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MOUSE:MYEF2

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Myef2 (synonyms: Kiaa1341, Mef2)
Protein Name(s) Myelin expression factor 2

MEF-2 MyEF-2

External Links
UniProt Q8C854
EMBL AK048404
AK129336
BC060946
AF483504
AF483505
U13262
CCDS CCDS50690.1
CCDS50691.1
PIR A56704
RefSeq NP_001155889.1
XP_006498946.1
XP_006498947.1
UniGene Mm.18535
Mm.455632
ProteinModelPortal Q8C854
SMR Q8C854
BioGrid 201640
IntAct Q8C854
MINT MINT-4118183
PhosphoSite Q8C854
MaxQB Q8C854
PaxDb Q8C854
PRIDE Q8C854
Ensembl ENSMUST00000061419
ENSMUST00000067780
ENSMUST00000110501
ENSMUST00000152367
GeneID 17876
KEGG mmu:17876
UCSC uc008mbw.2
uc008mby.2
uc012cdb.1
CTD 50804
MGI MGI:104592
eggNOG COG0724
GeneTree ENSGT00410000025635
HOGENOM HOG000231932
HOVERGEN HBG054880
InParanoid Q8C854
OMA NSSCTIS
OrthoDB EOG7ZSHSK
PhylomeDB Q8C854
TreeFam TF313406
NextBio 292661
PRO PR:Q8C854
Proteomes UP000000589
UP000000589
Bgee Q8C854
ExpressionAtlas Q8C854
Genevestigator Q8C854
GO GO:0005634
GO:0000166
GO:0003723
GO:0000978
GO:0001078
GO:0000122
Gene3D 3.30.70.330
InterPro IPR012677
IPR000504
Pfam PF00076
SMART SM00360
PROSITE PS50102

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0001227

DNA-binding transcription repressor activity, RNA polymerase II-specific

PMID:7539003[1]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_at:(SO:0001952)

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:7539003[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:7539003[1]

ECO:0000314

direct assay evidence used in manual assertion

P

has_regulation_target:(NCBI_Gene:17196)

Seeded From UniProt

complete

involved_in

GO:2000815

regulation of mRNA stability involved in response to oxidative stress

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001493199
PomBase:SPAC12G12.03
PomBase:SPBC16A3.18

P

Seeded From UniProt

complete

part_of

GO:1990904

ribonucleoprotein complex

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267790
PANTHER:PTN000543776

C

Seeded From UniProt

complete

part_of

GO:0071014

post-mRNA release spliceosomal complex

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001493199
PomBase:SPAC12G12.03
PomBase:SPBC16A3.18

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267790
PANTHER:PTN000543776
PomBase:SPAC12G12.03
PomBase:SPBC16A3.18
SGD:S000000147
SGD:S000004949

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267790
PANTHER:PTN000543776
SGD:S000000517
SGD:S000004949
UniProtKB:Q9P2K5

C

Seeded From UniProt

complete

enables

GO:0003729

mRNA binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0267790
PANTHER:PTN000543776
SGD:S000000517

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104592
PANTHER:PTN000543816

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9P2K5

C

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034632

F

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000504
InterPro:IPR035979

F

Seeded From UniProt

complete

enables

GO:0003697

single-stranded DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034632

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Haas, S et al. (1995) Identification of a sequence-specific single-stranded DNA binding protein that suppresses transcription of the mouse myelin basic protein gene. J. Biol. Chem. 270 12503-10 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page