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CHICK:IRF8

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) IRF8 (synonyms: ICSBP, ICSBP1)
Protein Name(s) Interferon regulatory factor 8

IRF-8 Interferon consensus sequence-binding protein ICSBP

External Links
UniProt Q90871
EMBL L39767
RefSeq NP_990747.1
UniGene Gga.4418
ProteinModelPortal Q90871
SMR Q90871
STRING 9031.ENSGALP00000009229
PaxDb Q90871
PRIDE Q90871
GeneID 396385
KEGG gga:396385
CTD 3394
eggNOG NOG42878
HOGENOM HOG000010107
HOVERGEN HBG003072
InParanoid Q90871
KO K10155
OrthoDB EOG7CCBR1
PhylomeDB Q90871
TreeFam TF328512
NextBio 20816427
PRO PR:Q90871
Proteomes UP000000539
ExpressionAtlas Q90871
GO GO:0005634
GO:0000975
GO:0003700
GO:0071222
GO:0042742
GO:0042832
GO:0006955
GO:0030099
GO:0044130
GO:0006909
GO:0032729
GO:0032735
GO:0060261
GO:0006351
Gene3D 1.10.10.10
2.60.200.10
InterPro IPR019817
IPR001346
IPR019471
IPR017855
IPR008984
IPR011991
Pfam PF00605
PF10401
PRINTS PR00267
SMART SM00348
SUPFAM SSF49879
PROSITE PS00601
PS51507

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q02556

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q02556

C

Seeded From UniProt

complete

involved_in

GO:0071346

cellular response to interferon-gamma

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q02556

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q02556

P

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q02556

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1096873
MGI:MGI:1859179
MGI:MGI:96395
MGI:MGI:96590
PANTHER:PTN000942746
RGD:2920
UniProtKB:O14896
UniProtKB:P10914
UniProtKB:P14316
UniProtKB:Q02556
UniProtKB:Q13568
UniProtKB:Q14653
UniProtKB:Q15306
UniProtKB:Q92985
ZFIN:ZDB-GENE-041114-13
ZFIN:ZDB-GENE-070912-330

C

Seeded From UniProt

complete

involved_in

GO:0002376

immune system process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1096873
MGI:MGI:1350924
MGI:MGI:1859179
MGI:MGI:1859212
MGI:MGI:96395
MGI:MGI:96590
PANTHER:PTN000942747
UniProtKB:P10914
UniProtKB:P14316
UniProtKB:Q02556
UniProtKB:Q92985
ZFIN:ZDB-GENE-040718-367
ZFIN:ZDB-GENE-070912-330

P

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1859212
PANTHER:PTN000942746
UniProtKB:P10914
UniProtKB:P14316
UniProtKB:Q02556
UniProtKB:Q14653
UniProtKB:Q15306
UniProtKB:Q92985
ZFIN:ZDB-GENE-070912-330

F

Seeded From UniProt

complete

involved_in

GO:0071222

cellular response to lipopolysaccharide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0044130

negative regulation of growth of symbiont in host

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0042832

defense response to protozoan

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0042742

defense response to bacterium

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0032735

positive regulation of interleukin-12 production

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0032729

positive regulation of interferon-gamma production

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0030099

myeloid cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0009617

response to bacterium

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0006955

immune response

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0006909

phagocytosis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

F

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P23611
ensembl:ENSMUSP00000040245

P

Seeded From UniProt

complete

involved_in

GO:0071346

cellular response to interferon-gamma

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02556
ensembl:ENSP00000268638

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02556
ensembl:ENSP00000268638

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02556
ensembl:ENSP00000268638

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02556
ensembl:ENSP00000268638

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02556
ensembl:ENSP00000268638

C

Seeded From UniProt

complete

enables

GO:0001227

DNA-binding transcription repressor activity, RNA polymerase II-specific

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02556
ensembl:ENSP00000268638

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02556
ensembl:ENSP00000268638

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q02556
ensembl:ENSP00000268638

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR019471
InterPro:IPR019817

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR019471
InterPro:IPR019817

P

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001346

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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