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MOUSE:PPARG

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Pparg (synonyms: Nr1c3)
Protein Name(s) Peroxisome proliferator-activated receptor gamma

PPAR-gamma Nuclear receptor subfamily 1 group C member 3

External Links
UniProt P37238
EMBL U09138
U01664
U01841
U10374
CCDS CCDS20439.1
CCDS51876.1
PIR A54101
RefSeq NP_001120802.1
NP_035276.2
XP_006505803.1
XP_006505804.1
XP_006505805.1
XP_006505806.1
XP_006505807.1
UniGene Mm.3020
ProteinModelPortal P37238
SMR P37238
BioGrid 202320
DIP DIP-60435N
IntAct P37238
STRING 10090.ENSMUSP00000000450
BindingDB P37238
ChEMBL CHEMBL2459
PhosphoSite P37238
PRIDE P37238
GeneID 19016
KEGG mmu:19016
UCSC uc012eqj.1
CTD 5468
MGI MGI:97747
eggNOG NOG266867
HOGENOM HOG000261626
HOVERGEN HBG106004
InParanoid P37238
KO K08530
PhylomeDB P37238
Reactome REACT_252217
REACT_27166
NextBio 295444
PRO PR:P37238
Proteomes UP000000589
Bgee P37238
CleanEx MM_PPARG
Genevestigator P37238
GO GO:0005737
GO:0005829
GO:0005654
GO:0005634
GO:0050544
GO:0003682
GO:0003677
GO:0004879
GO:0030374
GO:0001012
GO:0001228
GO:0043565
GO:0003700
GO:0003707
GO:0044212
GO:0050699
GO:0008270
GO:0050873
GO:0045165
GO:0071285
GO:0071407
GO:0030855
GO:0045444
GO:0006954
GO:0030522
GO:0015909
GO:0008285
GO:1900077
GO:0001818
GO:0090278
GO:0000122
GO:0045892
GO:0001890
GO:0045600
GO:0045944
GO:0045893
GO:0045598
GO:0060850
GO:0033993
GO:0032526
GO:0050872
Gene3D 1.10.565.10
3.30.50.10
InterPro IPR003074
IPR003077
IPR008946
IPR000536
IPR022590
IPR001723
IPR001628
IPR013088
Pfam PF00104
PF12577
PF00105
PRINTS PR01288
PR01291
PR00398
PR00047
SMART SM00430
SM00399
SUPFAM SSF48508
PROSITE PS00031
PS51030

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0010742

macrophage derived foam cell differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

involved_in

GO:0032094

response to food

PMID:19041764[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009416

response to light stimulus

PMID:19041764[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0070888

E-box binding

PMID:19041764[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:19041764[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042752

regulation of circadian rhythm

PMID:19041764[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0150079

negative regulation of neuroinflammatory response

PMID:30412727[2]

ECO:0000316

genetic interaction evidence used in manual assertion

RNAcentral:URS000024A59E_10090

P

Seeded From UniProt

complete

involved_in

GO:1903979

negative regulation of microglial cell activation

PMID:30412727[2]

ECO:0000316

genetic interaction evidence used in manual assertion

RNAcentral:URS000024A59E_10090

P

Seeded From UniProt

complete

involved_in

GO:1900077

negative regulation of cellular response to insulin stimulus

PMID:11387233[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0090278

negative regulation of peptide hormone secretion

PMID:11387233[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

has_input:(UniProtKB:P41159)

Seeded From UniProt

complete

enables

GO:0050544

arachidonic acid binding

PMID:9568715[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:16127449[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

PMID:16127449[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

PMID:16127449[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0033993

response to lipid

PMID:9568715[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001818

negative regulation of cytokine production

PMID:18566389[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:16127449[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050872

white fat cell differentiation

PMID:16132694[7]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045600

positive regulation of fat cell differentiation

PMID:16132694[7]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0060850

regulation of transcription involved in cell fate commitment

PMID:19324970[8]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:16239304[9]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:21035761[10]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045600

positive regulation of fat cell differentiation

PMID:19324970[8]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045600

positive regulation of fat cell differentiation

PMID:21035761[10]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

PMID:21035761[10]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0032526

response to retinoic acid

PMID:16239304[9]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0030374

nuclear receptor transcription coactivator activity

PMID:21035761[10]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0030374

nuclear receptor transcription coactivator activity

PMID:16239304[9]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:20498072[11]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:20498072[11]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:21035761[10]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

PMID:21035761[10]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:16239304[9]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0090575

RNA polymerase II transcription factor complex

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1352462
PANTHER:PTN000637751
UniProtKB:P11473
UniProtKB:P37231
UniProtKB:Q13133

