MOUSE:PRDM1

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Prdm1 (synonyms: Blimp1)
Protein Name(s)	PR domain zinc finger protein 1 B lymphocyte-induced maturation protein 1 Blimp-1 Beta-interferon gene positive regulatory domain I-binding factor PR domain-containing protein 1
External Links
UniProt	Q60636
EMBL	U08185 AF305539 AF305534 AF305535 AF305536 AF305537 AF305538 AK077622 AK149344 BC129801
CCDS	CCDS23825.2
PIR	A53503
RefSeq	NP_031574.2 XP_006512565.1 XP_006512566.1 XP_006512568.1
UniGene	Mm.4800
ProteinModelPortal	Q60636
SMR	Q60636
BioGrid	198355
IntAct	Q60636
STRING	10090.ENSMUSP00000101129
PhosphoSite	Q60636
PaxDb	Q60636
PRIDE	Q60636
DNASU	12142
Ensembl	ENSMUST00000039174 ENSMUST00000105490
GeneID	12142
KEGG	mmu:12142
UCSC	uc007ezu.2 uc007ezv.2
CTD	639
MGI	MGI:99655
eggNOG	COG5048
GeneTree	ENSGT00740000115517
HOGENOM	HOG000059670
HOVERGEN	HBG053670
InParanoid	Q60636
OMA	TGYKTLP
OrthoDB	EOG7060Q3
PhylomeDB	Q60636
TreeFam	TF316545
NextBio	280465
PRO	PR:Q60636
Proteomes	UP000000589
Bgee	Q60636
CleanEx	MM_PRDM1
Genevestigator	Q60636
GO	GO:0005737 GO:0005634 GO:0042826 GO:0046872 GO:0008168 GO:0043565 GO:0045165 GO:0001892 GO:0042462 GO:0007281 GO:0001701 GO:0060576 GO:0001893 GO:0030889 GO:0010629 GO:0031665 GO:0000122 GO:0045579 GO:0010628 GO:0009791 GO:0006351 GO:0060707
Gene3D	3.30.160.60
InterPro	IPR016608 IPR001214 IPR007087 IPR015880 IPR013087
PANTHER	PTHR11389:SF339
Pfam	PF00856
PIRSF	PIRSF013212
SMART	SM00317 SM00355
PROSITE	PS50280 PS00028 PS50157

