HUMAN:SOX11

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	SOX11
Protein Name(s)	Transcription factor SOX-11
External Links
UniProt	P35716
EMBL	U23752 AB028641 AC108025 X73038
CCDS	CCDS1654.1
PIR	G01758 S34118
RefSeq	NP_003099.1
UniGene	Hs.432638
ProteinModelPortal	P35716
SMR	P35716
STRING	9606.ENSP00000322568
PhosphoSite	P35716
DMDM	1351142
MaxQB	P35716
PaxDb	P35716
PRIDE	P35716
DNASU	6664
Ensembl	ENST00000322002
GeneID	6664
KEGG	hsa:6664
UCSC	uc002qyj.3
CTD	6664
GeneCards	GC02P005842
HGNC	HGNC:11191
HPA	CAB009378 CAB056152 HPA000536
MIM	600898 615866
neXtProt	NX_P35716
Orphanet	1465
PharmGKB	PA36028
eggNOG	NOG130659
GeneTree	ENSGT00760000118988
HOGENOM	HOG000231874
HOVERGEN	HBG005040
InParanoid	P35716
KO	K09268
OMA	NPDWCKT
OrthoDB	EOG7TMZVP
PhylomeDB	P35716
TreeFam	TF351735
ChiTaRS	SOX11
GeneWiki	SOX11
GenomeRNAi	6664
NextBio	25981
PRO	PR:P35716
Proteomes	UP000005640
Bgee	P35716
CleanEx	HS_SOX11
ExpressionAtlas	P35716
Genevestigator	P35716
GO	GO:0005737 GO:0005634 GO:0001158 GO:0001077 GO:0000979 GO:0001105 GO:0003700 GO:0000976 GO:0008135 GO:0003211 GO:0061386 GO:0061303 GO:0048557 GO:0048704 GO:0061029 GO:0021782 GO:0014009 GO:0060022 GO:0001822 GO:0002089 GO:0060174 GO:0060425 GO:0060548 GO:0010629 GO:0060253 GO:0050672 GO:0000122 GO:2000678 GO:0014032 GO:0001841 GO:0060563 GO:0030182 GO:0003357 GO:0014003 GO:0003151 GO:0030513 GO:0008284 GO:0010628 GO:0035332 GO:0046887 GO:2001111 GO:0050769 GO:0045666 GO:0045778 GO:0045669 GO:2000648 GO:0045944 GO:0045893 GO:0017015 GO:0072395 GO:0035914 GO:0001501 GO:0060023 GO:0061053 GO:0021510 GO:0048485 GO:0006412 GO:0060412
Gene3D	1.10.30.10
InterPro	IPR009071 IPR029551 IPR017386
PANTHER	PTHR10270:SF113
Pfam	PF00505
PIRSF	PIRSF038098
SMART	SM00398
SUPFAM	SSF47095
PROSITE	PS50118

