Category:GO:0001227 ! DNA-binding transcription repressor activity, RNA polymerase II-specific

name: DNA-binding transcription repressor activity, RNA polymerase II-specific
namespace: molecular_function
alt_id: GO:0001078
alt_id: GO:0001206
alt_id: GO:0001210
alt_id: GO:0001214
def: "A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II." [GOC:txnOH-2018]
comment: For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.
synonym: "distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific" NARROW []
synonym: "metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription" NARROW []
synonym: "metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" NARROW []
synonym: "proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific" NARROW []
synonym: "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" NARROW []
synonym: "RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription" NARROW []
synonym: "RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription" EXACT []
synonym: "RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding" NARROW []
synonym: "RNA polymerase II transcriptional repressor activity, metal ion regulated proximal promoter sequence-specific DNA binding" NARROW []
synonym: "sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription" NARROW []
synonym: "transcriptional repressor activity, metal ion regulated sequence-specific DNA binding" NARROW []
synonym: "transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding" NARROW []
synonym: "transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding" NARROW []
synonym: "transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding" EXACT []
is_a: GO:0000981 ! DNA-binding transcription factor activity, RNA polymerase II-specific
is_a: GO:0001217 ! DNA-binding transcription repressor activity
relationship: part_of: GO:0000122 ! negative regulation of transcription by RNA polymerase II
intersection_of: GO:0140110 ! transcription regulator activity
intersection_of: has_part GO:0000977 ! RNA polymerase II transcription regulatory region sequence-specific DNA binding
intersection_of: part_of GO:0000122 ! negative regulation of transcription by RNA polymerase II

AmiGO <GOterm>GO:0001227</GOterm>
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