MOUSE:SOX11

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Sox11 (synonyms: Sox-11)
Protein Name(s)	Transcription factor SOX-11
External Links
UniProt	Q7M6Y2
EMBL	AF009414 AB108675 BK001484 AK165693 AK146514 BC062095 Z18960
CCDS	CCDS25849.1
RefSeq	NP_033260.4
UniGene	Mm.41702 Mm.466344
ProteinModelPortal	Q7M6Y2
SMR	Q7M6Y2
BioGrid	203398
STRING	10090.ENSMUSP00000078070
PhosphoSite	Q7M6Y2
MaxQB	Q7M6Y2
PRIDE	Q7M6Y2
Ensembl	ENSMUST00000079063
GeneID	20666
KEGG	mmu:20666
UCSC	uc007nfn.2
CTD	6664
MGI	MGI:98359
eggNOG	NOG130659
GeneTree	ENSGT00760000118988
HOGENOM	HOG000231874
HOVERGEN	HBG005040
InParanoid	Q7M6Y2
KO	K09268
OMA	NPDWCKT
OrthoDB	EOG7TMZVP
PhylomeDB	Q7M6Y2
TreeFam	TF351735
ChiTaRS	Sox11
NextBio	299129
PRO	PR:Q7M6Y2
Proteomes	UP000000589
Bgee	Q7M6Y2
CleanEx	MM_SOX11
Genevestigator	Q7M6Y2
GO	GO:0005737 GO:0005634 GO:0001158 GO:0001077 GO:0000979 GO:0003705 GO:0001105 GO:0003700 GO:0000976 GO:0008135 GO:0003211 GO:0061386 GO:0061303 GO:0048557 GO:0048704 GO:0061029 GO:0021782 GO:0014009 GO:0060022 GO:0001822 GO:0002089 GO:0060174 GO:0060425 GO:0060548 GO:0010629 GO:0060253 GO:0050672 GO:0000122 GO:2000678 GO:0014032 GO:0001841 GO:0060563 GO:0003357 GO:0014003 GO:0003151 GO:0030513 GO:0008284 GO:0010628 GO:0035332 GO:0046887 GO:2001111 GO:0050769 GO:0045666 GO:0045778 GO:0045669 GO:2000648 GO:0045944 GO:0045893 GO:0017015 GO:0072395 GO:0035914 GO:0001501 GO:0060023 GO:0061053 GO:0021510 GO:0048485 GO:0006366 GO:0060412
Gene3D	1.10.30.10
InterPro	IPR009071 IPR029551 IPR017386
PANTHER	PTHR10270:SF113
Pfam	PF00505
PIRSF	PIRSF038098
SMART	SM00398
SUPFAM	SSF47095
PROSITE	PS50118

