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CHICK:HHEX

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) HHEX (synonyms: PRH)
Protein Name(s) Hematopoietically-expressed homeobox protein HHEX

Homeobox protein HEX Homeobox protein PRH

External Links
UniProt Q05502
EMBL X64711
PIR S78063
RefSeq NP_990583.1
UniGene Gga.3316
ProteinModelPortal Q05502
SMR Q05502
STRING 9031.ENSGALP00000038950
PaxDb Q05502
GeneID 396182
KEGG gga:396182
CTD 3087
eggNOG NOG252905
HOGENOM HOG000049110
HOVERGEN HBG055460
InParanoid Q05502
KO K08024
PhylomeDB Q05502
NextBio 20816236
PRO PR:Q05502
Proteomes UP000000539
GO GO:0005634
GO:0043565
GO:0030154
GO:0007275
GO:0045892
GO:0006351
Gene3D 1.10.10.60
InterPro IPR017970
IPR001356
IPR020479
IPR009057
Pfam PF00046
PRINTS PR00024
SMART SM00389
SUPFAM SSF46689
PROSITE PS00027
PS50071

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P43120

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:1360645[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:1360645[1]

ECO:0000305

curator inference used in manual assertion

GO:0043565

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P43120

C

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001963821
RGD:619932

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96086
PANTHER:PTN001963821
PomBase:SPBC21B10.13c
RGD:619932
UniProtKB:Q03014
WB:WBGene00004011

C

Seeded From UniProt

complete

enables

GO:0001227

DNA-binding transcription repressor activity, RNA polymerase II-specific

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96086
PANTHER:PTN001963821

F

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96086
PANTHER:PTN001963821

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96086
PANTHER:PTN001963821
PomBase:SPBC21B10.13c
UniProtKB:Q03014
ZFIN:ZDB-GENE-980526-299

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001356
InterPro:IPR009057
InterPro:IPR020479

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238
UniProtKB-KW:KW-0371

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Crompton, MR et al. (1992) Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells. Nucleic Acids Res. 20 5661-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page