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This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

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CHICK:A1YV56

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) TLR3 (ECO:0000313 with EMBL:ABL74502.1)
Protein Name(s) Toll-like receptor 3 (ECO:0000313 with EMBL:ABL74502.1)
External Links
UniProt A1YV56
EMBL EF137861
UniGene Gga.19919
ProteinModelPortal A1YV56
SMR A1YV56
STRING 9031.ENSGALP00000021914
PaxDb A1YV56
eggNOG NOG265249
HOGENOM HOG000251618
HOVERGEN HBG023181
GO GO:0016021
GO:0003725
GO:0004888
GO:0051607
GO:0045087
GO:0002756
GO:0032722
GO:0050729
GO:0043330
GO:0034138
Gene3D 3.40.50.10140
InterPro IPR000483
IPR001611
IPR003591
IPR000372
IPR000157
IPR027173
PANTHER PTHR24365:SF5
Pfam PF13855
PF01582
SMART SM00369
SM00082
SM00013
SM00255
SUPFAM SSF52200
PROSITE PS51450
PS50104

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003725

double-stranded RNA binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

F

complete

GO:0001819

positive regulation of cytokine production

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

P

Seeded From UniProt

complete

GO:0004872

receptor activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0675

F

complete

GO:0002376

immune system process

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0391

P

Seeded From UniProt

complete

GO:0004888

transmembrane receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000157

F

complete

GO:0002756

MyD88-independent toll-like receptor signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

P

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

C

complete

GO:0003725

double-stranded RNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

F

Seeded From UniProt

complete

GO:0007165

signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000157

P

complete

GO:0004888

transmembrane signaling receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

F

Seeded From UniProt

complete

GO:0007252

I-kappaB phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

P

complete

GO:0007165

signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000157

P

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

complete

GO:0016020

membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

complete

GO:0016021

integral component of membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

C

Seeded From UniProt

complete

GO:0031224

intrinsic to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000157

C

complete

GO:0016021

integral component of membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

GO:0032722

positive regulation of chemokine production

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

P

complete

GO:0032722

positive regulation of chemokine production

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

P

Seeded From UniProt

complete

GO:0032755

positive regulation of interleukin-6 production

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

P

complete

GO:0034138

toll-like receptor 3 signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

P

Seeded From UniProt

complete

GO:0032757

positive regulation of interleukin-8 production

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

P

complete

GO:0043330

response to exogenous dsRNA

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

P

Seeded From UniProt

complete

GO:0034123

positive regulation of toll-like receptor signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

P

complete

GO:0045087

innate immune response

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

P

Seeded From UniProt

complete

GO:0042346

positive regulation of NF-kappaB import into nucleus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

P

complete

GO:0045087

innate immune response

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0399

P

Seeded From UniProt

complete

GO:0045078

positive regulation of interferon-gamma biosynthetic process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

P

complete

GO:0050729

positive regulation of inflammatory response

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

P

Seeded From UniProt

complete

GO:0045087

innate immune response

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000157

P

complete

GO:0051607

defense response to virus

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027173

P

Seeded From UniProt

complete

GO:0045356

positive regulation of interferon-alpha biosynthetic process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

P

complete

GO:0045359

positive regulation of interferon-beta biosynthetic process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000296795

P

complete

Notes

References

See Help:References for how to manage references in GONUTS.