Category:GO:0004407 ! histone deacetylase activity

id: GO:0004407

name: histone deacetylase activity
namespace: molecular_function
def: "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes." [EC:3.5.1.98, PMID:9893272]
xref: EC:3.5.1.98
xref: MetaCyc:3.5.1.98-RXN
xref: RHEA:58196
is_a: GO:0016811 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
is_a: GO:0033558 ! protein deacetylase activity
relationship: part_of: GO:0016575 ! histone deacetylation

AmiGO <GOterm>GO:0004407</GOterm>
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