HUMAN:NRX2A

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	NRXN2 (synonyms: KIAA0921)
Protein Name(s)	Neurexin-2 Neurexin II-alpha Neurexin-2-alpha
External Links
UniProt	Q9P2S2
EMBL	AB035266 AB023138 AC044790 BC150275
CCDS	CCDS31597.1 CCDS8077.1
RefSeq	NP_055895.1 NP_620060.1
UniGene	Hs.372938
ProteinModelPortal	Q9P2S2
SMR	Q9P2S2
BioGrid	114780
IntAct	Q9P2S2
MINT	MINT-1381393
PhosphoSite	Q9P2S2
DMDM	17369343
PaxDb	Q9P2S2
PRIDE	Q9P2S2
Ensembl	ENST00000265459 ENST00000377551 ENST00000377559
GeneID	9379
KEGG	hsa:9379
UCSC	uc001oas.3 uc021qkw.1
CTD	9379
GeneCards	GC11M064373
HGNC	HGNC:8009
MIM	600566
neXtProt	NX_Q9P2S2
PharmGKB	PA31787
eggNOG	NOG302266
GeneTree	ENSGT00760000118991
HOGENOM	HOG000230481
HOVERGEN	HBG052670
InParanoid	Q9P2S2
KO	K07377
OMA	RFRGAIR
PhylomeDB	Q9P2S2
TreeFam	TF321302
ChiTaRS	NRXN2
GenomeRNAi	9379
NextBio	35140
Proteomes	UP000005640
Bgee	Q9P2S2
CleanEx	HS_NRXN2
ExpressionAtlas	Q9P2S2
Genevestigator	Q9P2S2
GO	GO:0016021 GO:0005246 GO:0050839 GO:0046872 GO:0097109 GO:0030534 GO:0097116 GO:0097118 GO:0007158 GO:0007269 GO:0097119 GO:0097104 GO:0035176 GO:0007416 GO:0007268 GO:0042297 GO:0071625
Gene3D	2.60.120.200
InterPro	IPR013320 IPR000742 IPR001791 IPR003585 IPR027160 IPR027789
PANTHER	PTHR10127:SF593
Pfam	PF02210 PF01034
SMART	SM00294 SM00181 SM00282
SUPFAM	SSF49899
PROSITE	PS50026 PS50025

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0050839	cell adhesion molecule binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	F		Seeded From UniProt	complete
enables	GO:0004888	transmembrane signaling receptor activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	F		Seeded From UniProt	complete
involved_in	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	P		Seeded From UniProt	complete
involved_in	GO:0097104	postsynaptic membrane assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	P		Seeded From UniProt	complete
involved_in	GO:0007269	neurotransmitter secretion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	P		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	P		Seeded From UniProt	complete
enables	GO:0097109	neuroligin family protein binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	F		Seeded From UniProt	complete
enables	GO:0005246	calcium channel regulator activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	F		Seeded From UniProt	complete
involved_in	GO:0097119	postsynaptic density protein 95 clustering	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	P		Seeded From UniProt	complete
involved_in	GO:0097116	gephyrin clustering involved in postsynaptic density assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	P		Seeded From UniProt	complete
involved_in	GO:0007416	synapse assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	P		Seeded From UniProt	complete
involved_in	GO:0007268	chemical synaptic transmission	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:E9Q7X7	P		Seeded From UniProt	complete
involved_in	GO:0071625	vocalization behavior	PMID:21424692	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042297	vocal learning	PMID:21424692	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	PMID:21424692	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030534	adult behavior	PMID:21424692	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0007269	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR037440	C		Seeded From UniProt	complete
involved_in	GO:0007158	neuron cell-cell adhesion		ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-6797974 Reactome:R-HSA-6797568 Reactome:R-HSA-6797554 Reactome:R-HSA-6794346	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C		Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0130	P		Seeded From UniProt	complete
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References

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