HUMAN:TYY1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	YY1 (synonyms: INO80S)
Protein Name(s)	Transcriptional repressor protein YY1 Delta transcription factor INO80 complex subunit S NF-E1 Yin and yang 1 YY-1
External Links
UniProt	P25490
EMBL	M77698 M76541 Z14077 BC037308 BC065366
CCDS	CCDS9957.1
PIR	A40350
RefSeq	NP_003394.1
UniGene	Hs.388927 Hs.603118
PDB	1UBD 1ZNM 4C5I
PDBsum	1UBD 1ZNM 4C5I
ProteinModelPortal	P25490
SMR	P25490
BioGrid	113360
DIP	DIP-150N
IntAct	P25490
MINT	MINT-157439
STRING	9606.ENSP00000262238
PhosphoSite	P25490
DMDM	3915889
MaxQB	P25490
PaxDb	P25490
PeptideAtlas	P25490
PRIDE	P25490
DNASU	7528
Ensembl	ENST00000262238
GeneID	7528
KEGG	hsa:7528
UCSC	uc001ygy.2
CTD	7528
GeneCards	GC14P101221
HGNC	HGNC:12856
HPA	CAB009392 HPA001119
MIM	600013
neXtProt	NX_P25490
PharmGKB	PA37445
eggNOG	COG5048
GeneTree	ENSGT00770000120559
HOGENOM	HOG000008232
HOVERGEN	HBG006823
InParanoid	P25490
KO	K09201
OMA	GGRKWEQ
PhylomeDB	P25490
TreeFam	TF106493
SignaLink	P25490
ChiTaRS	YY1
EvolutionaryTrace	P25490
GeneWiki	YY1
GenomeRNAi	7528
NextBio	29449
PMAP-CutDB	P25490
PRO	PR:P25490
Proteomes	UP000005640
Bgee	P25490
CleanEx	HS_YY1
ExpressionAtlas	P25490
Genevestigator	P25490
GO	GO:0031011 GO:0016363 GO:0005634 GO:0031519 GO:0005667 GO:0003677 GO:0000400 GO:0003723 GO:0001078 GO:0003700 GO:0003713 GO:0003714 GO:0044212 GO:0008270 GO:0009952 GO:0048593 GO:0030154 GO:0006974 GO:0034644 GO:0051276 GO:0000724 GO:0000122 GO:0006357 GO:0034696 GO:0010225 GO:0006403 GO:0007283
Gene3D	3.30.160.60
InterPro	IPR017114 IPR007087 IPR015880 IPR013087
Pfam	PF00096
PIRSF	PIRSF037113
SMART	SM00355
PROSITE	PS00028 PS50157

