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HUMAN:CLD3
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | CLDN3 (synonyms: C7orf1, CPETR2) | |
| Protein Name(s) | Claudin-3
Clostridium perfringens enterotoxin receptor 2 CPE-R 2 CPE-receptor 2 Rat ventral prostate.1 protein homolog hRVP1 | |
| External Links | ||
| UniProt | O15551 | |
| EMBL | AF007189 AB000714 BC016056 | |
| CCDS | CCDS5559.1 | |
| RefSeq | NP_001297.1 | |
| UniGene | Hs.647023 | |
| ProteinModelPortal | O15551 | |
| SMR | O15551 | |
| BioGrid | 107757 | |
| MINT | MINT-5003820 | |
| STRING | 9606.ENSP00000378577 | |
| PhosphoSite | O15551 | |
| MaxQB | O15551 | |
| PaxDb | O15551 | |
| PRIDE | O15551 | |
| DNASU | 1365 | |
| Ensembl | ENST00000395145 | |
| GeneID | 1365 | |
| KEGG | hsa:1365 | |
| UCSC | uc003tzg.4 | |
| CTD | 1365 | |
| GeneCards | GC07M073183 | |
| HGNC | HGNC:2045 | |
| HPA | CAB002702 HPA007322 HPA014361 | |
| MIM | 602910 | |
| neXtProt | NX_O15551 | |
| PharmGKB | PA26571 | |
| eggNOG | NOG281814 | |
| HOGENOM | HOG000220937 | |
| HOVERGEN | HBG000643 | |
| InParanoid | O15551 | |
| KO | K06087 | |
| OMA | VPDAQKR | |
| OrthoDB | EOG79KPGQ | |
| PhylomeDB | O15551 | |
| TreeFam | TF331936 | |
| Reactome | REACT_19373 | |
| GeneWiki | CLDN3 | |
| GenomeRNAi | 1365 | |
| NextBio | 5531 | |
| PRO | PR:O15551 | |
| Proteomes | UP000005640 | |
| Bgee | O15551 | |
| CleanEx | HS_CLDN3 | |
| ExpressionAtlas | O15551 | |
| Genevestigator | O15551 | |
| GO | GO:0070062 GO:0016021 GO:0005887 GO:0016328 GO:0005923 GO:0005198 GO:0004888 GO:0016338 GO:0001666 GO:0007165 | |
| InterPro | IPR006187 IPR003549 IPR017974 IPR004031 | |
| PANTHER | PTHR12002 | |
| Pfam | PF00822 | |
| PRINTS | PR01077 PR01378 | |
| PROSITE | PS01346 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005923 |
bicellular tight junction |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051291 |
protein heterooligomerization |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051260 |
protein homooligomerization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070830 |
bicellular tight junction assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005923 |
bicellular tight junction |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0003382 |
epithelial cell morphogenesis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001666 |
response to hypoxia |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045471 |
response to ethanol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63400 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016328 |
lateral plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63400 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005923 |
bicellular tight junction |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63400 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63400 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9Z0G9 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016338 |
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9Z0G9 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016328 |
lateral plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9Z0G9 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016327 |
apicolateral plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9Z0G9 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005923 |
bicellular tight junction |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9Z0G9 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0003382 |
epithelial cell morphogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9Z0G9 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005198 |
structural molecule activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005923 |
bicellular tight junction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004888 |
transmembrane signaling receptor activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030054 |
cell junction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005923 |
bicellular tight junction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Milatz, S et al. (2015) Probing the cis-arrangement of prototype tight junction proteins claudin-1 and claudin-3. Biochem. J. 468 449-58 PubMed GONUTS page
- ↑ Scheurer, SB et al. (2004) Modulation of gene expression by hypoxia in human umbilical cord vein endothelial cells: A transcriptomic and proteomic study. Proteomics 4 1737-60 PubMed GONUTS page
- ↑ Peacock, RE et al. (1997) Analysis of a human gene homologous to rat ventral prostate.1 protein. Genomics 46 443-9 PubMed GONUTS page
- ↑ 4.0 4.1 Katahira, J et al. (1997) Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo. J. Biol. Chem. 272 26652-8 PubMed GONUTS page
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