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CAEEL:CUP4
Contents
| Species (Taxon ID) | Caenorhabditis elegans. (6239) | |
| Gene Name(s) | cup-4 | |
| Protein Name(s) | Acetylcholine receptor-like protein cup-4
Coelomocyte uptake defective protein 4 | |
| External Links | ||
| UniProt | P34271 | |
| EMBL | AY611497 FO080276 | |
| PIR | S44741 | |
| RefSeq | NP_498710.2 | |
| UniGene | Cel.19985 | |
| ProteinModelPortal | P34271 | |
| SMR | P34271 | |
| STRING | 6239.C02C2.3 | |
| PaxDb | P34271 | |
| PRIDE | P34271 | |
| EnsemblMetazoa | C02C2.3 | |
| GeneID | 176104 | |
| KEGG | cel:CELE_C02C2.3 | |
| UCSC | C02C2.3 | |
| CTD | 176104 | |
| WormBase | C02C2.3 | |
| eggNOG | NOG325377 | |
| GeneTree | ENSGT00390000014985 | |
| HOGENOM | HOG000112082 | |
| InParanoid | P34271 | |
| OMA | SAHVIIQ | |
| OrthoDB | EOG7QNVQV | |
| PhylomeDB | P34271 | |
| Reactome | REACT_210579 | |
| NextBio | 891132 | |
| Proteomes | UP000001940 | |
| GO | GO:0031410 GO:0030659 GO:0016021 GO:0015464 GO:0005230 GO:0005216 GO:0006897 GO:0034220 GO:0030100 GO:0007268 | |
| Gene3D | 2.70.170.10 | |
| InterPro | IPR006202 IPR006201 IPR018000 | |
| PANTHER | PTHR18945 | |
| Pfam | PF02931 | |
| SUPFAM | SSF63712 | |
| PROSITE | PS00236 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005216 |
ion channel activity |
ECO:0000269 |
F |
Figure 3D suggests resistance to oxidative resistance at the membrane level. Also, the author states "These findings indicate that NLP-7 and CUP-4 function in the same pathway under DR. Other SKN-1-dependent pathways might be activated by dietary restriction (DR)" . |
complete | |||||
|
involved_in |
GO:0008340 |
determination of adult lifespan |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008340 |
determination of adult lifespan |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901046 |
positive regulation of oviposition |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008340 |
determination of adult lifespan |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008340 |
determination of adult lifespan |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061771 |
response to caloric restriction |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901562 |
response to paraquat |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901562 |
response to paraquat |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061771 |
response to caloric restriction |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006897 |
endocytosis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030659 |
cytoplasmic vesicle membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030100 |
regulation of endocytosis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015464 |
acetylcholine receptor activity |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050877 |
nervous system process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:87888 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0045202 |
synapse |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:95747 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043005 |
neuron projection |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:95747 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042391 |
regulation of membrane potential |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:87885 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0034220 |
ion transmembrane transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:95613 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007268 |
chemical synaptic transmission |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003011 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000434994 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1861899 |
C |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0005230 |
extracellular ligand-gated ion channel activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000434994 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004888 |
transmembrane signaling receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005216 |
ion channel activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005230 |
extracellular ligand-gated ion channel activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006811 |
ion transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034220 |
ion transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005216 |
ion channel activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006897 |
endocytosis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006811 |
ion transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030659 |
cytoplasmic vesicle membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Park, SK et al. (2010) Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans. FASEB J. 24 383-92 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Patton, A et al. (2005) Endocytosis function of a ligand-gated ion channel homolog in Caenorhabditis elegans. Curr. Biol. 15 1045-50 PubMed GONUTS page
- ↑ Fares, H & Greenwald, I (2001) Genetic analysis of endocytosis in Caenorhabditis elegans: coelomocyte uptake defective mutants. Genetics 159 133-45 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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