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ECOLI:ARAC

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) araC
Protein Name(s) Arabinose operon regulatory protein
External Links
UniProt P0A9E0
EMBL V00256
V00259
J01641
U00096
AP009048
K01303
PIR A91473
RefSeq NP_414606.1
YP_488370.1
PDB 1XJA
2AAC
2ARA
2ARC
2K9S
PDBsum 1XJA
2AAC
2ARA
2ARC
2K9S
ProteinModelPortal P0A9E0
SMR P0A9E0
DIP DIP-9125N
IntAct P0A9E0
STRING 511145.b0064
EnsemblBacteria AAC73175
BAB96633
GeneID 12931834
944780
KEGG ecj:Y75_p0064
eco:b0064
PATRIC 32115229
EchoBASE EB0052
EcoGene EG10054
eggNOG COG2207
HOGENOM HOG000276603
InParanoid P0A9E0
KO K02099
OMA FYCNPGD
OrthoDB EOG6K3ZZH
PhylomeDB P0A9E0
BioCyc EcoCyc:PD00242
ECOL316407:JW0063-MONOMER
EvolutionaryTrace P0A9E0
PRO PR:P0A9E0
Proteomes UP000000318
UP000000625
Genevestigator P0A9E0
GO GO:0005737
GO:0043565
GO:0003700
GO:0019568
GO:0006351
Gene3D 1.10.10.60
2.60.120.280
InterPro IPR003313
IPR009057
IPR018060
IPR018062
IPR020449
Pfam PF02311
PF12833
PRINTS PR00032
SMART SM00342
SUPFAM SSF46689
SSF51215
PROSITE PS00041
PS01124

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0032993

protein-DNA complex

PMID:24272778[1]

ECO:0005667

site-directed mutagenesis phenotypic evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0001217

DNA-binding transcription repressor activity

PMID:24272778[1]

ECO:0005667

site-directed mutagenesis phenotypic evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:24272778[1]

ECO:0005667

site-directed mutagenesis phenotypic evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:9103202[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0A9E0

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:24561554[3]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0A9E0

F

Seeded From UniProt

complete

involved_in

GO:0019568

arabinose catabolic process

PMID:13829634[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0001217

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009057

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018060
InterPro:IPR018062
InterPro:IPR020449

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003313
InterPro:IPR018060
InterPro:IPR018062
InterPro:IPR020449

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018060
InterPro:IPR018062

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0019568

arabinose catabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0054

P

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0119

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Stringer, AM et al. (2014) Genome-scale analyses of Escherichia coli and Salmonella enterica AraC reveal noncanonical targets and an expanded core regulon. J. Bacteriol. 196 660-71 PubMed GONUTS page
  2. Soisson, SM et al. (1997) Structural basis for ligand-regulated oligomerization of AraC. Science 276 421-5 PubMed GONUTS page
  3. Rajagopala, SV et al. (2014) The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. 32 285-90 PubMed GONUTS page
  4. GROSS, J & ENGLESBERG, E (1959) Determination of the order of mutational sites governing L-arabinose utilization in Escherichia coli B/r bv transduction with phage Plbt. Virology 9 314-31 PubMed GONUTS page
  5. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page