GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

HUMAN:THA11

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) THAP11
Protein Name(s) THAP domain-containing protein 11
External Links
UniProt Q96EK4
EMBL AK289367
BC012182
EF036502
AB015338
CCDS CCDS10847.1
RefSeq NP_065190.2
UniGene Hs.632200
PDB 2LAU
PDBsum 2LAU
ProteinModelPortal Q96EK4
SMR Q96EK4
BioGrid 121453
IntAct Q96EK4
MINT MINT-8362103
STRING 9606.ENSP00000304689
PhosphoSite Q96EK4
DMDM 209572685
MaxQB Q96EK4
PaxDb Q96EK4
PRIDE Q96EK4
DNASU 57215
Ensembl ENST00000303596
GeneID 57215
KEGG hsa:57215
UCSC uc002euo.3
CTD 57215
GeneCards GC16P067876
HGNC HGNC:23194
HPA HPA041434
HPA042189
MIM 609119
neXtProt NX_Q96EK4
PharmGKB PA134979842
eggNOG NOG45430
GeneTree ENSGT00390000006585
HOGENOM HOG000154562
HOVERGEN HBG062269
InParanoid Q96EK4
OMA TGHRVCS
OrthoDB EOG7WQ7TG
PhylomeDB Q96EK4
TreeFam TF331359
GenomeRNAi 57215
NextBio 63333
PRO PR:Q96EK4
Proteomes UP000005640
Bgee Q96EK4
CleanEx HS_THAP11
ExpressionAtlas Q96EK4
Genevestigator Q96EK4
GO GO:0005737
GO:0045171
GO:0005634
GO:0003677
GO:0008270
GO:0006355
GO:0006351
InterPro IPR006612
Pfam PF05485
SMART SM00692
SM00980
PROSITE PS50950

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

GO_REF:0000113

ECO:0005556

multiple sequence alignment evidence used in manual assertion

UniProtKB:D3ZHX2
UniProtKB:E1BL80
UniProtKB:E2RFZ3
UniProtKB:F6PKC2
UniProtKB:F6UCV2
UniProtKB:F6YKX2
UniProtKB:F7DLK8
UniProtKB:H2R539
UniProtKB:H2RHM6
UniProtKB:Q9CUX1
UniProtKB:Q9JJD0

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:19274049[1]

ECO:0000255

match to sequence model evidence used in manual assertion

InterPro:IPR006612

F

Seeded From UniProt

complete

enables

GO:0001227

DNA-binding transcription repressor activity, RNA polymerase II-specific

PMID:19008924[2]

ECO:0000314

direct assay evidence used in manual assertion

F

  • has_regulation_target:(NCBI_Gene:4609)
  • occurs_at:(SO:0001952)

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:19008924[2]

ECO:0000314

direct assay evidence used in manual assertion

P

has_regulation_target:(NCBI_Gene:4609)

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:19008924[2]

ECO:0000314

direct assay evidence used in manual assertion

F

has_regulation_target:(NCBI_Gene:4609)

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

PMID:23306615[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:23306615[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002736083
UniProtKB:Q96EK4

F

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002736083
UniProtKB:Q96EK4

C

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002736083
UniProtKB:Q96EK4

F

Seeded From UniProt

complete

part_of

GO:0045171

intercellular bridge

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006612

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
  2. 2.0 2.1 2.2 Zhu, CY et al. (2009) Cell growth suppression by thanatos-associated protein 11(THAP11) is mediated by transcriptional downregulation of c-Myc. Cell Death Differ. 16 395-405 PubMed GONUTS page
  3. 3.0 3.1 Gervais, V et al. (2013) NMR studies of a new family of DNA binding proteins: the THAP proteins. J. Biomol. NMR 56 3-15 PubMed GONUTS page
  4. 4.0 4.1 4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page