CHICK:HAND1

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	HAND1 (synonyms: EHAND)
Protein Name(s)	Heart- and neural crest derivatives-expressed protein 1 Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1 eHAND
External Links
UniProt	Q90691
EMBL	U40041
RefSeq	NP_990296.1
UniGene	Gga.478
ProteinModelPortal	Q90691
GeneID	395812
KEGG	gga:395812
CTD	9421
HOVERGEN	HBG051880
InParanoid	Q90691
KO	K09071
PhylomeDB	Q90691
NextBio	20815880
PRO	PR:Q90691
Proteomes	UP000000539
GO	GO:0005634 GO:0003677 GO:0007275 GO:0006355 GO:0006351
Gene3D	4.10.280.10
InterPro	IPR011598
Pfam	PF00010
SMART	SM00353
SUPFAM	SSF47459
PROSITE	PS50888

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	P	Seeded From UniProt	complete
part_of	GO:0090575	RNA polymerase II transcription factor complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	C	Seeded From UniProt	complete
involved_in	GO:0060411	cardiac septum morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	P	Seeded From UniProt	complete
involved_in	GO:0055010	ventricular cardiac muscle tissue morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	P	Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	F	Seeded From UniProt	complete
involved_in	GO:0043433	negative regulation of DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	P	Seeded From UniProt	complete
enables	GO:0043425	bHLH transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	F	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	F	Seeded From UniProt	complete
involved_in	GO:0006366	transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	C	Seeded From UniProt	complete
involved_in	GO:0003219	cardiac right ventricle formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	P	Seeded From UniProt	complete
involved_in	GO:0003218	cardiac left ventricle formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	P	Seeded From UniProt	complete
enables	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	F	Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	F	Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	F	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O96004 ensembl:ENSP00000231121	P	Seeded From UniProt	complete
involved_in	GO:0061371	determination of heart left/right asymmetry	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
involved_in	GO:0060536	cartilage morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
involved_in	GO:0060485	mesenchyme development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
involved_in	GO:0055010	ventricular cardiac muscle tissue morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	F	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	F	Seeded From UniProt	complete
involved_in	GO:0043433	negative regulation of DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
enables	GO:0043425	bHLH transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	F	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	F	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	F	Seeded From UniProt	complete
involved_in	GO:0035050	embryonic heart tube development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	F	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	F	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
part_of	GO:0005730	nucleolus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	C	Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	F	Seeded From UniProt	complete
involved_in	GO:0003144	embryonic heart tube formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
involved_in	GO:0001947	heart looping	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
involved_in	GO:0001707	mesoderm formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q64279 ensembl:ENSMUSP00000046999	P	Seeded From UniProt	complete
enables	GO:0046983	protein dimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011598 InterPro:IPR036638	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P	Seeded From UniProt	complete
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CHICK:HAND1

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