MOUSE:CD44

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Cd44 (synonyms: Ly-24)
Protein Name(s)	CD44 antigen Extracellular matrix receptor III ECMR-III GP90 lymphocyte homing/adhesion receptor HUTCH-I Hermes antigen Hyaluronate receptor Lymphocyte antigen 24 Ly-24 Phagocytic glycoprotein 1 PGP-1 Phagocytic glycoprotein I PGP-I
External Links
UniProt	P15379
EMBL	X66084 X66083 X66082 X66081 M30655 M27129 M27130 AJ251594 BC005676 AK045226 J05163 X69724 L13611 U57610 U57611 U57612 U57612
PIR	A34424 A37009 B44355 D44355 S30397
RefSeq	NP_001034240.1 NP_001171256.1 NP_001171257.1 NP_001171258.1 NP_033981.2
UniGene	Mm.423621
PDB	2JCP 2JCQ 2JCR 2ZPY 4MRD 4MRE 4MRF 4MRG 4MRH 4NP2 4NP3
PDBsum	2JCP 2JCQ 2JCR 2ZPY 4MRD 4MRE 4MRF 4MRG 4MRH 4NP2 4NP3
ProteinModelPortal	P15379
SMR	P15379
DIP	DIP-29095N
IntAct	P15379
PhosphoSite	P15379
MaxQB	P15379
PaxDb	P15379
PRIDE	P15379
GeneID	12505
KEGG	mmu:12505
CTD	960
MGI	MGI:88338
eggNOG	NOG41023
HOVERGEN	HBG003850
InParanoid	P15379
KO	K06256
ChiTaRS	Cd44
EvolutionaryTrace	P15379
NextBio	281466
PRO	PR:P15379
Proteomes	UP000000589
CleanEx	MM_CD44
Genevestigator	P15379
GO	GO:0016323 GO:0009986 GO:0009897 GO:0016021 GO:0035692 GO:0005886 GO:0005540 GO:0060442 GO:0001658 GO:0007155 GO:0019221 GO:0043518 GO:1902166 GO:0002906 GO:0002821 GO:0070374 GO:0010628 GO:0033138 GO:0050731 GO:0016055 GO:0002246
Gene3D	3.10.100.10
InterPro	IPR016186 IPR016187 IPR001231 IPR000538
Pfam	PF00193
PRINTS	PR00658 PR01265
SMART	SM00445
SUPFAM	SSF56436
PROSITE	PS01241 PS50963