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:2001111	positive regulation of lens epithelial cell proliferation	PMID:18423449^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:2000678	negative regulation of transcription regulatory region DNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P0C1G9	P		Seeded From UniProt	complete
involved_in	GO:2000648	positive regulation of stem cell proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
involved_in	GO:0061386	closure of optic fissure	PMID:18423449^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061303	cornea development in camera-type eye	PMID:18423449^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061053	somite development	PMID:20596238^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061029	eyelid development in camera-type eye	PMID:15254231^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060563	neuroepithelial cell differentiation	PMID:20646169^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060548	negative regulation of cell death	PMID:20596238^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060548	negative regulation of cell death	PMID:20646169^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060425	lung morphogenesis	PMID:15254231^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060412	ventricular septum morphogenesis	PMID:15254231^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060253	negative regulation of glial cell proliferation	PMID:19808959^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060174	limb bud formation	PMID:20596238^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060023	soft palate development	PMID:15254231^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060022	hard palate development	PMID:15254231^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050769	positive regulation of neurogenesis	PMID:19490090^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048704	embryonic skeletal system morphogenesis	PMID:15254231^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048557	embryonic digestive tract morphogenesis	PMID:15254231^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048485	sympathetic nervous system development	PMID:20147379^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0046887	positive regulation of hormone secretion	PMID:21527504^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:18505825^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:20147379^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:18423449^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:20596238^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:21527504^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045778	positive regulation of ossification	PMID:15254231^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045669	positive regulation of osteoblast differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	PMID:19808959^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	PMID:19490090^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035332	positive regulation of hippo signaling	PMID:20596238^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030513	positive regulation of BMP signaling pathway	PMID:18423449^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0021782	glial cell development	PMID:20646169^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0021782	glial cell development	PMID:20147379^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0021510	spinal cord development	PMID:20646169^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0014032	neural crest cell development	PMID:20596238^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0014009	glial cell proliferation	PMID:20147379^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	PMID:19808959^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	PMID:19808959^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	PMID:20596238^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P35716	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21527504^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:19490090^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:15456859^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0003357	noradrenergic neuron differentiation	PMID:20147379^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0003211	cardiac ventricle formation	PMID:20596238^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0003151	outflow tract morphogenesis	PMID:15254231^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0002089	lens morphogenesis in camera-type eye	PMID:18423449^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001841	neural tube formation	PMID:20596238^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001501	skeletal system development	PMID:20596238^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0001158	enhancer sequence-specific DNA binding	PMID:21527504^[8]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0001158	enhancer sequence-specific DNA binding	PMID:19808959^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	PMID:18505825^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PMID:18505825^[9]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_at:(SO:0001952)	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:21527504^[8]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0000976	transcription regulatory region sequence-specific DNA binding	PMID:18505825^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:19808959^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98359 PANTHER:PTN001616003 RGD:69351 UniProtKB:P35716	P		Seeded From UniProt	complete
part_of	GO:0044798	nuclear transcription factor complex	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103559 MGI:MGI:107543 MGI:MGI:98362 MGI:MGI:98363 MGI:MGI:98364 MGI:MGI:98366 MGI:MGI:98660 PANTHER:PTN000030384	C		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001616003 UniProtKB:P35716	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98363 PANTHER:PTN000030384	P		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103559 MGI:MGI:107543 MGI:MGI:2654070 MGI:MGI:98364 PANTHER:PTN000030384 UniProtKB:P48431 UniProtKB:Q06945	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000411 FB:FBgn0005612 FB:FBgn0005613 FB:FBgn0029123 FB:FBgn0036411 MGI:MGI:103559 MGI:MGI:107543 MGI:MGI:98357 MGI:MGI:98359 MGI:MGI:98363 MGI:MGI:98364 MGI:MGI:98366 MGI:MGI:98369 MGI:MGI:98660 PANTHER:PTN000030384 RGD:1565646 RGD:3759 RGD:69351 UniProtKB:P35713 UniProtKB:P35716 UniProtKB:P48430 UniProtKB:P48431 UniProtKB:Q05066 UniProtKB:Q06945 UniProtKB:Q9BT81 UniProtKB:Q9H6I2 WB:WBGene00004771	C		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103559 MGI:MGI:107543 MGI:MGI:98362 MGI:MGI:98363 MGI:MGI:98364 MGI:MGI:98366 MGI:MGI:98660 PANTHER:PTN000030384 ZFIN:ZDB-GENE-990715-6	F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98359 PANTHER:PTN001616003 UniProtKB:P35716	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000678	negative regulation of transcription regulatory region DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69351	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000648	positive regulation of stem cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060253	negative regulation of glial cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050672	negative regulation of lymphocyte proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:9632656^[12]	ECO:0000266	sequence orthology evidence used in manual assertion	RefSeq:NP_445801	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69351	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045778	positive regulation of ossification	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045669	positive regulation of osteoblast differentiation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045666	positive regulation of neuron differentiation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035914	skeletal muscle cell differentiation	PMID:20847309^[13]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010629	negative regulation of gene expression	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010628	positive regulation of gene expression	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69351	C		Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69351	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69351	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0003357	noradrenergic neuron differentiation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69351	P		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69351	F		Seeded From UniProt	complete
enables	GO:0001158	enhancer sequence-specific DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:9632656^[12]	ECO:0000266	sequence orthology evidence used in manual assertion	RefSeq:NP_445801	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	F		Seeded From UniProt	complete
enables	GO:0000976	transcription regulatory region sequence-specific DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69351	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P35716	P		Seeded From UniProt	complete
involved_in	GO:2000678	negative regulation of transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
involved_in	GO:0014003	oligodendrocyte development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	C		Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	F		Seeded From UniProt	complete
involved_in	GO:0003357	noradrenergic neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
involved_in	GO:0001822	kidney development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	P		Seeded From UniProt	complete
enables	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	F		Seeded From UniProt	complete
enables	GO:0000976	transcription regulatory region sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P0C1G9 ensembl:ENSRNOP00000040127	F		Seeded From UniProt	complete
involved_in	GO:2000648	positive regulation of stem cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0072395	signal transduction involved in cell cycle checkpoint	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0060253	negative regulation of glial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0050672	negative regulation of lymphocyte proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0045778	positive regulation of ossification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0045669	positive regulation of osteoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	C		Seeded From UniProt	complete
enables	GO:0001158	enhancer sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35716 ensembl:ENSP00000322568	P		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR029551	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0524	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
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References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Wurm, A et al. (2008) Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11. Exp. Eye Res. 86 895-907 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 ^2.9 Bhattaram, P et al. (2010) Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun 1 9 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 Sock, E et al. (2004) Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling. Mol. Cell. Biol. 24 6635-44 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 Thein, DC et al. (2010) The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development. J. Neurochem. 115 131-41 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Hide, T et al. (2009) Sox11 prevents tumorigenesis of glioma-initiating cells by inducing neuronal differentiation. Cancer Res. 69 7953-9 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Haslinger, A et al. (2009) Expression of Sox11 in adult neurogenic niches suggests a stage-specific role in adult neurogenesis. Eur. J. Neurosci. 29 2103-14 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 Potzner, MR et al. (2010) Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system. Development 137 775-84 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 Kim, HD et al. (2011) Class-C SOX transcription factors control GnRH gene expression via the intronic transcriptional enhancer. Mol. Endocrinol. 25 1184-96 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 Hoser, M et al. (2008) Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors. Mol. Cell. Biol. 28 4675-87 PubMed GONUTS page
↑ Tanaka, S et al. (2004) Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells. Mol. Cell. Biol. 24 8834-46 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 ^11.6 ^11.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^12.0 ^12.1 Kuhlbrodt, K et al. (1998) Cooperative function of POU proteins and SOX proteins in glial cells. J. Biol. Chem. 273 16050-7 PubMed GONUTS page
↑ Guo, D et al. (2010) Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress. Circ. Res. 107 1275-89 PubMed GONUTS page

