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DANRE:Q5TZ38

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) No Information Provided.
Protein Name(s) Frizzled homolog 3 (ECO:0000313 with EMBL:AAI63439.1)

Frizzled3a protein (ECO:0000313 with EMBL:BAF36661.1) Transmembrane receptor frizzled-3 (ECO:0000313 with EMBL:ABA86555.1) Uncharacterized protein (ECO:0000313 with Ensembl:ENSDARP00000084982)

External Links
UniProt Q5TZ38
EMBL BX511007
BC163439
BC163452
DQ200953
AB246776
RefSeq NP_001036226.1
UniGene Dr.81883
STRING 7955.ENSDARP00000084982
MEROPS I93.001
Ensembl ENSDART00000090549
GeneID 565921
KEGG dre:565921
CTD 565921
ZFIN ZDB-GENE-990415-225
GeneTree ENSGT00760000118864
HOGENOM HOG000233237
HOVERGEN HBG006977
KO K02329
OMA GNGIHRV
OrthoDB EOG7M3J01
PhylomeDB Q5TZ38
TreeFam TF317907
Reactome REACT_175482
REACT_223798
NextBio 20887926
PRO PR:Q5TZ38
Proteomes UP000000437
GO GO:0045177
GO:0030424
GO:0005737
GO:0030425
GO:0016021
GO:0032589
GO:0043025
GO:0048786
GO:0030165
GO:0042813
GO:0017147
GO:0060070
GO:0033278
GO:0071679
GO:0001736
GO:0021754
GO:0007199
GO:0008406
GO:0042472
GO:0001843
GO:0001944
Gene3D 1.10.2000.10
InterPro IPR000539
IPR015526
IPR020067
IPR026553
IPR017981
PANTHER PTHR11309
PTHR11309:SF22
Pfam PF01534
PF01392
PRINTS PR00489
SMART SM00063
SUPFAM SSF63501
PROSITE PS50038
PS50261

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071679

commissural neuron axon guidance

PMID:23438515[1]

ECO:0000316

genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-070116-1
ZFIN:ZDB-MRPHLNO-120810-2

P

Seeded From UniProt

complete

involved_in

GO:0071679

commissural neuron axon guidance

PMID:27955617[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-GENO-170328-1

P

Seeded From UniProt

complete

involved_in

GO:0071679

commissural neuron axon guidance

PMID:23438515[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-120810-2

P

Seeded From UniProt

complete

involved_in

GO:0033564

anterior/posterior axon guidance

PMID:27955617[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-GENO-170328-1

P

Seeded From UniProt

complete

involved_in

GO:0021754

facial nucleus development

PMID:17079269[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-GENO-070119-5

P

Seeded From UniProt

complete

involved_in

GO:0060070

canonical Wnt signaling pathway

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001085
FB:FBgn0016797
MGI:MGI:108460
MGI:MGI:108520
MGI:MGI:108570
MGI:MGI:108571
MGI:MGI:1196625
PANTHER:PTN000139394
RGD:61916
RGD:71012
UniProtKB:O75084
UniProtKB:Q13467
UniProtKB:Q14332
UniProtKB:Q8N474
UniProtKB:Q9H461
UniProtKB:Q9NPG1
UniProtKB:Q9ULV1
UniProtKB:Q9ULW2
UniProtKB:Q9UP38

P

Seeded From UniProt

complete

enables

GO:0042813

Wnt-activated receptor activity

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001085
FB:FBgn0016797
MGI:MGI:108460
MGI:MGI:108476
MGI:MGI:108520
MGI:MGI:108570
MGI:MGI:1313278
MGI:MGI:1888513
PANTHER:PTN000139394
RGD:628817
RGD:71012
UniProtKB:O60353
UniProtKB:O75084
UniProtKB:Q13467
UniProtKB:Q14332
UniProtKB:Q9H461
UniProtKB:Q9ULV1
UniProtKB:Q9ULW2
UniProtKB:Q9UP38

F

Seeded From UniProt

complete

involved_in

GO:0035567

non-canonical Wnt signaling pathway

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:108570
PANTHER:PTN000139394
UniProtKB:O60353
ZFIN:ZDB-GENE-990415-218

P

Seeded From UniProt

complete

enables

GO:0017147

Wnt-protein binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001085
FB:FBgn0016797
FB:FBgn0027342
FB:FBgn0027343
MGI:MGI:108078
MGI:MGI:108460
MGI:MGI:108474
MGI:MGI:108520
MGI:MGI:108570
MGI:MGI:108571
MGI:MGI:1196625
MGI:MGI:2136761
MGI:MGI:892032
PANTHER:PTN000139394
RGD:621075
RGD:631406
RGD:71017
UniProtKB:O00144
UniProtKB:O75084
UniProtKB:Q13467
UniProtKB:Q6FHJ7
UniProtKB:Q8N474
UniProtKB:Q9NPG1
UniProtKB:Q9UP38

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0016797
MGI:MGI:108075
MGI:MGI:108460
MGI:MGI:108476
MGI:MGI:108520
MGI:MGI:108570
MGI:MGI:108571
MGI:MGI:1313278
PANTHER:PTN000139394
RGD:61916
RGD:628817
RGD:71012
UniProtKB:O00144
UniProtKB:O19116
UniProtKB:O60353
UniProtKB:O75084
UniProtKB:Q14332
UniProtKB:Q99835
UniProtKB:Q9NPG1
UniProtKB:Q9ULV1
WB:WBGene00003006
ZFIN:ZDB-GENE-990415-223

C

Seeded From UniProt

complete

enables

GO:0004888

transmembrane signaling receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017981

F

Seeded From UniProt

complete

involved_in

GO:0007166

cell surface receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000539
InterPro:IPR017981

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000539

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017981

C

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR026553

P

Seeded From UniProt

complete

enables

GO:0042813

Wnt-activated receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR026553

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0879

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Hofmeister, W & Key, B (2013) Frizzled-3a and Wnt-8b genetically interact during forebrain commissural formation in embryonic zebrafish. Brain Res. 1506 25-34 PubMed GONUTS page
  2. 2.0 2.1 Sun, SD et al. (2016) Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance. BMC Neurosci 17 83 PubMed GONUTS page
  3. Wada, H et al. (2006) Frizzled3a and Celsr2 function in the neuroepithelium to regulate migration of facial motor neurons in the developing zebrafish hindbrain. Development 133 4749-59 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page