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0044425	cell adhesion	PMID:7528778^[1]	ECO:0000314			P		CD44 is a transmembrane glycoprotein expressed in leukocytes.	complete CACAO 3563
part_of	GO:0005902	microvillus	PMID:9472040^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
part_of	GO:0031258	lamellipodium membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
involved_in	GO:2000392	regulation of lamellipodium morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
involved_in	GO:0044319	wound healing, spreading of cells	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
enables	GO:0005114	type II transforming growth factor beta receptor binding	PMID:25065622^[3]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q64729	F	occurs_in:(CL:0000902) has_input:(UniProtKB:P04202) occurs_at:(GO:0005886)	Seeded From UniProt	complete
involved_in	GO:0050728	negative regulation of inflammatory response	PMID:25065622^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0000902)	Seeded From UniProt	complete
involved_in	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	PMID:25065622^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_agent:(CL:0000902)	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	PMID:25065622^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_regulation_target:(UniProtKB:Q99JB6) occurs_in:(CL:0000902) has_direct_input:(UniProtKB:O08573)\|has_regulation_target(UniProtKB:Q99JB6) occurs_in:(CL:0000084) has_direct_input:(UniProtKB:O08573)	Seeded From UniProt	complete
involved_in	GO:0045590	negative regulation of regulatory T cell differentiation	PMID:25065622^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:25065622^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0035692	macrophage migration inhibitory factor receptor complex	PMID:17045821^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0035692	macrophage migration inhibitory factor receptor complex	PMID:18056708^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	PMID:17045821^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PMID:17045821^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	PMID:17045821^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	PMID:17045821^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0033138	positive regulation of peptidyl-serine phosphorylation	PMID:17045821^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
contributes_to	GO:0019955	cytokine binding	PMID:18056708^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
contributes_to	GO:0004896	cytokine receptor activity	PMID:17045821^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0002906	negative regulation of mature B cell apoptotic process	PMID:18056708^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0002821	positive regulation of adaptive immune response	PMID:18056708^[5]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88338 PANTHER:PTN000027499 UniProtKB:P16070	P		Seeded From UniProt	complete
part_of	GO:0035692	macrophage migration inhibitory factor receptor complex	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88338 PANTHER:PTN000027499 UniProtKB:P16070	C		Seeded From UniProt	complete
part_of	GO:0016323	basolateral plasma membrane	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88338 PANTHER:PTN000027499 RGD:2307 UniProtKB:F1SGT4	C		Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88338 PANTHER:PTN000027499 RGD:2307	P		Seeded From UniProt	complete
involved_in	GO:0006954	inflammatory response	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000027499 RGD:2307	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2136348 MGI:MGI:88338 PANTHER:PTN000812484 UniProtKB:F1SGT4 UniProtKB:P16070	C		Seeded From UniProt	complete
enables	GO:0005540	hyaluronic acid binding	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2136348 MGI:MGI:88338 PANTHER:PTN000812485 UniProtKB:P16070	F		Seeded From UniProt	complete
contributes_to	GO:0004896	cytokine receptor activity	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88338 PANTHER:PTN000027499 UniProtKB:P16070	F		Seeded From UniProt	complete
enables	GO:0004888	transmembrane signaling receptor activity	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2136348 PANTHER:PTN000812484	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034116	positive regulation of heterotypic cell-cell adhesion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0033674	positive regulation of kinase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0033138	positive regulation of peptidyl-serine phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0033031	positive regulation of neutrophil apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	P		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	C		Seeded From UniProt	complete
part_of	GO:0031258	lamellipodium membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031175	neuron projection development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030214	hyaluronan catabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0016477	cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0016477	cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	P		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	C		Seeded From UniProt	complete
part_of	GO:0016323	basolateral plasma membrane	PMID:10027409^[7]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:35778) part_of:(CL:0000066)	Seeded From UniProt	complete
