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BORBU:O51712

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Species (Taxon ID) Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680). (224326)
Gene Name(s) rpoS (ECO:0000313 with EMBL:AAC67109.1)
Protein Name(s) RNA polymerase sigma factor (ECO:0000256 with RuleBase:RU000715)
External Links
UniProt O51712
EMBL AE000783
PIR B70196
RefSeq NP_212905.1
ProteinModelPortal O51712
STRING 224326.BB0771
EnsemblBacteria AAC67109
GeneID 1195628
KEGG bbu:BB_0771
PATRIC 20558203
KO K03087
OMA QINKYLM
OrthoDB EOG6D5G0W
BioCyc BBUR224326:G9SO-780-MONOMER
Proteomes UP000001807
GO GO:0003677
GO:0003700
GO:0016987
GO:0044008
GO:0006352
Gene3D 1.10.10.10
InterPro IPR014284
IPR000943
IPR009042
IPR007627
IPR007630
IPR013325
IPR013324
IPR011991
Pfam PF00140
PF04542
PF04545
PRINTS PR00046
SUPFAM SSF88659
SSF88946
TIGRFAMs TIGR02937
PROSITE PS00715
PS00716

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0044008

dissemination or transmission of symbiont from host by vector

PMID:22359504[1]

ECO:0000315

P

Figure 4. Images show the negative effects of a lack of RpoS has on spirochetes in the formation of mobile bodies and transmission of symbiont.

complete
CACAO 6511

involved_in

GO:0044008

dissemination or transmission of symbiont from host by vector

PMID:22359504[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0032993

protein-DNA complex

PMID:15489451[2]

ECO:0005667

site-directed mutagenesis evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0001216

DNA-binding transcription activator activity

PMID:15489451[2]

ECO:0005667

site-directed mutagenesis evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:15489451[2]

ECO:0005667

site-directed mutagenesis evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0001216

P

Seeded From UniProt

complete

involved_in

GO:2000142

regulation of DNA-templated transcription, initiation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016987

P

Seeded From UniProt

complete

involved_in

GO:2000142

regulation of DNA-templated transcription, initiation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016987

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009042

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000943
InterPro:IPR007627
InterPro:IPR007630
InterPro:IPR009042
InterPro:IPR013325
InterPro:IPR014284

F

Seeded From UniProt

complete

involved_in

GO:0006352

DNA-templated transcription, initiation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000943
InterPro:IPR007627
InterPro:IPR007630
InterPro:IPR009042
InterPro:IPR013325
InterPro:IPR014284

P

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000943
InterPro:IPR007627
InterPro:IPR007630
InterPro:IPR009042
InterPro:IPR013325
InterPro:IPR014284

P

Seeded From UniProt

complete

enables

GO:0016987

sigma factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009042

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0731

P

Seeded From UniProt

complete

enables

GO:0016987

sigma factor activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0731

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000173759

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Dunham-Ems, SM et al. (2012) Borrelia burgdorferi requires the alternative sigma factor RpoS for dissemination within the vector during tick-to-mammal transmission. PLoS Pathog. 8 e1002532 PubMed GONUTS page
  2. 2.0 2.1 2.2 Eggers, CH et al. (2004) Analysis of promoter elements involved in the transcriptional initiation of RpoS-dependent Borrelia burgdorferi genes. J. Bacteriol. 186 7390-402 PubMed GONUTS page