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CHICK:EGR1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) EGR1 (synonyms: ZENK)
Protein Name(s) Early growth response protein 1

EGR-1 Zinc finger protein ZENK

External Links
UniProt O73691
EMBL AF026082
UniGene Gga.4922
ProteinModelPortal O73691
SMR O73691
STRING 9031.ENSGALP00000012417
eggNOG COG5048
InParanoid O73691
Proteomes UP000000539
ExpressionAtlas O73691
GO GO:0005654
GO:0003677
GO:0046872
GO:0001077
GO:0000977
GO:0043565
GO:0003700
GO:0030509
GO:0071480
GO:0070498
GO:0090090
GO:0000122
GO:0045893
GO:0042981
GO:0033233
GO:0061418
GO:0009749
GO:0032868
GO:0035914
GO:0030217
Gene3D 3.30.160.60
InterPro IPR021839
IPR007087
IPR015880
IPR013087
Pfam PF11914
SMART SM00355
PROSITE PS00028
PS50157

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08046

P

Seeded From UniProt

complete

involved_in

GO:0032922

circadian regulation of gene expression

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08046

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P18146

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P18146

C

Seeded From UniProt

complete

enables

GO:1990841

promoter-specific chromatin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

enables

GO:0044729

hemi-methylated DNA-binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

enables

GO:0010385

double-stranded methylated DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

involved_in

GO:0070498

interleukin-1-mediated signaling pathway

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

enables

GO:0035035

histone acetyltransferase binding

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

involved_in

GO:0033233

regulation of protein sumoylation

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

P

Seeded From UniProt

complete

involved_in

GO:0006366

transcription by RNA polymerase II

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

C

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

enables

GO:0000976

transcription regulatory region sequence-specific DNA binding

PMID:9501495[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

involved_in

GO:0098759

cellular response to interleukin-8

PMID:9501495[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P18146

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08046

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P18146

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P18146

F

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1338056
MGI:MGI:1342287
MGI:MGI:1354948
MGI:MGI:2153049
MGI:MGI:2153568
MGI:MGI:2181068
MGI:MGI:98968
PANTHER:PTN001145452
RGD:3738
UniProtKB:A0A1D8PNL1
UniProtKB:Q02446
UniProtKB:Q7RTV3
ZFIN:ZDB-GENE-021115-9

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0043364
FB:FBgn0261434
FB:FBgn0263239
MGI:MGI:1101353
MGI:MGI:1277166
MGI:MGI:1333856
MGI:MGI:1338056
MGI:MGI:1342287
MGI:MGI:1342772
MGI:MGI:1346318
MGI:MGI:1929988
MGI:MGI:1932575
MGI:MGI:2153568
MGI:MGI:95295
MGI:MGI:95296
MGI:MGI:98372
MGI:MGI:98968
PANTHER:PTN001145452
RGD:1306768
RGD:2544
RGD:3738
RGD:3741
RGD:3974
RGD:621445
RGD:621652
RGD:62389
UniProtKB:A0A0B4KHC8
UniProtKB:A0A0G2K5M1
UniProtKB:P18146
UniProtKB:P19544
UniProtKB:Q02086
UniProtKB:Q13351
UniProtKB:Q13886
UniProtKB:Q7RTV3
UniProtKB:Q8TDD2
UniProtKB:Q99612
UniProtKB:Q9UIH9
WB:WBGene00007772
WB:WBGene00012735

C

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001145452
UniProtKB:O14901
UniProtKB:Q9Y5W3
WB:WBGene00012735
ZFIN:ZDB-GENE-021115-9

F

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013087

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:9501495[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0048511

rhythmic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0090

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 Long, KD & Salbaum, JM (1998) Evolutionary conservation of the immediate-early gene ZENK. Mol. Biol. Evol. 15 284-92 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page