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CHICK:GBRG4

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) GABRG4
Protein Name(s) Gamma-aminobutyric acid receptor subunit gamma-4

GABA(A) receptor subunit gamma-4

External Links
UniProt P34904
EMBL X73533
PIR S38296
RefSeq NP_990576.1
UniGene Gga.692
ProteinModelPortal P34904
STRING 9031.ENSGALP00000011763
PaxDb P34904
Ensembl ENSGALT00000011777
GeneID 396173
KEGG gga:396173
CTD 2564
eggNOG NOG238757
GeneTree ENSGT00760000119010
HOGENOM HOG000231337
HOVERGEN HBG051707
InParanoid P34904
KO K05186
OMA FFCCIED
PhylomeDB P34904
NextBio 20816227
PRO PR:P34904
Proteomes UP000000539
GO GO:0030054
GO:0034707
GO:0045211
GO:0005254
GO:0005230
GO:0004890
GO:0007214
Gene3D 2.70.170.10
InterPro IPR006028
IPR005437
IPR006202
IPR006201
IPR006029
IPR018000
PANTHER PTHR18945
Pfam PF02931
PF02932
PRINTS PR00253
PR01620
PR00252
SUPFAM SSF63712
SSF90112
TIGRFAMs TIGR00860
PROSITE PS00236

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:1904315

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95613
PANTHER:PTN000436343

F

Seeded From UniProt

complete

part_of

GO:1902711

GABA-A receptor complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95623
PANTHER:PTN001055383
UniProtKB:P14867
UniProtKB:P47869
UniProtKB:P78334

C

Seeded From UniProt

complete

involved_in

GO:1902476

chloride transmembrane transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95623
PANTHER:PTN001055383
UniProtKB:P14867
UniProtKB:P47869

P

Seeded From UniProt

complete

part_of

GO:0098794

postsynapse

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95614
PANTHER:PTN000436343

C

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95613
PANTHER:PTN000436343

P

Seeded From UniProt

complete

involved_in

GO:0051932

synaptic transmission, GABAergic

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000436343
RGD:61855
RGD:61861
RGD:61966

P

Seeded From UniProt

complete

involved_in

GO:0050877

nervous system process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:87888
PANTHER:PTN000434994
UniProtKB:P11230
UniProtKB:P17787
UniProtKB:P43681

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95747
PANTHER:PTN000434994
UniProtKB:G5EDF1
UniProtKB:P11230
WB:WBGene00006765
WB:WBGene00006774

C

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95747
PANTHER:PTN000434994
RGD:2351
RGD:621544
WB:WBGene00000042
WB:WBGene00002974
WB:WBGene00006765
WB:WBGene00006774

C

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:87885
MGI:MGI:87887
MGI:MGI:87888
MGI:MGI:87890
MGI:MGI:87891
MGI:MGI:87892
MGI:MGI:87893
MGI:MGI:87894
MGI:MGI:87895
MGI:MGI:95747
MGI:MGI:95751
MGI:MGI:99779
PANTHER:PTN000434994
RGD:2348
UniProtKB:P02708
UniProtKB:P23415

P

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95613
PANTHER:PTN000434994
UniProtKB:P23416
UniProtKB:P36544
UniProtKB:Q401N2
WB:WBGene00000055
WB:WBGene00002974
WB:WBGene00006797

P

Seeded From UniProt

complete

part_of

GO:0032590

dendrite membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000436343
RGD:61856
RGD:61966

C

Seeded From UniProt

complete

enables

GO:0022851

GABA-gated chloride ion channel activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000436343
RGD:61861
UniProtKB:P14867
UniProtKB:P47869
UniProtKB:P78334

F

Seeded From UniProt

complete

contributes_to

GO:0008503

benzodiazepine receptor activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001055383
RGD:61861
UniProtKB:P47869

F

Seeded From UniProt

complete

involved_in

GO:0007268

chemical synaptic transmission

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003011
FB:FBgn0086778
MGI:MGI:103156
MGI:MGI:95613
MGI:MGI:95623
MGI:MGI:95747
PANTHER:PTN000434994
RGD:2648
RGD:61859
RGD:61901
UniProtKB:P48167
WB:WBGene00000050
WB:WBGene00000054

P

Seeded From UniProt

complete

involved_in

GO:0007214

gamma-aminobutyric acid signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95623
PANTHER:PTN001055383
RGD:68320
UniProtKB:P47869

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000434994
UniProtKB:P11230
UniProtKB:P17787
UniProtKB:P30926
UniProtKB:P32297
UniProtKB:P36544
UniProtKB:P43681
UniProtKB:Q15822

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1861899
MGI:MGI:95623
MGI:MGI:95750
PANTHER:PTN000434994
RGD:2649
RGD:2650
RGD:61855
RGD:61861
RGD:621229
UniProtKB:O75311
UniProtKB:P23415
UniProtKB:P23416
UniProtKB:P28472
UniProtKB:P48167
UniProtKB:Q9UGM1
WB:WBGene00000955
WB:WBGene00001133
WB:WBGene00001591
WB:WBGene00001592

C

Seeded From UniProt

complete

enables

GO:0005254

chloride channel activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95623
PANTHER:PTN001055383
RGD:61966
RGD:621735

F

Seeded From UniProt

complete

enables

GO:0005237

inhibitory extracellular ligand-gated ion channel activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001055383
RGD:61861

F

Seeded From UniProt

complete

contributes_to

GO:0005230

extracellular ligand-gated ion channel activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000434994
WB:WBGene00000043
WB:WBGene00001512
WB:WBGene00003386
WB:WBGene00006774
WB:WBGene00012857
WB:WBGene00017375

F

Seeded From UniProt

complete

contributes_to

GO:0004890

GABA-A receptor activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95623
PANTHER:PTN001055383
RGD:2648
RGD:61859
RGD:61861
RGD:61966
RGD:621732
RGD:621735
RGD:68320

F

Seeded From UniProt

complete

involved_in

GO:2001226

negative regulation of chloride transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78334
ensembl:ENSP00000359353

P

Seeded From UniProt

complete

part_of

GO:1902711

GABA-A receptor complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78334
ensembl:ENSP00000359353

C

Seeded From UniProt

complete

enables

GO:0022851

GABA-gated chloride ion channel activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P78334
ensembl:ENSP00000359353

F

Seeded From UniProt

complete

enables

GO:0004888

transmembrane signaling receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006028
InterPro:IPR006201

F

Seeded From UniProt

complete

enables

GO:0004890

GABA-A receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005437

F

Seeded From UniProt

complete

enables

GO:0005216

ion channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006028
InterPro:IPR006201

F

Seeded From UniProt

complete

enables

GO:0005230

extracellular ligand-gated ion channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006202
InterPro:IPR036734

F

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006029
InterPro:IPR006202
InterPro:IPR036719
InterPro:IPR036734

P

Seeded From UniProt

complete

involved_in

GO:0006821

chloride transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005437

P

Seeded From UniProt

complete

involved_in

GO:0007214

gamma-aminobutyric acid signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005437

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005437
InterPro:IPR006028
InterPro:IPR006029
InterPro:IPR006201
InterPro:IPR006202
InterPro:IPR036719
InterPro:IPR036734

C

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006028
InterPro:IPR006201

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

involved_in

GO:0006821

chloride transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0869

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

enables

GO:0005254

chloride channel activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0869

F

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0628
UniProtKB-SubCell:SL-0219

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0034707

chloride channel complex

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0869

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page