part_of	GO:0016323	basolateral plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0016055	Wnt signaling pathway	PMID:19056892^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010628	positive regulation of gene expression	PMID:9847236^[9]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:99604	P	has_regulation_target:(MGI:MGI:894670)\|has_regulation_target:(MGI:MGI:1306803)	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:9324354^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:17716972^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:9133426^[12]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:8769481^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:8043862^[14]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000839)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:7584142^[15]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:35523) part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:7538697^[16]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:22072979^[17]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:21708977^[18]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:21508411^[19]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:21460847^[20]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:20711497^[21]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:19934022^[22]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:19723499^[23]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:19008373^[24]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:18767) part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:18958875^[25]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000893)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:17082577^[26]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:16973387^[27]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000624)\|part_of:(CL:0000625)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:16301745^[28]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000624)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:16203996^[29]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:16177108^[30]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:15843532^[31]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:15728238^[32]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:15477346^[33]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000624)\|part_of:(CL:0000625)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:15294943^[34]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)\|part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:14764662^[35]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000623)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:14609575^[36]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:10943842^[37]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16846) part_of:(CL:0000081)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:10848813^[38]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:10704459^[39]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:10072077^[40]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007155	cell adhesion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007155	cell adhesion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:9374396^[41]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:32290)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:18085615^[42]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:18852) part_of:(CL:0000066)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	C		Seeded From UniProt	complete
enables	GO:0005540	hyaluronic acid binding	PMID:10926769^[43]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0005540	hyaluronic acid binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	F		Seeded From UniProt	complete
enables	GO:0005154	epidermal growth factor receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	F		Seeded From UniProt	complete
contributes_to	GO:0004896	cytokine receptor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002246	wound healing involved in inflammatory response	PMID:11935029^[44]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181292	P	has_participant:(EMAPA:16728)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001658	branching involved in ureteric bud morphogenesis	PMID:10926769^[43]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001558	regulation of cell growth	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000392	regulation of lamellipodium morphogenesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1900625	positive regulation of monocyte aggregation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0070487	monocyte aggregation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060442	branching involved in prostate gland morphogenesis	PMID:9374396^[41]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0051219	phosphoprotein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0044344	cellular response to fibroblast growth factor stimulus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0044319	wound healing, spreading of cells	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043066	negative regulation of apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042110	T cell activation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	P		Seeded From UniProt	complete
part_of	GO:0035692	macrophage migration inhibitory factor receptor complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16070	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034238	macrophage fusion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2307	P		Seeded From UniProt	complete
involved_in	GO:0019221	cytokine-mediated signaling pathway	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004896	P		Seeded From UniProt	complete
involved_in	GO:0019221	cytokine-mediated signaling pathway	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004896	P		Seeded From UniProt	complete
involved_in	GO:0019221	cytokine-mediated signaling pathway	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004896	P		Seeded From UniProt	complete
enables	GO:0005540	hyaluronic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000538	F		Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000538 InterPro:IPR001231	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001231	C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007155	cell adhesion	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005540	hyaluronic acid binding	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007155	cell adhesion	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007155	cell adhesion	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005540	hyaluronic acid binding	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007155	cell adhesion	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005540	hyaluronic acid binding	PMID:1469058^[45]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0130	P		Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005902	microvillus	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0293	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ Puré, E et al. (1995) Defective phosphorylation and hyaluronate binding of CD44 with point mutations in the cytoplasmic domain. J. Exp. Med. 181 55-62 PubMed GONUTS page