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0032688	negative regulation of interferon-beta production	PMID:22065573^[1]	ECO:0000315			P		Fig. 2DE, Fig. 5BC, and Fig. 6	complete CACAO 3240
	GO:0005634	nucleus	PMID:22065573^[1]	ECO:0000315			C		Fig. 5A and Fig. 6C	complete CACAO 3241
	GO:0010629	negative regulation of gene expression	PMID:22065573^[1]	ECO:0000315			P		Fig. 5CD	complete CACAO 3242
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GO_REF:0000113	ECO:0005556	multiple sequence alignment evidence used in manual assertion	UniProtKB:E9Q3T6 UniProtKB:O14978 UniProtKB:O95125 UniProtKB:O95863 UniProtKB:P10071 UniProtKB:P10754 UniProtKB:P17028 UniProtKB:P28698 UniProtKB:P36508 UniProtKB:P41183 UniProtKB:P47806 UniProtKB:P52738 UniProtKB:Q02085 UniProtKB:Q05516 UniProtKB:Q08376 UniProtKB:Q0VDQ9 UniProtKB:Q16600 UniProtKB:Q61967 UniProtKB:Q6DJT9 UniProtKB:Q6NUN9 UniProtKB:Q86UQ0 UniProtKB:Q8CIV7 UniProtKB:Q8K0L9 UniProtKB:Q8K3J5 UniProtKB:Q8NI51 UniProtKB:Q91ZD1 UniProtKB:Q96RE9 UniProtKB:Q99684 UniProtKB:Q9BU19 UniProtKB:Q9ESP5 UniProtKB:Q9GZX5 UniProtKB:Q9H116 UniProtKB:Q9NQX1 UniProtKB:Q9NZL3 UniProtKB:Q9QY31 UniProtKB:Q9UM63 UniProtKB:Q9UPG8 UniProtKB:Q9UQR1 UniProtKB:Q9WTJ2 UniProtKB:Q9Y2X9 UniProtKB:Q9Y473 UniProtKB:Q9Y5A6	F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:19274049^[2]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0032688	negative regulation of interferon-beta production	PMID:16260628^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16260628^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:16260628^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:10791971^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0000987	proximal promoter sequence-specific DNA binding	PMID:16260628^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	PMID:22065573^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:22065573^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q00899	F	occurs_at:(SO:0001952)	Seeded From UniProt	complete
enables	GO:0046332	SMAD binding	PMID:15329343^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0001158	enhancer sequence-specific DNA binding	PMID:15329343^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0034644	cellular response to UV	PMID:18026119^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0031011	Ino80 complex	PMID:21303910^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031011	Ino80 complex	PMID:18026119^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0010225	response to UV-C	PMID:18026119^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	PMID:18026119^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:18026119^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	PMID:18026119^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0000400	four-way junction DNA binding	PMID:18026119^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0002521 FB:FBgn0035997 MGI:MGI:99187 PANTHER:PTN000360827 RGD:3982 SGD:S000000270 UniProtKB:O15391 UniProtKB:Q2V3L3	F		Seeded From UniProt	complete
part_of	GO:0031519	PcG protein complex	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0002521 MGI:MGI:99150 PANTHER:PTN000360827	C		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99150 PANTHER:PTN000360827 RGD:3982	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0002521 FB:FBgn0035997 MGI:MGI:99150 MGI:MGI:99187 PANTHER:PTN000360827 RGD:3982 SGD:S000000270 SGD:S000002450 UniProtKB:O15391 UniProtKB:P25490 UniProtKB:Q2V3L3	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0002521 MGI:MGI:1277969 MGI:MGI:99150 PANTHER:PTN000360827 UniProtKB:P25490	F		Seeded From UniProt	complete
enables	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0002521 PANTHER:PTN000360827	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99150 MGI:MGI:99187 PANTHER:PTN000360827 SGD:S000002450	F		Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0002521 MGI:MGI:99150 PANTHER:PTN000360827	C		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	PMID:9857059^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	PMID:21729784^[10]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:21729784^[10]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:9857059^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
involved_in	GO:0051276	chromosome organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
involved_in	GO:0048593	camera-type eye morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
part_of	GO:0031519	PcG protein complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	C		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
involved_in	GO:0010225	response to UV-C	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
involved_in	GO:0009952	anterior/posterior pattern specification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
involved_in	GO:0007283	spermatogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
involved_in	GO:0006403	RNA localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	F		Seeded From UniProt	complete
enables	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	F		Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	C		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q00899 ensembl:ENSMUSP00000021692	P		Seeded From UniProt	complete
involved_in	GO:0071347	cellular response to interleukin-1	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	P		Seeded From UniProt	complete
involved_in	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	F		Seeded From UniProt	complete
involved_in	GO:0034696	response to prostaglandin F	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	P		Seeded From UniProt	complete
part_of	GO:0016363	nuclear matrix	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	C		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	C		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	C		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CHJ4 ensembl:ENSRNOP00000005743	P		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013087	F		Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	PMID:1655281^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0006357	regulation of transcription by RNA polymerase II	PMID:1655281^[11] Reactome:R-HSA-8866910	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0003714	transcription corepressor activity	PMID:1655281^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	PMID:1946405^[12]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:1946405^[12]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0016579	protein deubiquitination	Reactome:R-HSA-5688426	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-HSA-9009065 Reactome:R-HSA-8864453 Reactome:R-HSA-5689630 Reactome:R-HSA-5689544	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006310	DNA recombination	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0233	P		Seeded From UniProt	complete
involved_in	GO:0007283	spermatogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0744	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539	C		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
part_of	GO:0016363	nuclear matrix	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0181	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Siednienko, J et al. (2011) Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1. J. Biol. Chem. 286 44750-63 PubMed GONUTS page
↑ Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Klar, M & Bode, J (2005) Enhanceosome formation over the beta interferon promoter underlies a remote-control mechanism mediated by YY1 and YY2. Mol. Cell. Biol. 25 10159-70 PubMed GONUTS page
↑ Ko, YG et al. (2000) Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis. J. Cell Biol. 149 567-74 PubMed GONUTS page
↑ ^5.0 ^5.1 Lee, KH et al. (2004) SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer. Development 131 4709-23 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 Wu, S et al. (2007) A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair. Nat. Struct. Mol. Biol. 14 1165-72 PubMed GONUTS page
↑ Chen, L et al. (2011) Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. J. Biol. Chem. 286 11283-9 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 ^8.6 ^8.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^9.0 ^9.1 Du, K et al. (1998) Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals. J. Biol. Chem. 273 35208-15 PubMed GONUTS page
↑ ^10.0 ^10.1 Jeon, Y & Lee, JT (2011) YY1 tethers Xist RNA to the inactive X nucleation center. Cell 146 119-33 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 Shi, Y et al. (1991) Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein. Cell 67 377-88 PubMed GONUTS page
↑ ^12.0 ^12.1 Park, K & Atchison, ML (1991) Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site. Proc. Natl. Acad. Sci. U.S.A. 88 9804-8 PubMed GONUTS page

