
RefSeq NP_001164525.1
NP_473423.1
UniGene Mm.277668
Mm.443827
PDB 2CRG
PDBsum 2CRG
ProteinModelPortal Q924K8
SMR Q924K8
BioGrid 228046
IntAct Q924K8
MINT MINT-4102500
PhosphoSite Q924K8
MaxQB Q924K8
PaxDb Q924K8
PRIDE Q924K8
DNASU 116871
Ensembl ENSMUST00000067826
GeneID 116871
KEGG mmu:116871
UCSC uc012axw.1
CTD 57504
MGI MGI:2151172
eggNOG NOG252834
GeneTree ENSGT00580000081398
HOGENOM HOG000045387
HOVERGEN HBG002598
InParanoid Q924K8
KO K11660
OMA HMSRQAT
PhylomeDB Q924K8
TreeFam TF106444
Reactome REACT_235780
REACT_257106
EvolutionaryTrace Q924K8
NextBio 369242
PRO PR:Q924K8
Proteomes UP000000589
Bgee Q924K8
CleanEx MM_MTA3
ExpressionAtlas Q924K8
Genevestigator Q924K8
GO GO:0008278
GO:0005737
GO:0005634
GO:0016581
GO:0003682
GO:0043565
GO:0003700
GO:0008270
GO:0008284
GO:0010971
InterPro IPR001025
IPR000949
IPR009057
IPR001005
IPR017884
IPR000679
Pfam PF01426
PF01448
PF00320
SMART SM00439
SM00717
SM00401
SUPFAM SSF46689
PROSITE PS51038
PS51156
PS51293

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0042826

histone deacetylase binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001328846
RGD:1306743
UniProtKB:Q8N108
UniProtKB:Q8N344

F

Seeded From UniProt

complete

part_of

GO:0016581

NuRD complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1346340
MGI:MGI:2150037
PANTHER:PTN000852793
UniProtKB:A0A0B4KG70
UniProtKB:O94776

C

Seeded From UniProt

complete

involved_in

GO:0016575

histone deacetylation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001328846
UniProtKB:Q7Z3K6
UniProtKB:Q8N108
UniProtKB:Q8N344

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001328846
UniProtKB:O94776
UniProtKB:Q13330
UniProtKB:Q7Z3K6
UniProtKB:Q8N108

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1346340
MGI:MGI:2150037
MGI:MGI:2151172
PANTHER:PTN001328846
RGD:1306743
RGD:621018
UniProtKB:Q13330
UniProtKB:Q7Z3K6
UniProtKB:Q8N108
UniProtKB:Q8N344
UniProtKB:Q9BTC8

C

Seeded From UniProt

complete

enables

GO:0003714

transcription corepressor activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001328846
UniProtKB:Q13330

F

Seeded From UniProt

complete

enables

GO:0003713

transcription coactivator activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2150037
PANTHER:PTN000852793
UniProtKB:Q13330

F

Seeded From UniProt

complete

enables

GO:0001103

RNA polymerase II repressing transcription factor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001328846
UniProtKB:O94776
UniProtKB:Q13330

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1346340
PANTHER:PTN001328846

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045892

negative regulation of transcription, DNA-templated

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9BTC8

P

Seeded From UniProt

complete

enables

GO:0044877

protein-containing complex binding

PMID:22075476[2]

ECO:0000314

direct assay evidence used in manual assertion

F

  • occurs_in:(EMAPA:17962)
  • has_input:(GO:0008278)|has_input:(GO:0016581)
  • occurs_in:(CL:0000501)
  • occurs_in:(EMAPA:35633)

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9BTC8

C

Seeded From UniProt

complete

part_of

GO:0016581

NuRD complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9BTC8

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010971

positive regulation of G2/M transition of mitotic cell cycle

PMID:22075476[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

  • regulates_o_occurs_in:(EMAPA:17962)
  • regulates_o_occurs_in:(CL:0000501)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0008284

positive regulation of cell population proliferation

PMID:22075476[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:11483358[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:22770845[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:22075476[2]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:35633)
  • part_of:(CL:0000501)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:20720167[5]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:16033)
  • part_of:(CL:0000007)|part_of:(EMAPA:16036)
  • part_of:(CL:0000007)|part_of:(EMAPA:16037)
  • part_of:(CL:0000007)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:11483358[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9BTC8

C

Seeded From UniProt

complete

involved_in

GO:1903508

positive regulation of nucleic acid-templated transcription

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0003713

P

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BTC8
ensembl:ENSP00000385823

P

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BTC8
ensembl:ENSP00000385823

C

Seeded From UniProt

complete

part_of

GO:0016581

NuRD complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BTC8
ensembl:ENSP00000385823

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BTC8
ensembl:ENSP00000385823

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009057

F

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001025

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000679

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000679

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000679

F

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-NUL-573385
Reactome:R-NUL-573373

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 Kwintkiewicz, J et al. (2012) Metastasis-associated protein 3 (MTA3) regulates G2/M progression in proliferating mouse granulosa cells. Biol. Reprod. 86 1-8 PubMed GONUTS page
  3. ↑ 3.0 3.1 Simpson, A et al. (2001) Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3. Gene 273 29-39 PubMed GONUTS page
  4. ↑ Qin, J et al. (2012) The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development. Cell Stem Cell 11 319-32 PubMed GONUTS page
  5. ↑ Ma, P et al. (2010) Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development. Biol. Reprod. 83 1027-35 PubMed GONUTS page
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