↑ Yonemura, S et al. (1998) Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2. J. Cell Biol. 140 885-95 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Wu, C et al. (2014) Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells. Immunity 41 270-82 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 Shi, X et al. (2006) CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity 25 595-606 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 Gore, Y et al. (2008) Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex. J. Biol. Chem. 283 2784-92 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 ^6.7 ^6.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Wielenga, VJ et al. (1999) Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway. Am. J. Pathol. 154 515-23 PubMed GONUTS page
↑ Miranda-Carboni, GA et al. (2008) A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. Genes Dev. 22 3121-34 PubMed GONUTS page
↑ Tucker, AS et al. (1999) Conserved regulation of mesenchymal gene expression by Fgf-8 in face and limb development. Development 126 221-8 PubMed GONUTS page
↑ Yoder, MC et al. (1997) Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity 7 335-44 PubMed GONUTS page
↑ Liu, L et al. (2007) Tetraspanin CD151 promotes cell migration by regulating integrin trafficking. J. Biol. Chem. 282 31631-42 PubMed GONUTS page
↑ Mendiratta, SK et al. (1997) CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 6 469-77 PubMed GONUTS page
↑ Hazenbos, WL et al. (1996) Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice. Immunity 5 181-8 PubMed GONUTS page
↑ Coombe, DR et al. (1994) Mac-1 (CD11b/CD18) and CD45 mediate the adhesion of hematopoietic progenitor cells to stromal cell elements via recognition of stromal heparan sulfate. Blood 84 739-52 PubMed GONUTS page
↑ Willerford, DM et al. (1995) Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 3 521-30 PubMed GONUTS page
↑ Bendelac, A et al. (1995) CD1 recognition by mouse NK1+ T lymphocytes. Science 268 863-5 PubMed GONUTS page
↑ Nowell, CS et al. (2011) Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence. PLoS Genet. 7 e1002348 PubMed GONUTS page
↑ Crippa, S et al. (2011) miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors. J. Cell Biol. 193 1197-212 PubMed GONUTS page
↑ Hu, MG et al. (2011) CDK6 kinase activity is required for thymocyte development. Blood 117 6120-31 PubMed GONUTS page
↑ Motomura, Y et al. (2011) The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat. Immunol. 12 450-9 PubMed GONUTS page
↑ Dumitriu, B et al. (2010) Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions. PLoS ONE 5 e12088 PubMed GONUTS page
↑ Hosoya, T et al. (2009) GATA-3 is required for early T lineage progenitor development. J. Exp. Med. 206 2987-3000 PubMed GONUTS page
↑ Terauchi, M et al. (2009) T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling. Cell Metab. 10 229-40 PubMed GONUTS page
↑ Abe, J et al. (2008) Increased Foxp3(+) CD4(+) regulatory T cells with intact suppressive activity but altered cellular localization in murine lupus. Am. J. Pathol. 173 1682-92 PubMed GONUTS page
↑ Jia, J et al. (2008) E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene. Eur. J. Immunol. 38 2806-20 PubMed GONUTS page
↑ Kim, PJ et al. (2006) GATA-3 regulates the development and function of invariant NKT cells. J. Immunol. 177 6650-9 PubMed GONUTS page
↑ Marie, JC et al. (2006) Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity 25 441-54 PubMed GONUTS page
↑ Chen, Z et al. (2005) Where CD4+CD25+ T reg cells impinge on autoimmune diabetes. J. Exp. Med. 202 1387-97 PubMed GONUTS page
↑ Chen, Z et al. (2005) How defects in central tolerance impinge on a deficiency in regulatory T cells. Proc. Natl. Acad. Sci. U.S.A. 102 14735-40 PubMed GONUTS page
↑ Nishimura, H et al. (2005) A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8+ T cells. J. Immunol. 175 4627-34 PubMed GONUTS page
↑ Cheung, H et al. (2005) Accessory protein-like is essential for IL-18-mediated signaling. J. Immunol. 174 5351-7 PubMed GONUTS page
↑ Mandal, M et al. (2005) The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. J. Exp. Med. 201 603-14 PubMed GONUTS page
↑ Li, O et al. (2004) CD24 expression on T cells is required for optimal T cell proliferation in lymphopenic host. J. Exp. Med. 200 1083-9 PubMed GONUTS page
↑ Kang, J et al. (2004) STAT5 is required for thymopoiesis in a development stage-specific manner. J. Immunol. 173 2307-14 PubMed GONUTS page
↑ Hamerman, JA et al. (2004) Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor. J. Immunol. 172 2001-5 PubMed GONUTS page
↑ Matsuzaki, J et al. (2003) Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo. Cell. Immunol. 224 98-105 PubMed GONUTS page
↑ Tamura, K et al. (2000) Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102 221-31 PubMed GONUTS page
↑ Kina, T et al. (2000) The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage. Br. J. Haematol. 109 280-7 PubMed GONUTS page
↑ Kennedy, MK et al. (2000) Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 191 771-80 PubMed GONUTS page
↑ Moriggl, R et al. (1999) Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 10 249-59 PubMed GONUTS page
↑ ^41.0 ^41.1 Gakunga, P et al. (1997) Hyaluronan is a prerequisite for ductal branching morphogenesis. Development 124 3987-97 PubMed GONUTS page
↑ Preston, SL et al. (2008) The development of duodenal microadenomas in FAP patients: the human correlate of the Min mouse. J. Pathol. 214 294-301 PubMed GONUTS page
↑ ^43.0 ^43.1 Pohl, M et al. (2000) Role of hyaluronan and CD44 in in vitro branching morphogenesis of ureteric bud cells. Dev. Biol. 224 312-25 PubMed GONUTS page
↑ Teder, P et al. (2002) Resolution of lung inflammation by CD44. Science 296 155-8 PubMed GONUTS page
↑ ^45.00 ^45.01 ^45.02 ^45.03 ^45.04 ^45.05 ^45.06 ^45.07 ^45.08 ^45.09 ^45.10 He, Q et al. (1992) Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition. J. Cell Biol. 119 1711-9 PubMed GONUTS page