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0046549	retinal cone cell development	PMID:20463215^[1]	ECO:0000315			P		Fig 2j+l	complete
	GO:0046548	retinal rod cell development	PMID:20463215^[1]	ECO:0000315			P		Fig 2h+w	complete
	GO:0046532	regulation of photoreceptor cell differentiation	PMID:20463215^[1]	ECO:0000315			P		Fig 3F and reduced numbers of differentiated photoreceptors in blimp1 knockouts	complete
	GO:0010629	negative regulation of gene expression	PMID:20463215^[1]	ECO:0000315			P		Fig 6a	complete
	GO:0010628	positive regulation of gene expression	PMID:20463215^[1]	ECO:0000315			P		Fig 6b	complete
	GO:0032582	negative regulation of gene-specific transcription	PMID:20463215^[1]	ECO:0000314			P		Fig 6d	complete
	GO:0003677	DNA binding	PMID:20463215^[1]	ECO:0000314			F		Fig 6e	complete
	GO:0016566	specific transcriptional repressor activity	PMID:20463215^[1]	ECO:0000314			F		Fig 6d	complete
	GO:0060040	retinal bipolar neuron differentiation	PMID:20463215^[1]	ECO:0000315			P		Fig 7b+d	complete
enables	GO:1990841	promoter-specific chromatin binding	PMID:27102484^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0033082	regulation of extrathymic T cell differentiation	PMID:27102484^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051136	regulation of NK T cell differentiation	PMID:27102484^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032823	regulation of natural killer cell differentiation	PMID:27102484^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045165	cell fate commitment	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99655 PANTHER:PTN000421213	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2384854 MGI:MGI:99655 PANTHER:PTN001818762 UniProtKB:Q9NQV7 UniProtKB:Q9NQX1 UniProtKB:Q9Y462	F		Seeded From UniProt	complete
enables	GO:0042826	histone deacetylase binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99655 PANTHER:PTN000421213	F		Seeded From UniProt	complete
enables	GO:0031490	chromatin DNA binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3588194 PANTHER:PTN001818762	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99655 PANTHER:PTN000421213 UniProtKB:F1NKI2 UniProtKB:O75626 WB:WBGene00003847	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0035625 MGI:MGI:1920093 MGI:MGI:1930121 MGI:MGI:2448528 MGI:MGI:2684938 MGI:MGI:3588194 MGI:MGI:99655 PANTHER:PTN001818762 RGD:1594531 RGD:619929 UniProtKB:Q13029 UniProtKB:Q9H4Q4 UniProtKB:Q9NQX1 UniProtKB:Q9Y462 WB:WBGene00003847	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001818762 ZFIN:ZDB-GENE-030131-2193	F		Seeded From UniProt	complete
enables	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3588194 PANTHER:PTN001818762 UniProtKB:Q13029	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1990654	sebum secreting cell proliferation	PMID:16901790^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060976	coronary vasculature development	PMID:25807483^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060707	trophoblast giant cell differentiation	PMID:22987638^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:5439582	P	occurs_in:(EMAPA:16042)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060576	intestinal epithelial cell development	PMID:21670299^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605483 MGI:MGI:3605621	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048844	artery morphogenesis	PMID:24821700^[8]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:98493	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048844	artery morphogenesis	PMID:24821700^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605483 MGI:MGI:3605621	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045165	cell fate commitment	PMID:15937476^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3586884	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045165	cell fate commitment	PMID:15750184^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605483	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042462	eye photoreceptor cell development	PMID:20463215^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605621,MGI:MGI:4881674	P	occurs_in:(EMAPA:17168) results_in_development_of:(CL:0000287)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042462	eye photoreceptor cell development	PMID:20463215^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605621,MGI:MGI:3608904	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042127	regulation of cell population proliferation	PMID:24821700^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605483 MGI:MGI:3605621	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035904	aorta development	PMID:25807483^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010629	negative regulation of gene expression	PMID:21670299^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605483 MGI:MGI:3605621	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010628	positive regulation of gene expression	PMID:18622394^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0009791	post-embryonic development	PMID:21670299^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605483 MGI:MGI:3605621	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007281	germ cell development	PMID:19578360^[12]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1890546	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75626	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16901790^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002559) part_of:(EMAPA:18771)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0003281	ventricular septum development	PMID:25807483^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0003279	cardiac septum development	PMID:25807483^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0003170	heart valve development	PMID:25807483^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001893	maternal placenta development	PMID:15750184^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605483	P	results_in_development_of:(EMAPA:35689)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001892	embryonic placenta development	PMID:15750184^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605483	P	results_in_development_of:(EMAPA:16042)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001763	morphogenesis of a branching structure	PMID:24821700^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605483 MGI:MGI:3605621	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001701	in utero embryonic development	PMID:15750184^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3605483	P		Seeded From UniProt	complete
enables	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75626	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75626	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:20463215^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:88401)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75626	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O75626 ensembl:ENSP00000358092	C		Seeded From UniProt	complete
enables	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O75626 ensembl:ENSP00000358092	F		Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O75626 ensembl:ENSP00000358092	F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O75626 ensembl:ENSP00000358092	P		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013087	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045579	positive regulation of B cell differentiation	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0042826	histone deacetylase binding	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030889	negative regulation of B cell proliferation	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
NOT\|acts_upstream_of_or_within	GO:0045579	positive regulation of B cell differentiation	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0042826	histone deacetylase binding	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030889	negative regulation of B cell proliferation	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:18845144^[13]	ECO:0000314	direct assay evidence used in manual assertion		P	has_regulation_target:(MGI:MGI:99655)	Seeded From UniProt	complete
involved_in	GO:0002376	immune system process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0391	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
involved_in	GO:0032259	methylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0489	P		Seeded From UniProt	complete
involved_in	GO:0002250	adaptive immune response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1064	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0008168	methyltransferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0489	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0045087	innate immune response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0399	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 Katoh, K et al. (2010) Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development. J. Neurosci. 30 6515-26 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Mackay, LK et al. (2016) Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes. Science 352 459-63 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^4.0 ^4.1 Horsley, V et al. (2006) Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell 126 597-609 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 Li, Y et al. (2015) Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature 521 520-4 PubMed GONUTS page
↑ Mould, A et al. (2012) Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta. Genes Dev. 26 2063-74 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Harper, J et al. (2011) The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc. Natl. Acad. Sci. U.S.A. 108 10585-90 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 Vincent, SD et al. (2014) Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo. Hum. Mol. Genet. 23 5087-101 PubMed GONUTS page
↑ Ohinata, Y et al. (2005) Blimp1 is a critical determinant of the germ cell lineage in mice. Nature 436 207-13 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 ^10.3 Vincent, SD et al. (2005) The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse. Development 132 1315-25 PubMed GONUTS page
↑ Yamaji, M et al. (2008) Critical function of Prdm14 for the establishment of the germ cell lineage in mice. Nat. Genet. 40 1016-22 PubMed GONUTS page
↑ West, JA et al. (2009) A role for Lin28 in primordial germ-cell development and germ-cell malignancy. Nature 460 909-13 PubMed GONUTS page
↑ ^13.00 ^13.01 ^13.02 ^13.03 ^13.04 ^13.05 ^13.06 ^13.07 ^13.08 ^13.09 ^13.10 Schmidt, D et al. (2008) Blimp-1Deltaexon7: a naturally occurring Blimp-1 deletion mutant with auto-regulatory potential. Exp. Cell Res. 314 3614-27 PubMed GONUTS page