C

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000546
MGI:MGI:104740
MGI:MGI:1352462
MGI:MGI:1352463
MGI:MGI:1352464
MGI:MGI:97747
MGI:MGI:97856
MGI:MGI:97857
MGI:MGI:97858
MGI:MGI:98742
MGI:MGI:98743
PANTHER:PTN000637751
RGD:3371
RGD:3857
RGD:61906
RGD:628831
UniProtKB:O62807
UniProtKB:O75469
UniProtKB:P10276
UniProtKB:P11473
UniProtKB:P37231
UniProtKB:P55055
UniProtKB:Q07869
UniProtKB:Q13133
UniProtKB:Q14994
UniProtKB:Q8JHU1
UniProtKB:Q96RI1
WB:WBGene00000908

P

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97747
PANTHER:PTN000637985

P

Seeded From UniProt

complete

enables

GO:0038023

signaling receptor activity

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104740
PANTHER:PTN000637751

F

Seeded From UniProt

complete

involved_in

GO:0033993

response to lipid

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97747
PANTHER:PTN001941333
RGD:3371

P

Seeded From UniProt

complete

involved_in

GO:0033993

response to lipid

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97747
PANTHER:PTN001182169
RGD:3371

P

Seeded From UniProt

complete

involved_in

GO:0032869

cellular response to insulin stimulus

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97747
PANTHER:PTN000638208
UniProtKB:P37231

P

Seeded From UniProt

complete

involved_in

GO:0032526

response to retinoic acid

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97747
PANTHER:PTN000638208
UniProtKB:O62807
UniProtKB:P37231

P

Seeded From UniProt

complete

enables

GO:0030374

nuclear receptor transcription coactivator activity

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97747
PANTHER:PTN000637751
UniProtKB:O62807
UniProtKB:P37231

F

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101884
PANTHER:PTN000637751

P

Seeded From UniProt

complete

involved_in

GO:0019216

regulation of lipid metabolic process

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000637985
RGD:3371

P

Seeded From UniProt

complete

involved_in

GO:0010887

negative regulation of cholesterol storage

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001182169
UniProtKB:P37231
UniProtKB:Q07869

P

Seeded From UniProt

complete

involved_in

GO:0009755

hormone-mediated signaling pathway

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001941333
UniProtKB:P10827

P

Seeded From UniProt

complete

enables

GO:0008289

lipid binding

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104740
PANTHER:PTN001182169
UniProtKB:Q03181
UniProtKB:Q07869

F

Seeded From UniProt

complete

enables

GO:0008144

drug binding

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001182169
UniProtKB:P37231
UniProtKB:Q03181
UniProtKB:Q07869

F

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97856
PANTHER:PTN000637751
RGD:3371
RGD:3534
UniProtKB:P10276
UniProtKB:P10827
UniProtKB:P37231
UniProtKB:Q03181
UniProtKB:Q07869
ZFIN:ZDB-GENE-000210-31

F

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:103076
PANTHER:PTN000637751

P

Seeded From UniProt

complete

involved_in

GO:0006631

fatty acid metabolic process

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104740
PANTHER:PTN001182169
RGD:3369

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000546
FB:FBgn0000568
MGI:MGI:101884
MGI:MGI:1346307
MGI:MGI:1352462
MGI:MGI:1352463
MGI:MGI:2444210
MGI:MGI:97747
MGI:MGI:97856
MGI:MGI:97858
MGI:MGI:98742
MGI:MGI:98743
PANTHER:PTN000637751
RGD:3369
RGD:3370
RGD:3371
RGD:3534
RGD:3857
RGD:61909
RGD:621400
RGD:628831
UniProtKB:O62807
UniProtKB:P04625
UniProtKB:P10276
UniProtKB:P10826
UniProtKB:P10827
UniProtKB:P11473
UniProtKB:P13631
UniProtKB:P37231
UniProtKB:P55055
UniProtKB:P68306
UniProtKB:Q07869
UniProtKB:Q13133
UniProtKB:Q14995
WB:WBGene00000908
WB:WBGene00003607
WB:WBGene00004786
ZFIN:ZDB-GENE-990415-263

C

Seeded From UniProt

complete

enables

GO:0005504

fatty acid binding

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001182169
RGD:3370

F

Seeded From UniProt

complete

enables

GO:0001227

DNA-binding transcription repressor activity, RNA polymerase II-specific

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101884
PANTHER:PTN001182169

F

Seeded From UniProt

complete

enables

GO:0001103

RNA polymerase II repressing transcription factor binding

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001182169
UniProtKB:Q07869

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000546
PANTHER:PTN000637751
RGD:61906