[PMID:18423449-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Wurm, A et al. (2008) Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11. Exp. Eye Res. 86 895-907 PubMed GONUTS page

[PMID:20596238-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 ^2.9 Bhattaram, P et al. (2010) Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun 1 9 PubMed GONUTS page

[PMID:15254231-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 Sock, E et al. (2004) Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling. Mol. Cell. Biol. 24 6635-44 PubMed GONUTS page

[PMID:20646169-4] 4.0 ^4.1 ^4.2 ^4.3 Thein, DC et al. (2010) The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development. J. Neurochem. 115 131-41 PubMed GONUTS page

[PMID:19808959-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Hide, T et al. (2009) Sox11 prevents tumorigenesis of glioma-initiating cells by inducing neuronal differentiation. Cancer Res. 69 7953-9 PubMed GONUTS page

[PMID:19490090-6] 6.0 ^6.1 ^6.2 Haslinger, A et al. (2009) Expression of Sox11 in adult neurogenic niches suggests a stage-specific role in adult neurogenesis. Eur. J. Neurosci. 29 2103-14 PubMed GONUTS page

[PMID:20147379-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 Potzner, MR et al. (2010) Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system. Development 137 775-84 PubMed GONUTS page

[PMID:21527504-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 Kim, HD et al. (2011) Class-C SOX transcription factors control GnRH gene expression via the intronic transcriptional enhancer. Mol. Endocrinol. 25 1184-96 PubMed GONUTS page

[PMID:18505825-9] 9.0 ^9.1 ^9.2 ^9.3 Hoser, M et al. (2008) Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors. Mol. Cell. Biol. 28 4675-87 PubMed GONUTS page

[PMID:15456859-10] Tanaka, S et al. (2004) Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells. Mol. Cell. Biol. 24 8834-46 PubMed GONUTS page

[PMID:21873635-11] 11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 ^11.6 ^11.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:9632656-12] 12.0 ^12.1 Kuhlbrodt, K et al. (1998) Cooperative function of POU proteins and SOX proteins in glial cells. J. Biol. Chem. 273 16050-7 PubMed GONUTS page

[PMID:20847309-13] Guo, D et al. (2010) Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress. Circ. Res. 107 1275-89 PubMed GONUTS page

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