[PMID:20463215-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 Katoh, K et al. (2010) Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development. J. Neurosci. 30 6515-26 PubMed GONUTS page

[PMID:27102484-2] 2.0 ^2.1 ^2.2 ^2.3 Mackay, LK et al. (2016) Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes. Science 352 459-63 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:16901790-4] 4.0 ^4.1 Horsley, V et al. (2006) Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell 126 597-609 PubMed GONUTS page

[PMID:25807483-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 Li, Y et al. (2015) Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature 521 520-4 PubMed GONUTS page

[PMID:22987638-6] Mould, A et al. (2012) Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta. Genes Dev. 26 2063-74 PubMed GONUTS page

[PMID:21670299-7] 7.0 ^7.1 ^7.2 Harper, J et al. (2011) The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc. Natl. Acad. Sci. U.S.A. 108 10585-90 PubMed GONUTS page

[PMID:24821700-8] 8.0 ^8.1 ^8.2 ^8.3 Vincent, SD et al. (2014) Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo. Hum. Mol. Genet. 23 5087-101 PubMed GONUTS page

[PMID:15937476-9] Ohinata, Y et al. (2005) Blimp1 is a critical determinant of the germ cell lineage in mice. Nature 436 207-13 PubMed GONUTS page

[PMID:15750184-10] 10.0 ^10.1 ^10.2 ^10.3 Vincent, SD et al. (2005) The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse. Development 132 1315-25 PubMed GONUTS page

[PMID:18622394-11] Yamaji, M et al. (2008) Critical function of Prdm14 for the establishment of the germ cell lineage in mice. Nat. Genet. 40 1016-22 PubMed GONUTS page

[PMID:19578360-12] West, JA et al. (2009) A role for Lin28 in primordial germ-cell development and germ-cell malignancy. Nature 460 909-13 PubMed GONUTS page

[PMID:18845144-13] 13.00 ^13.01 ^13.02 ^13.03 ^13.04 ^13.05 ^13.06 ^13.07 ^13.08 ^13.09 ^13.10 Schmidt, D et al. (2008) Blimp-1Deltaexon7: a naturally occurring Blimp-1 deletion mutant with auto-regulatory potential. Exp. Cell Res. 314 3614-27 PubMed GONUTS page

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MOUSE:PRDM1

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