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PMID:19274049

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Citation

Vaquerizas, JM, Kummerfeld, SK, Teichmann, SA and Luscombe, NM (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10:252-63

Abstract

Transcription factors are key cellular components that control gene expression: their activities determine how cells function and respond to the environment. Currently, there is great interest in research into human transcriptional regulation. However, surprisingly little is known about these regulators themselves. For example, how many transcription factors does the human genome contain? How are they expressed in different tissues? Are they evolutionarily conserved? Here, we present an analysis of 1,391 manually curated sequence-specific DNA-binding transcription factors, their functions, genomic organization and evolutionary conservation. Much remains to be explored, but this study provides a solid foundation for future investigations to elucidate regulatory mechanisms underlying diverse mammalian biological processes.

Links

PubMed Online version:10.1038/nrg2538

Keywords

Evolution, Molecular; Gene Expression; Genome, Human; Humans; Transcription Factors/genetics; Transcription Factors/metabolism

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

HUMAN:ZN395

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SMAD1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001132
InterPro:IPR003619
InterPro:IPR013019
InterPro:IPR013790

F

Seeded From UniProt

complete

HUMAN:SMAD1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SMAD2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SMAD2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001132
InterPro:IPR003619
InterPro:IPR013019
InterPro:IPR013790

F

Seeded From UniProt

complete

HUMAN:SMAD3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001132
InterPro:IPR003619
InterPro:IPR013019
InterPro:IPR013790

F

Seeded From UniProt

complete

HUMAN:SMAD3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SMAD4

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001132
InterPro:IPR003619
InterPro:IPR013019
InterPro:IPR013790

F

Seeded From UniProt

complete

HUMAN:SMAD4

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SMAD5

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001132
InterPro:IPR003619
InterPro:IPR013019
InterPro:IPR013790

F

Seeded From UniProt

complete

HUMAN:SMAD5

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SMAD9

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001132
InterPro:IPR003619
InterPro:IPR013019
InterPro:IPR013790

F

Seeded From UniProt

complete

HUMAN:SMAD9

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:P53

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:P53

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR002117
InterPro:IPR008967
InterPro:IPR011615
InterPro:IPR012346

F

Seeded From UniProt

complete

HUMAN:SRBP1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SRBP1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:ATF1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ATF1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001630
InterPro:IPR004827

F

Seeded From UniProt

complete

HUMAN:DLX3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:DLX3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000047
InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:PO5F1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000327
InterPro:IPR001356
InterPro:IPR009057
InterPro:IPR010982
InterPro:IPR013847
InterPro:IPR015585

F

Seeded From UniProt

complete

HUMAN:PO5F1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NR1H2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NR1H2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000324
InterPro:IPR001628
InterPro:IPR001723

F

Seeded From UniProt

complete

HUMAN:PDX1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PDX1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000047
InterPro:IPR001356
InterPro:IPR001827
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:ITF2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ITF2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:TFE2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:TFE2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:FOXC1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001766

F

Seeded From UniProt

complete

HUMAN:FOXC1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NR1H3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000324
InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR001728

F

Seeded From UniProt

complete

HUMAN:NR1H3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PPARA

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PPARA

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR003074
InterPro:IPR003076

F

Seeded From UniProt

complete

HUMAN:SPDEF

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SPDEF

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000418

F

Seeded From UniProt

complete

HUMAN:TAL1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:GATA3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:GATA3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000679
InterPro:IPR016374

F

Seeded From UniProt

complete

HUMAN:NKX31

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NKX31

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:ZN143

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:TF2L1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:TF2L1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR007604

F

Seeded From UniProt

complete

HUMAN:SP2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:HIF1A

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001321
InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:HIF1A

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:EZH2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:EZH2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001005

F

Seeded From UniProt

complete

HUMAN:ELF3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000418
InterPro:IPR000637

F

Seeded From UniProt

complete

HUMAN:ELF3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:MYC

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:MYC

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR002418
InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:KLF5

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ESR2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ESR2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000324
InterPro:IPR001628
InterPro:IPR001723

F

Seeded From UniProt

complete

HUMAN:FOXO1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001766

F

Seeded From UniProt

complete

HUMAN:NSD2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR009071

F

Seeded From UniProt

complete

HUMAN:NSD2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ESR1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000324
InterPro:IPR001628
InterPro:IPR001723

