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PSEAE:Q9I0Z0

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Species (Taxon ID) Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228). (208964)
Gene Name(s) mexT (ECO:0000313 with EMBL:AAG05880.1)
Protein Name(s) Transcriptional regulator MexT (ECO:0000313 with EMBL:AAG05880.1)
External Links
UniProt Q9I0Z0
EMBL AE004091
PIR D83335
RefSeq NP_251182.1
WP_010895622.1
ProteinModelPortal Q9I0Z0
SMR Q9I0Z0
STRING 208964.PA2492
EnsemblBacteria AAG05880
GeneID 880417
KEGG pae:PA2492
PATRIC 19839449
PseudoCAP PA2492
HOGENOM HOG000103695
KO K18297
OMA SMEPTAR
OrthoDB EOG6ZH2FC
PhylomeDB Q9I0Z0
Proteomes UP000002438
GO GO:0003700
GO:0050709
GO:0045861
GO:1900377
Gene3D 1.10.10.10
InterPro IPR005119
IPR000847
IPR011991
Pfam PF00126
PF03466

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0044212

transcription regulatory region DNA binding

PMID:10515918[1]

ECO:0000315

F

FIG. 3. Effect of mexT on expression of mexE::lacZ

complete

GO:0010628

positive regulation of gene expression

PMID:10515918[1]

ECO:0000270

P

Fig. 3. pMEXT addition shows mexT positively regulates mexE:LacZ and qrh::lacZ

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:19846594[2]

ECO:0001808

reverse transcription polymerase chain reaction evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0032993

protein-DNA complex

PMID:20727012[3]

ECO:0005667

site-directed mutagenesis evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0032993

protein-DNA complex

PMID:19846594[2]

ECO:0005667

site-directed mutagenesis evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0032993

protein-DNA complex

PMID:20727012[3]

ECO:0001807

electrophoretic mobility shift assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0032993

protein-DNA complex

PMID:19846594[2]

ECO:0001807

electrophoretic mobility shift assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0001216

DNA-binding transcription activator activity

PMID:20727012[3]

ECO:0005667

site-directed mutagenesis evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0001216

DNA-binding transcription activator activity

PMID:19846594[2]

ECO:0005667

site-directed mutagenesis evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0001216

DNA-binding transcription activator activity

PMID:20727012[3]

ECO:0001807

electrophoretic mobility shift assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0001216

DNA-binding transcription activator activity

PMID:19846594[2]

ECO:0001807

electrophoretic mobility shift assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:20727012[3]

ECO:0005667

site-directed mutagenesis evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:19846594[2]

ECO:0005667

site-directed mutagenesis evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:20727012[3]

ECO:0001807

electrophoretic mobility shift assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:19846594[2]

ECO:0001807

electrophoretic mobility shift assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:1900377

negative regulation of secondary metabolite biosynthetic process

PMID:21075931[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050709

negative regulation of protein secretion

PMID:21075931[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:10515918[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045861

negative regulation of proteolysis

PMID:21075931[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

PMID:20727012[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000847

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000847

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Köhler, T et al. (1999) Characterization of MexT, the regulator of the MexE-MexF-OprN multidrug efflux system of Pseudomonas aeruginosa. J. Bacteriol. 181 6300-5 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Tian, ZX et al. (2009) Transcriptome profiling defines a novel regulon modulated by the LysR-type transcriptional regulator MexT in Pseudomonas aeruginosa. Nucleic Acids Res. 37 7546-59 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Maseda, H et al. (2010) Transcriptional regulation of the mexEF-oprN multidrug efflux pump operon by MexT and an unidentified repressor in nfxC-type mutant of Pseudomonas aeruginosa. FEMS Microbiol. Lett. 311 36-43 PubMed GONUTS page
  4. 4.0 4.1 4.2 Jin, Y et al. (2011) MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa. J. Bacteriol. 193 399-410 PubMed GONUTS page