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HUMAN:TCFL5
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | TCFL5 (synonyms: CHA, E2BP1) | |
| Protein Name(s) | Transcription factor-like 5 protein
Cha transcription factor HPV-16 E2-binding protein 1 E2BP-1 | |
| External Links | ||
| UniProt | Q9UL49 | |
| EMBL | AJ271337 AF070992 AL035669 AB012124 | |
| CCDS | CCDS13506.1 | |
| RefSeq | NP_006593.2 | |
| UniGene | Hs.126248 | |
| ProteinModelPortal | Q9UL49 | |
| SMR | Q9UL49 | |
| BioGrid | 115955 | |
| STRING | 9606.ENSP00000334294 | |
| PhosphoSite | Q9UL49 | |
| DMDM | 166214983 | |
| MaxQB | Q9UL49 | |
| PaxDb | Q9UL49 | |
| PRIDE | Q9UL49 | |
| Ensembl | ENST00000335351 | |
| GeneID | 10732 | |
| KEGG | hsa:10732 | |
| UCSC | uc002ydo.3 | |
| CTD | 10732 | |
| GeneCards | GC20M061472 | |
| H-InvDB | HIX0203065 | |
| HGNC | HGNC:11646 | |
| HPA | HPA055223 | |
| MIM | 604745 | |
| neXtProt | NX_Q9UL49 | |
| PharmGKB | PA36398 | |
| eggNOG | NOG28448 | |
| GeneTree | ENSGT00390000002821 | |
| HOGENOM | HOG000231268 | |
| HOVERGEN | HBG067309 | |
| InParanoid | Q9UL49 | |
| KO | K09092 | |
| OMA | DRFNSIQ | |
| OrthoDB | EOG7CK36S | |
| PhylomeDB | Q9UL49 | |
| TreeFam | TF336112 | |
| SignaLink | Q9UL49 | |
| ChiTaRS | TCFL5 | |
| GenomeRNAi | 10732 | |
| NextBio | 40740 | |
| PRO | PR:Q9UL49 | |
| Proteomes | UP000005640 | |
| Bgee | Q9UL49 | |
| CleanEx | HS_TCFL5 | |
| ExpressionAtlas | Q9UL49 | |
| Genevestigator | Q9UL49 | |
| GO | GO:0001673 GO:0005634 GO:0003677 GO:0003700 GO:0030154 GO:0007275 GO:0045595 GO:0042127 GO:0006355 GO:0007283 GO:0006366 | |
| Gene3D | 4.10.280.10 | |
| InterPro | IPR011598 | |
| Pfam | PF00010 | |
| SMART | SM00353 | |
| SUPFAM | SSF47459 | |
| PROSITE | PS50888 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000255 |
match to sequence model evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0005556 |
multiple sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001227 |
DNA-binding transcription repressor activity, RNA polymerase II-specific |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
|
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_regulation_target:(NCBI_Gene:914) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
has_regulation_target:(NCBI_Gene:914) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045595 |
regulation of cell differentiation |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042127 |
regulation of cell population proliferation |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007283 |
spermatogenesis |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007283 |
spermatogenesis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001034971 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001034971 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001034971 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2672878 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q32NY8 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0001673 |
male germ cell nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q32NY8 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007283 |
spermatogenesis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046983 |
protein dimerization activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006366 |
transcription by RNA polymerase II |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007283 |
spermatogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Rodríguez, CI et al. (2003) Cha, a basic helix-loop-helix transcription factor involved in the regulation of upstream stimulatory factor activity. J. Biol. Chem. 278 43135-45 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Maruyama, O et al. (1998) Cloning of TCFL5 encoding a novel human basic helix-loop-helix motif protein that is specifically expressed in primary spermatocytes at the pachytene stage. Cytogenet. Cell Genet. 82 41-5 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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