F

Seeded From UniProt

complete

HUMAN:ESR1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NFKB1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000451
InterPro:IPR002909
InterPro:IPR008967
InterPro:IPR011539

F

Seeded From UniProt

complete

HUMAN:NFKB1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:P73

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:P73

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR002117
InterPro:IPR008967
InterPro:IPR011615
InterPro:IPR012346

F

Seeded From UniProt

complete

HUMAN:TCFL5

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:TCFL5

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SOX2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SOX2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR009071

F

Seeded From UniProt

complete

HUMAN:ZBT7A

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NF2L2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NF2L2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR004827
InterPro:IPR008917

F

Seeded From UniProt

complete

HUMAN:BACH1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR004827
InterPro:IPR008917

F

Seeded From UniProt

complete

HUMAN:BACH1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PPARD

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PPARD

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR003074
InterPro:IPR003075

F

Seeded From UniProt

complete

HUMAN:TYY1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:REL

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:REL

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000451
InterPro:IPR002909
InterPro:IPR008967
InterPro:IPR011539

F

Seeded From UniProt

complete

HUMAN:RELB

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:RELB

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000451
InterPro:IPR002909
InterPro:IPR008967
InterPro:IPR011539

F

Seeded From UniProt

complete

HUMAN:TF65

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:TF65

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000451
InterPro:IPR002909
InterPro:IPR008967
InterPro:IPR011539

F

Seeded From UniProt

complete

HUMAN:IRF7

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:IRF7

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001346

F

Seeded From UniProt

complete

HUMAN:WT1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:WT1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000976

F

Seeded From UniProt

complete

HUMAN:SOX9

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR009071

F

Seeded From UniProt

complete

HUMAN:SOX9

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ANDR

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000324
InterPro:IPR001103
InterPro:IPR001628
InterPro:IPR001723

F

Seeded From UniProt

complete

HUMAN:ANDR

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:HXA1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:HXA1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:P63

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:P63

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR002117
InterPro:IPR008967
InterPro:IPR011615
InterPro:IPR012346

F

Seeded From UniProt

complete

HUMAN:FOXO3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001766

F

Seeded From UniProt

complete

HUMAN:VDR

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000324
InterPro:IPR001628
InterPro:IPR001723

F

Seeded From UniProt

complete

HUMAN:VDR

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PAX9

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:PAX9

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:MITF

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:MITF

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PITX3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001356
InterPro:IPR009057
InterPro:IPR016233

F

Seeded From UniProt

complete

HUMAN:PITX3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:FOXL2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001766

F

Seeded From UniProt

complete

HUMAN:ELF1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000418

F

Seeded From UniProt

complete

HUMAN:ELF1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:CDC5L

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001005
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:CDC5L

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SOX11

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR009071
InterPro:IPR017386

F

Seeded From UniProt

complete

HUMAN:SOX11

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SNAI2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:TWST1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598
InterPro:IPR015789

F

Seeded From UniProt

complete

HUMAN:TWST1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NR5A2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000324
InterPro:IPR001628
InterPro:IPR001723

F

Seeded From UniProt

complete

HUMAN:NR5A2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ATF4

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ATF4

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR004827

F

Seeded From UniProt

complete

HUMAN:IRF6

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001346

F

Seeded From UniProt

complete

HUMAN:IRF6

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:THB

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR001728

F

Seeded From UniProt

complete

HUMAN:THB

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:DDIT3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR004827

F

Seeded From UniProt

complete

HUMAN:DDIT3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:IRF5

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:IRF5

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001346

F

Seeded From UniProt

complete

HUMAN:ASCL4

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598
InterPro:IPR015660

F

Seeded From UniProt

complete

HUMAN:ASCL4

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PHX2B

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:PHX2B

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:FOXH1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001766

F

Seeded From UniProt

complete

HUMAN:FOXH1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:FOXJ1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001766

F

Seeded From UniProt

complete

HUMAN:TBX2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:TBX2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001699
InterPro:IPR002070
InterPro:IPR008967

F

Seeded From UniProt

complete

HUMAN:SIX1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000047
InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:SIX1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NR1H4

