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PSEAE:Q9HXI7
Contents
| Species (Taxon ID) | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228). (208964) | |
| Gene Name(s) | iscR (ECO:0000313 with EMBL:AAG07202.1) | |
| Protein Name(s) | IscR (ECO:0000313 with EMBL:AAG07202.1) | |
| External Links | ||
| UniProt | Q9HXI7 | |
| EMBL | AE004091 | |
| PIR | H83168 | |
| RefSeq | NP_252504.1 | |
| ProteinModelPortal | Q9HXI7 | |
| SMR | Q9HXI7 | |
| STRING | 208964.PA3815 | |
| DNASU | 879919 | |
| EnsemblBacteria | AAG07202 | |
| GeneID | 879919 | |
| KEGG | pae:PA3815 | |
| PATRIC | 19842273 | |
| PseudoCAP | PA3815 | |
| HOGENOM | HOG000249812 | |
| InParanoid | Q9HXI7 | |
| KO | K13643 | |
| OMA | RCMTHDL | |
| OrthoDB | EOG63FW56 | |
| PhylomeDB | Q9HXI7 | |
| Proteomes | UP000002438 | |
| GO | GO:0003690 GO:0003700 | |
| Gene3D | 1.10.10.10 | |
| InterPro | IPR010242 IPR000944 IPR011991 | |
| Pfam | PF02082 | |
| TIGRFAMs | TIGR02010 TIGR00738 | |
| PROSITE | PS51197 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0005653 |
northern assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0001808 |
reverse transcription polymerase chain reaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032993 |
protein-DNA complex |
ECO:0001807 |
electrophoretic mobility shift assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001217 |
DNA-binding transcription repressor activity |
ECO:0001807 |
electrophoretic mobility shift assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
| GO:0006979 |
response to oxidative stress |
ECO:0000315 |
P |
Figure 5 shows decreased survival under oxidative stress conditions in an iscR mutant. Tn7-borne expression of iscR in the iscR mutant restored survival percentage to that of wild-type P. aeruginosa. |
complete | |||||
|
enables |
GO:0000976 |
transcription regulatory region sequence-specific DNA binding |
ECO:0001807 |
electrophoretic mobility shift assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11212 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13397 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13397 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003690 |
double-stranded DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051536 |
iron-sulfur cluster binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Somprasong, N et al. (2012) Pseudomonas aeruginosa thiol peroxidase protects against hydrogen peroxide toxicity and displays atypical patterns of gene regulation. J. Bacteriol. 194 3904-12 PubMed GONUTS page
- ↑ 2.0 2.1 Romsang, A et al. (2014) The iron-sulphur cluster biosynthesis regulator IscR contributes to iron homeostasis and resistance to oxidants in Pseudomonas aeruginosa. PLoS ONE 9 e86763 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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