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CHICK:THB
Contents
Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
Gene Name(s) | THRB (synonyms: C-ERBA-BETA, NR1A2) | |
Protein Name(s) | Thyroid hormone receptor beta
Nuclear receptor subfamily 1 group A member 2 | |
External Links | ||
UniProt | P68306 | |
EMBL | X17504 M65207 Z50188 | |
PIR | S09625 | |
RefSeq | NP_990778.2 | |
UniGene | Gga.609 | |
ProteinModelPortal | P68306 | |
SMR | P68306 | |
IntAct | P68306 | |
STRING | 9031.ENSGALP00000018402 | |
PaxDb | P68306 | |
Ensembl | ENSGALT00000018423 ENSGALT00000031162 | |
GeneID | 396431 | |
KEGG | gga:396431 | |
CTD | 7068 | |
eggNOG | NOG272726 | |
GeneTree | ENSGT00760000118837 | |
HOGENOM | HOG000010313 | |
HOVERGEN | HBG005606 | |
InParanoid | P68306 | |
KO | K08362 | |
OrthoDB | EOG7TBC2V | |
PhylomeDB | P68306 | |
Reactome | REACT_258806 | |
NextBio | 20816472 | |
PRO | PR:P68306 | |
Proteomes | UP000000539 | |
ExpressionAtlas | P68306 | |
GO | GO:0070062 GO:0000790 GO:0031490 GO:0043565 GO:0003707 GO:0070324 GO:0004887 GO:0008270 GO:0008050 GO:0030522 GO:0007621 GO:0000122 GO:0009887 GO:0045944 GO:0008016 GO:0007605 GO:0060509 | |
Gene3D | 1.10.565.10 3.30.50.10 | |
InterPro | IPR008946 IPR000536 IPR001723 IPR001728 IPR001628 IPR013088 | |
Pfam | PF00104 PF00105 | |
PRINTS | PR00398 PR00047 PR00546 | |
SMART | SM00430 SM00399 | |
SUPFAM | SSF48508 | |
PROSITE | PS00031 PS51030 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000138) |
Seeded From UniProt |
complete | ||
enables |
GO:1990837 |
sequence-specific double-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0070324 |
thyroid hormone binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004879 |
nuclear receptor activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0090575 |
RNA polymerase II transcription factor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1352462 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060509 |
type I pneumocyte differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98742 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000546 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0038023 |
signaling receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104740 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0033993 |
response to lipid |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97747 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0030878 |
thyroid gland development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98742 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0030374 |
nuclear receptor transcription coactivator activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97747 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101884 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009887 |
animal organ morphogenesis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98742 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009755 |
hormone-mediated signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001941333 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009755 |
hormone-mediated signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000637753 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008134 |
transcription factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97856 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:103076 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000546 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0002154 |
thyroid hormone mediated signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001182181 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000546 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0000977 |
RNA polymerase II regulatory region sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000546 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0000976 |
transcription regulatory region sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000546 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101884 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043401 |
steroid hormone mediated signaling pathway |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003707 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003707 |
steroid hormone receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004879 |
nuclear receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001628 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Lassová, L et al. (2009) Thyroid hormone treatment of cultured chondrocytes mimics in vivo stimulation of collagen X mRNA by increasing BMP 4 expression. J. Cell. Physiol. 219 595-605 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
d
n
r
s
t
- Testudines + Archosauria group
- Theropoda
- GO:0030878 ! thyroid gland development
- GO:0070324 ! thyroid hormone binding
- GO:0002154 ! thyroid hormone receptor signaling pathway
- GO:0008134 ! transcription factor binding
- GO:0000976 ! transcription cis-regulatory region binding
- GO:0060509 ! type I pneumocyte differentiation