F

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000546
FB:FBgn0015240
MGI:MGI:97856
MGI:MGI:97857
MGI:MGI:97858
PANTHER:PTN000637751
UniProtKB:O75469
UniProtKB:P20393
UniProtKB:Q14994
UniProtKB:Q96RI1
WB:WBGene00004786

F

Seeded From UniProt

complete

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000546
MGI:MGI:98742
PANTHER:PTN000637751
RGD:628827
UniProtKB:Q96RI1

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:21873635[12]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101884
MGI:MGI:2449205
MGI:MGI:97747
MGI:MGI:97856
MGI:MGI:97857
MGI:MGI:97858
MGI:MGI:98743
PANTHER:PTN001941333
UniProtKB:P20393
UniProtKB:P37231
UniProtKB:Q07869
WB:WBGene00004786

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0002674

negative regulation of acute inflammatory response

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0002024

diet induced thermogenesis

PMID:24703703[13]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2651605

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0002021

response to dietary excess

PMID:24703703[13]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001890

placenta development

PMID:17463056[14]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

results_in_development_of:(EMAPA:16042)|results_in_development_of:(EMAPA:35689)

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:23275342[15]

ECO:0000314

direct assay evidence used in manual assertion

F

  • occurs_in:(CL:0000136)
  • has_regulation_target:(MGI:MGI:1916202)

Seeded From UniProt

complete

enables

GO:0001012

RNA polymerase II regulatory region DNA binding

PMID:15175325[16]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:8041794[17]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0000122

negative regulation of transcription by RNA polymerase II

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:2000230

negative regulation of pancreatic stellate cell proliferation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1905563

negative regulation of vascular endothelial cell proliferation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1905461

positive regulation of vascular associated smooth muscle cell apoptotic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1904706

negative regulation of vascular smooth muscle cell proliferation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

part_of

GO:0090575

RNA polymerase II transcription factor complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0071407

cellular response to organic cyclic compound

PMID:12055200[18]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0071404

cellular response to low-density lipoprotein particle stimulus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0071285

cellular response to lithium ion

PMID:15673614[19]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0061614

pri-miRNA transcription by RNA polymerase II

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060965

negative regulation of gene silencing by miRNA

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060336

negative regulation of interferon-gamma-mediated signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060100

positive regulation of phagocytosis, engulfment

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051974

negative regulation of telomerase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

enables

GO:0051393

alpha-actinin binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051091

positive regulation of DNA-binding transcription factor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050873

brown fat cell differentiation

PMID:18492766[20]

ECO:0000314

direct assay evidence used in manual assertion

P

regulates_o_results_in_acquisition_of_features_of:(CL:0000136)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050872

white fat cell differentiation

PMID:18492766[20]

ECO:0000314

direct assay evidence used in manual assertion

P

results_in_acquisition_of_features_of:(CL:0000136)

Seeded From UniProt

complete

enables

GO:0050699

WW domain binding

PMID:22292086[21]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0050699

WW domain binding

PMID:22292086[21]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37238

F

Seeded From UniProt

complete

enables

GO:0050693

LBD domain binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

enables

GO:0050692

DBD domain binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048714

positive regulation of oligodendrocyte differentiation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048662

negative regulation of smooth muscle cell proliferation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048469

cell maturation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

enables

GO:0046965

retinoid X receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0046321

positive regulation of fatty acid oxidation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:23499423[22]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:894332
MGI:MGI:98214

P

  • has_regulation_target:(MGI:MGI:1917923)
  • occurs_in:(CL:0000449)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:26427354[23]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

  • occurs_in:(CL:0000136)
  • has_regulation_target:(MGI:MGI:2675492)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:16099986[24]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:12037571[25]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045893

positive regulation of transcription, DNA-templated

PMID:15684432[26]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045893

positive regulation of transcription, DNA-templated

PMID:14744933[27]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045892

negative regulation of transcription, DNA-templated

PMID:15681609[28]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045713

low-density lipoprotein particle receptor biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045598

regulation of fat cell differentiation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:17595322[29]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q6RI63

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:19066220[30]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:1337080

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:17905753[31]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:1096393

P

regulates_o_results_in_acquisition_of_features_of:(CL:0000448)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:16099986[24]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:1917649

P

results_in_acquisition_of_features_of:(CL:0000136)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:22292086[21]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:19066220[30]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

regulates_o_results_in_acquisition_of_features_of:(CL:0000136)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:15728361[32]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:15175325[16]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:12502791[33]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:12097321[34]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:12037571[25]