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:19274049^[1]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:19274049^[1]	ECO:0000255	match to sequence model evidence used in manual assertion	InterPro:IPR009071 InterPro:IPR017386	F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GO_REF:0000113	ECO:0005556	multiple sequence alignment evidence used in manual assertion	UniProtKB:Q04890	F		Seeded From UniProt	complete
involved_in	GO:2001111	positive regulation of lens epithelial cell proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:2000678	negative regulation of transcription regulatory region DNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P0C1G9	P		Seeded From UniProt	complete
involved_in	GO:2000648	positive regulation of stem cell proliferation	PMID:20626275^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0072395	signal transduction involved in cell cycle checkpoint	PMID:20624318^[3]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061386	closure of optic fissure	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0061303	cornea development in camera-type eye	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0061053	somite development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0061029	eyelid development in camera-type eye	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0060563	neuroepithelial cell differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0060548	negative regulation of cell death	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0060425	lung morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0060412	ventricular septum morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0060253	negative regulation of glial cell proliferation	PMID:19808959^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060174	limb bud formation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0060023	soft palate development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0060022	hard palate development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0050769	positive regulation of neurogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0050672	negative regulation of lymphocyte proliferation	PMID:20624318^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048704	embryonic skeletal system morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0048557	embryonic digestive tract morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0048485	sympathetic nervous system development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0046887	positive regulation of hormone secretion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21124928^[5]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(UniProtKB:Q53H47)\|has_regulation_target:(UniProtKB:Q16643)\|has_regulation_target:(UniProtKB:Q9Y5L2)	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0045778	positive regulation of ossification	PMID:20626275^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045669	positive regulation of osteoblast differentiation	PMID:20626275^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	PMID:19808959^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035332	positive regulation of hippo signaling	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0030513	positive regulation of BMP signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:10574465^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0021782	glial cell development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0021510	spinal cord development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	PMID:20624318^[3]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0014032	neural crest cell development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0014009	glial cell proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	PMID:19808959^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	PMID:19808959^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:17934069^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:17934069^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0003357	noradrenergic neuron differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0003211	cardiac ventricle formation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0003151	outflow tract morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0002089	lens morphogenesis in camera-type eye	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0001841	neural tube formation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
involved_in	GO:0001501	skeletal system development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	P		Seeded From UniProt	complete
enables	GO:0001158	enhancer sequence-specific DNA binding	PMID:19808959^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	F		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	F	occurs_at:(SO:0001952)	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:21124928^[5]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(UniProtKB:Q53H47)\|has_direct_input:(UniProtKB:Q16643)\|has_direct_input:(UniProtKB:Q9Y5L2)	Seeded From UniProt	complete
enables	GO:0000976	transcription regulatory region sequence-specific DNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P0C1G9	F		Seeded From UniProt	complete
enables	GO:0000976	transcription regulatory region sequence-specific DNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7M6Y2	F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:19808959^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98359 PANTHER:PTN001616003 RGD:69351 UniProtKB:P35716	P		Seeded From UniProt	complete
part_of	GO:0044798	nuclear transcription factor complex	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103559 MGI:MGI:107543 MGI:MGI:98362 MGI:MGI:98363 MGI:MGI:98364 MGI:MGI:98366 MGI:MGI:98660 PANTHER:PTN000030384	C		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001616003 UniProtKB:P35716	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98363 PANTHER:PTN000030384	P		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103559 MGI:MGI:107543 MGI:MGI:2654070 MGI:MGI:98364 PANTHER:PTN000030384 UniProtKB:P48431 UniProtKB:Q06945	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000411 FB:FBgn0005612 FB:FBgn0005613 FB:FBgn0029123 FB:FBgn0036411 MGI:MGI:103559 MGI:MGI:107543 MGI:MGI:98357 MGI:MGI:98359 MGI:MGI:98363 MGI:MGI:98364 MGI:MGI:98366 MGI:MGI:98369 MGI:MGI:98660 PANTHER:PTN000030384 RGD:1565646 RGD:3759 RGD:69351 UniProtKB:P35713 UniProtKB:P35716 UniProtKB:P48430 UniProtKB:P48431 UniProtKB:Q05066 UniProtKB:Q06945 UniProtKB:Q9BT81 UniProtKB:Q9H6I2 WB:WBGene00004771	C		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103559 MGI:MGI:107543 MGI:MGI:98362 MGI:MGI:98363 MGI:MGI:98364 MGI:MGI:98366 MGI:MGI:98660 PANTHER:PTN000030384 ZFIN:ZDB-GENE-990715-6	F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98359 PANTHER:PTN001616003 UniProtKB:P35716	P		Seeded From UniProt	complete
involved_in	GO:2000678	negative regulation of transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
involved_in	GO:0014003	oligodendrocyte development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	C		Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	F		Seeded From UniProt	complete
involved_in	GO:0003357	noradrenergic neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
involved_in	GO:0001822	kidney development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	F		Seeded From UniProt	complete
enables	GO:0000976	transcription regulatory region sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	F		Seeded From UniProt	complete
involved_in	GO:2001111	positive regulation of lens epithelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0061386	closure of optic fissure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0061303	cornea development in camera-type eye	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0061053	somite development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0061029	eyelid development in camera-type eye	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0060563	neuroepithelial cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0060548	negative regulation of cell death	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0060425	lung morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0060412	ventricular septum morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0060253	negative regulation of glial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0060174	limb bud formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0060023	soft palate development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0060022	hard palate development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0050769	positive regulation of neurogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0048704	embryonic skeletal system morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0048557	embryonic digestive tract morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0048485	sympathetic nervous system development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0046887	positive regulation of hormone secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0045778	positive regulation of ossification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0035914	skeletal muscle cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0035332	positive regulation of hippo signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0030513	positive regulation of BMP signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0021782	glial cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0021510	spinal cord development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0014032	neural crest cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0014009	glial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	C		Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	F		Seeded From UniProt	complete
involved_in	GO:0003357	noradrenergic neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0003211	cardiac ventricle formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0003151	outflow tract morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0002089	lens morphogenesis in camera-type eye	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0001841	neural tube formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
involved_in	GO:0001501	skeletal system development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	F		Seeded From UniProt	complete
enables	GO:0001158	enhancer sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	F		Seeded From UniProt	complete
enables	GO:0000976	transcription regulatory region sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q7M6Y2 ensembl:ENSMUSP00000078070	P		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR029551	F		Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0524	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Larson, BL et al. (2010) Sox11 is expressed in early progenitor human multipotent stromal cells and decreases with extensive expansion of the cells. Tissue Eng Part A 16 3385-94 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 Gustavsson, E et al. (2010) SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies. Mol. Cancer 9 187 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Hide, T et al. (2009) Sox11 prevents tumorigenesis of glioma-initiating cells by inducing neuronal differentiation. Cancer Res. 69 7953-9 PubMed GONUTS page
↑ ^5.0 ^5.1 Wang, X et al. (2010) Gene expression profiling and chromatin immunoprecipitation identify DBN1, SETMAR and HIG2 as direct targets of SOX11 in mantle cell lymphoma. PLoS ONE 5 e14085 PubMed GONUTS page
↑ Azuma, T et al. (1999) Human SOX11, an upregulated gene during the neural differentiation, has a long 3' untranslated region. DNA Res. 6 357-60 PubMed GONUTS page
↑ ^7.0 ^7.1 Ek, S et al. (2008) Nuclear expression of the non B-cell lineage Sox11 transcription factor identifies mantle cell lymphoma. Blood 111 800-5 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 ^8.6 ^8.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:19274049-1] 1.0 ^1.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page

