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Category:GO:0004888 ! transmembrane signaling receptor activity

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DAG for GO:0004888id: GO:0004888

name: transmembrane signaling receptor activity
namespace: molecular_function
alt_id: GO:0004926
alt_id: GO:0099600
def: "Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction." [GOC:go_curators, Wikipedia:Transmembrane_receptor]
comment: This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.
synonym: "transmembrane receptor activity" BROAD [GOC:bf, GOC:signaling]
synonym: "transmembrane signalling receptor activity" EXACT [GOC:mah]
is_a: GO:0038023 ! signaling receptor activity

AmiGO <GOterm>GO:0004888</GOterm>
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