ECO:0000314

direct assay evidence used in manual assertion

P

results_in_acquisition_of_features_of:(CL:0000057)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:10937998[35]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045165

cell fate commitment

PMID:15687259[36]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:102784

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045165

cell fate commitment

PMID:24703703[13]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2651605

P

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

F

Seeded From UniProt

complete

enables

GO:0043621

protein self-association

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

contributes_to

GO:0043565

sequence-specific DNA binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043537

negative regulation of blood vessel endothelial cell migration

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043388

positive regulation of DNA binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043065

positive regulation of apoptotic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042953

lipoprotein transport

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042593

glucose homeostasis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

enables

GO:0042277

peptide binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035357

peroxisome proliferator activated receptor signaling pathway

PMID:17595322[29]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q6RI63

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035357

peroxisome proliferator activated receptor signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

enables

GO:0033613

activating transcription factor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032966

negative regulation of collagen biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032869

cellular response to insulin stimulus

PMID:26629404[37]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032869

cellular response to insulin stimulus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032526

response to retinoic acid

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030855

epithelial cell differentiation

PMID:15687259[36]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:102784

P

results_in_acquisition_of_features_of:(CL:0000066)

Seeded From UniProt

complete

enables

GO:0030374

nuclear receptor transcription coactivator activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

enables

GO:0030331

estrogen receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030308

negative regulation of cell growth

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030224

monocyte differentiation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

enables

GO:0019903

protein phosphatase binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

F

Seeded From UniProt

complete

enables

GO:0019899

enzyme binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0019395

fatty acid oxidation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0019216

regulation of lipid metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0016525

negative regulation of angiogenesis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0015909

long-chain fatty acid transport

PMID:17463056[14]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(EMAPA:16042)|occurs_in:(EMAPA:35689)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010891

negative regulation of sequestering of triglyceride

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010887

negative regulation of cholesterol storage

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010871

negative regulation of receptor biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010745

negative regulation of macrophage derived foam cell differentiation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010742

macrophage derived foam cell differentiation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010468

regulation of gene expression

PMID:24703703[13]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2651605

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0008285

negative regulation of cell population proliferation

PMID:12370429[38]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2384321

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0008285

negative regulation of cell population proliferation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0008217

regulation of blood pressure

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

enables

GO:0008144

drug binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

F

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007165

signal transduction

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006919

activation of cysteine-type endopeptidase activity involved in apoptotic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006357

regulation of transcription by RNA polymerase II

PMID:26629404[37]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

has_regulation_target:(MGI:MGI:3029307)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006357

regulation of transcription by RNA polymerase II

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:15164767[39]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:12163159[40]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21669876[41]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:15164767[39]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:12163159[40]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

C

Seeded From UniProt

complete

enables

GO:0004879

nuclear receptor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:12037571[25]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:3371

F

Seeded From UniProt

complete

enables

GO:0003690

double-stranded DNA binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

PMID:23775123[42]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

PMID:23499423[22]

ECO:0000314

direct assay evidence used in manual assertion

F

  • occurs_in:(CL:0000449)
  • has_direct_input:(MGI:MGI:1917923)

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

PMID:23275342[15]

ECO:0000314

direct assay evidence used in manual assertion

F

has_participant:(MGI:MGI:88038)|has_participant:(MGI:MGI:1916202)

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

PMID:19066220[30]

ECO:0000314

direct assay evidence used in manual assertion

F

has_participant:(MGI:MGI:88038)

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:15681609[28]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P28700

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:8041794[17]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:15681609[28]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:15232616[43]

ECO:0000314

direct assay evidence used in manual assertion

F

  • occurs_in:(CL:0000136)
  • has_participant:(MGI:MGI:95679)

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:12037571[25]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P37231

F

Seeded From UniProt

complete

involved_in

GO:0043401

steroid hormone mediated signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003707

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001723
InterPro:IPR003074
InterPro:IPR003077

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628

F

Seeded From UniProt

complete

enables

GO:0003707

steroid hormone receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001723

F

Seeded From UniProt

complete

enables

GO:0004879

nuclear receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003074
InterPro:IPR003077

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR003074
InterPro:IPR003077

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR003074
InterPro:IPR003077
InterPro:IPR013088

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR013088

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:22226965[44]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:23840343[45]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0002334)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045444

fat cell differentiation

PMID:22226965[44]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-MMU-9017440
Reactome:R-MMU-556760
Reactome:R-MMU-4717507
Reactome:R-MMU-442515
Reactome:R-MMU-442475

ECO:0000304

author statement supported by traceable reference used in manual assertion





C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006954

inflammatory response

PMID:12163159[40]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004879

nuclear receptor activity

PMID:12163159[40]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0048511

rhythmic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0090

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

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