[PMID:7528778-1] Puré, E et al. (1995) Defective phosphorylation and hyaluronate binding of CD44 with point mutations in the cytoplasmic domain. J. Exp. Med. 181 55-62 PubMed GONUTS page

[PMID:9472040-2] Yonemura, S et al. (1998) Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2. J. Cell Biol. 140 885-95 PubMed GONUTS page

[PMID:25065622-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Wu, C et al. (2014) Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells. Immunity 41 270-82 PubMed GONUTS page

[PMID:17045821-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 Shi, X et al. (2006) CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity 25 595-606 PubMed GONUTS page

[PMID:18056708-5] 5.0 ^5.1 ^5.2 ^5.3 Gore, Y et al. (2008) Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex. J. Biol. Chem. 283 2784-92 PubMed GONUTS page

[PMID:21873635-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 ^6.7 ^6.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10027409-7] Wielenga, VJ et al. (1999) Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway. Am. J. Pathol. 154 515-23 PubMed GONUTS page

[PMID:19056892-8] Miranda-Carboni, GA et al. (2008) A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. Genes Dev. 22 3121-34 PubMed GONUTS page

[PMID:9847236-9] Tucker, AS et al. (1999) Conserved regulation of mesenchymal gene expression by Fgf-8 in face and limb development. Development 126 221-8 PubMed GONUTS page

[PMID:9324354-10] Yoder, MC et al. (1997) Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity 7 335-44 PubMed GONUTS page

[PMID:17716972-11] Liu, L et al. (2007) Tetraspanin CD151 promotes cell migration by regulating integrin trafficking. J. Biol. Chem. 282 31631-42 PubMed GONUTS page

[PMID:9133426-12] Mendiratta, SK et al. (1997) CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 6 469-77 PubMed GONUTS page

[PMID:8769481-13] Hazenbos, WL et al. (1996) Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice. Immunity 5 181-8 PubMed GONUTS page

[PMID:8043862-14] Coombe, DR et al. (1994) Mac-1 (CD11b/CD18) and CD45 mediate the adhesion of hematopoietic progenitor cells to stromal cell elements via recognition of stromal heparan sulfate. Blood 84 739-52 PubMed GONUTS page

[PMID:7584142-15] Willerford, DM et al. (1995) Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 3 521-30 PubMed GONUTS page

[PMID:7538697-16] Bendelac, A et al. (1995) CD1 recognition by mouse NK1+ T lymphocytes. Science 268 863-5 PubMed GONUTS page

[PMID:22072979-17] Nowell, CS et al. (2011) Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence. PLoS Genet. 7 e1002348 PubMed GONUTS page

[PMID:21708977-18] Crippa, S et al. (2011) miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors. J. Cell Biol. 193 1197-212 PubMed GONUTS page

[PMID:21508411-19] Hu, MG et al. (2011) CDK6 kinase activity is required for thymocyte development. Blood 117 6120-31 PubMed GONUTS page

[PMID:21460847-20] Motomura, Y et al. (2011) The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat. Immunol. 12 450-9 PubMed GONUTS page

[PMID:20711497-21] Dumitriu, B et al. (2010) Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions. PLoS ONE 5 e12088 PubMed GONUTS page

[PMID:19934022-22] Hosoya, T et al. (2009) GATA-3 is required for early T lineage progenitor development. J. Exp. Med. 206 2987-3000 PubMed GONUTS page

[PMID:19723499-23] Terauchi, M et al. (2009) T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling. Cell Metab. 10 229-40 PubMed GONUTS page