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000324
InterPro:IPR001628
InterPro:IPR001723

F

Seeded From UniProt

complete

HUMAN:NR1H4

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PLAL2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PEBB

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR003417

F

Seeded From UniProt

complete

HUMAN:PEBB

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PPARG

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR003074
InterPro:IPR003077

F

Seeded From UniProt

complete

HUMAN:PPARG

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SNAI1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:PO3F2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000327
InterPro:IPR001356
InterPro:IPR009057
InterPro:IPR010982
InterPro:IPR013847
InterPro:IPR016362

F

Seeded From UniProt

complete

HUMAN:PO3F2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:YBOX1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR002059

F

Seeded From UniProt

complete

HUMAN:YBOX1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:GATA5

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:GATA5

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000679
InterPro:IPR016375

F

Seeded From UniProt

complete

HUMAN:MSX2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000047
InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:MSX2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:BCL6

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:LHX2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:LHX2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:KLF4

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:SOX13

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR009071

F

Seeded From UniProt

complete

HUMAN:SOX13

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ZNT9

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR009061

F

Seeded From UniProt

complete

HUMAN:THA11

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR006612

F

Seeded From UniProt

complete

HUMAN:BMAL1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001067
InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:BMAL1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:CREB1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001630
InterPro:IPR004827

F

Seeded From UniProt

complete

HUMAN:CREB1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:FOXP3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001766

F

Seeded From UniProt

complete

HUMAN:E2F1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR003316
InterPro:IPR015633

F

Seeded From UniProt

complete

HUMAN:E2F1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:FOSL1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR004827

F

Seeded From UniProt

complete

HUMAN:FOSL1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:JUN

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR002112
InterPro:IPR004827
InterPro:IPR008917
InterPro:IPR015558

F

Seeded From UniProt

complete

HUMAN:JUN

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:LHX6

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:LHX6

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:FOXM1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001766

F

Seeded From UniProt

complete

HUMAN:FOXM1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:HSF1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000232

F

Seeded From UniProt

complete

HUMAN:HSF1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:TERF2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001005
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:CDX1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000047
InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:CDX1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ZEB1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001356

F

Seeded From UniProt

complete

HUMAN:ZEB1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ZEB2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001356

F

Seeded From UniProt

complete

HUMAN:ZEB2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:FOSL2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR004827

F

Seeded From UniProt

complete

HUMAN:FOSL2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:TBX3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:TBX3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001699
InterPro:IPR002070
InterPro:IPR008967

F

Seeded From UniProt

complete

HUMAN:GLI3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:IKZF1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:FOXC2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001766

F

Seeded From UniProt

complete

HUMAN:MNX1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:E4F1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:KMT2A

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000637

F

Seeded From UniProt

complete

HUMAN:PO4F2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR000327
InterPro:IPR001356
InterPro:IPR009057
InterPro:IPR010982
InterPro:IPR013847
InterPro:IPR015584

F

Seeded From UniProt

complete

HUMAN:PO4F2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:MEIS1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001356
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:MEIS1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ID2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:ID2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:KMT2D

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR009071

F

Seeded From UniProt

complete

HUMAN:IRF3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001346

F

Seeded From UniProt

complete

HUMAN:IRF3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:OLIG1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:OLIG1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ID1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:ID1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:STAT3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:STAT3

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001217
InterPro:IPR008967
InterPro:IPR012345
InterPro:IPR013801

F

Seeded From UniProt

complete

HUMAN:SRBP2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR011598

F

Seeded From UniProt

complete

HUMAN:SRBP2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:DNJC2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001005
InterPro:IPR009057

F

Seeded From UniProt

complete

HUMAN:TFDP1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR003316
InterPro:IPR015648

F

Seeded From UniProt

complete

HUMAN:TFDP1

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:ZN281

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NFYA

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

HUMAN:NFYA

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000255: match to sequence model evidence used in manual assertion

InterPro:IPR001289

F

Seeded From UniProt

complete

HUMAN:KLF2

enables

GO:0000981: DNA-binding transcription factor activity, RNA polymerase II-specific

ECO:0000303: author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

Notes

See also

References

See Help:References for how to manage references in GONUTS.