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PSEAE:Q9HV73

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Species (Taxon ID) Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228). (208964)
Gene Name(s) cbrB (ECO:0000313 with EMBL:AAG08112.1)
Protein Name(s) Two-component response regulator CbrB (ECO:0000313 with EMBL:AAG08112.1)
External Links
UniProt Q9HV73
EMBL AE004091
PIR C83055
RefSeq NP_253414.1
ProteinModelPortal Q9HV73
SMR Q9HV73
STRING 208964.PA4726
EnsemblBacteria AAG08112
GeneID 881609
KEGG pae:PA4726
PATRIC 19844233
PseudoCAP PA4726
HOGENOM HOG000058489
InParanoid Q9HV73
OMA LENSMER
PhylomeDB Q9HV73
Proteomes UP000002438
GO GO:0005524
GO:0003677
GO:0000160
GO:2000147
GO:2001158
GO:1900081
GO:0090368
GO:0006355
GO:0006351
Gene3D 3.40.50.300
InterPro IPR003593
IPR011006
IPR027417
IPR001789
IPR002078
IPR025662
IPR025943
IPR025944
Pfam PF00072
PF00158
SMART SM00382
SM00448
SUPFAM SSF52172
SSF52540
PROSITE PS50110
PS00675
PS00676
PS00688
PS50045

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004565

beta-galactosidase activity

PMID:21478360[1]

ECO:0000315

F

Fig 2B lane 2 shows that the mutant cbrB results in zero beta-galactosidase activity.

complete
CACAO 4958

part_of

GO:0032993

protein-DNA complex

PMID:21478360[1]

ECO:0005667

site-directed mutagenesis phenotypic evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0032993

protein-DNA complex

PMID:21478360[1]

ECO:0001807

electrophoretic mobility shift assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0001216

DNA-binding transcription activator activity

PMID:21478360[1]

ECO:0005667

site-directed mutagenesis phenotypic evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0001216

DNA-binding transcription activator activity

PMID:21478360[1]

ECO:0001807

electrophoretic mobility shift assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:21478360[1]

ECO:0005667

site-directed mutagenesis phenotypic evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:21478360[1]

ECO:0001807

electrophoretic mobility shift assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:2001158

positive regulation of proline catabolic process to glutamate

PMID:11401699[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000147

positive regulation of cell motility

PMID:21169488[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1900081

regulation of arginine catabolic process

PMID:11401699[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0090368

regulation of ornithine metabolic process

PMID:11401699[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0001216

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0001216

P

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001789

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002078

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002078

P

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002078

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Abdou, L et al. (2011) Promoter recognition and activation by the global response regulator CbrB in Pseudomonas aeruginosa. J. Bacteriol. 193 2784-92 PubMed GONUTS page
  2. 2.0 2.1 2.2 Nishijyo, T et al. (2001) The CbrA-CbrB two-component regulatory system controls the utilization of multiple carbon and nitrogen sources in Pseudomonas aeruginosa. Mol. Microbiol. 40 917-31 PubMed GONUTS page
  3. Yeung, AT et al. (2011) The sensor kinase CbrA is a global regulator that modulates metabolism, virulence, and antibiotic resistance in Pseudomonas aeruginosa. J. Bacteriol. 193 918-31 PubMed GONUTS page