[PMID:19008373-24] Abe, J et al. (2008) Increased Foxp3(+) CD4(+) regulatory T cells with intact suppressive activity but altered cellular localization in murine lupus. Am. J. Pathol. 173 1682-92 PubMed GONUTS page

[PMID:18958875-25] Jia, J et al. (2008) E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene. Eur. J. Immunol. 38 2806-20 PubMed GONUTS page

[PMID:17082577-26] Kim, PJ et al. (2006) GATA-3 regulates the development and function of invariant NKT cells. J. Immunol. 177 6650-9 PubMed GONUTS page

[PMID:16973387-27] Marie, JC et al. (2006) Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity 25 441-54 PubMed GONUTS page

[PMID:16301745-28] Chen, Z et al. (2005) Where CD4+CD25+ T reg cells impinge on autoimmune diabetes. J. Exp. Med. 202 1387-97 PubMed GONUTS page

[PMID:16203996-29] Chen, Z et al. (2005) How defects in central tolerance impinge on a deficiency in regulatory T cells. Proc. Natl. Acad. Sci. U.S.A. 102 14735-40 PubMed GONUTS page

[PMID:16177108-30] Nishimura, H et al. (2005) A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8+ T cells. J. Immunol. 175 4627-34 PubMed GONUTS page

[PMID:15843532-31] Cheung, H et al. (2005) Accessory protein-like is essential for IL-18-mediated signaling. J. Immunol. 174 5351-7 PubMed GONUTS page

[PMID:15728238-32] Mandal, M et al. (2005) The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. J. Exp. Med. 201 603-14 PubMed GONUTS page

[PMID:15477346-33] Li, O et al. (2004) CD24 expression on T cells is required for optimal T cell proliferation in lymphopenic host. J. Exp. Med. 200 1083-9 PubMed GONUTS page

[PMID:15294943-34] Kang, J et al. (2004) STAT5 is required for thymopoiesis in a development stage-specific manner. J. Immunol. 173 2307-14 PubMed GONUTS page

[PMID:14764662-35] Hamerman, JA et al. (2004) Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor. J. Immunol. 172 2001-5 PubMed GONUTS page

[PMID:14609575-36] Matsuzaki, J et al. (2003) Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo. Cell. Immunol. 224 98-105 PubMed GONUTS page

[PMID:10943842-37] Tamura, K et al. (2000) Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102 221-31 PubMed GONUTS page

[PMID:10848813-38] Kina, T et al. (2000) The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage. Br. J. Haematol. 109 280-7 PubMed GONUTS page

[PMID:10704459-39] Kennedy, MK et al. (2000) Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 191 771-80 PubMed GONUTS page

[PMID:10072077-40] Moriggl, R et al. (1999) Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 10 249-59 PubMed GONUTS page

[PMID:9374396-41] 41.0 ^41.1 Gakunga, P et al. (1997) Hyaluronan is a prerequisite for ductal branching morphogenesis. Development 124 3987-97 PubMed GONUTS page

[PMID:18085615-42] Preston, SL et al. (2008) The development of duodenal microadenomas in FAP patients: the human correlate of the Min mouse. J. Pathol. 214 294-301 PubMed GONUTS page

[PMID:10926769-43] 43.0 ^43.1 Pohl, M et al. (2000) Role of hyaluronan and CD44 in in vitro branching morphogenesis of ureteric bud cells. Dev. Biol. 224 312-25 PubMed GONUTS page

[PMID:11935029-44] Teder, P et al. (2002) Resolution of lung inflammation by CD44. Science 296 155-8 PubMed GONUTS page

[PMID:1469058-45] 45.00 ^45.01 ^45.02 ^45.03 ^45.04 ^45.05 ^45.06 ^45.07 ^45.08 ^45.09 ^45.10 He, Q et al. (1992) Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition. J. Cell Biol. 119 1711-9 PubMed GONUTS page

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