[PMID:22065573-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Siednienko, J et al. (2011) Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1. J. Biol. Chem. 286 44750-63 PubMed GONUTS page

[PMID:19274049-2] Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page

[PMID:16260628-3] 3.0 ^3.1 ^3.2 ^3.3 Klar, M & Bode, J (2005) Enhanceosome formation over the beta interferon promoter underlies a remote-control mechanism mediated by YY1 and YY2. Mol. Cell. Biol. 25 10159-70 PubMed GONUTS page

[PMID:10791971-4] Ko, YG et al. (2000) Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis. J. Cell Biol. 149 567-74 PubMed GONUTS page

[PMID:15329343-5] 5.0 ^5.1 Lee, KH et al. (2004) SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer. Development 131 4709-23 PubMed GONUTS page

[PMID:18026119-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 Wu, S et al. (2007) A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair. Nat. Struct. Mol. Biol. 14 1165-72 PubMed GONUTS page

[PMID:21303910-7] Chen, L et al. (2011) Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. J. Biol. Chem. 286 11283-9 PubMed GONUTS page

[PMID:21873635-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 ^8.6 ^8.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:9857059-9] 9.0 ^9.1 Du, K et al. (1998) Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals. J. Biol. Chem. 273 35208-15 PubMed GONUTS page

[PMID:21729784-10] 10.0 ^10.1 Jeon, Y & Lee, JT (2011) YY1 tethers Xist RNA to the inactive X nucleation center. Cell 146 119-33 PubMed GONUTS page

[PMID:1655281-11] 11.0 ^11.1 ^11.2 Shi, Y et al. (1991) Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein. Cell 67 377-88 PubMed GONUTS page

[PMID:1946405-12] 12.0 ^12.1 Park, K & Atchison, ML (1991) Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site. Proc. Natl. Acad. Sci. U.S.A. 88 9804-8 PubMed GONUTS page

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HUMAN:TYY1

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