[PMID:20626275-2] 2.0 ^2.1 ^2.2 Larson, BL et al. (2010) Sox11 is expressed in early progenitor human multipotent stromal cells and decreases with extensive expansion of the cells. Tissue Eng Part A 16 3385-94 PubMed GONUTS page

[PMID:20624318-3] 3.0 ^3.1 ^3.2 Gustavsson, E et al. (2010) SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies. Mol. Cancer 9 187 PubMed GONUTS page

[PMID:19808959-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Hide, T et al. (2009) Sox11 prevents tumorigenesis of glioma-initiating cells by inducing neuronal differentiation. Cancer Res. 69 7953-9 PubMed GONUTS page

[PMID:21124928-5] 5.0 ^5.1 Wang, X et al. (2010) Gene expression profiling and chromatin immunoprecipitation identify DBN1, SETMAR and HIG2 as direct targets of SOX11 in mantle cell lymphoma. PLoS ONE 5 e14085 PubMed GONUTS page

[PMID:10574465-6] Azuma, T et al. (1999) Human SOX11, an upregulated gene during the neural differentiation, has a long 3' untranslated region. DNA Res. 6 357-60 PubMed GONUTS page

[PMID:17934069-7] 7.0 ^7.1 Ek, S et al. (2008) Nuclear expression of the non B-cell lineage Sox11 transcription factor identifies mantle cell lymphoma. Blood 111 800-5 PubMed GONUTS page

[PMID:21873635-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 ^8.6 ^8.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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