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MOUSE:ACHB2

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Chrnb2
Protein Name(s) Neuronal acetylcholine receptor subunit beta-2
External Links
UniProt Q9ERK7
EMBL AF299083
AY574267
AK049722
AK051742
AC102392
CH466547
BC065103
CCDS CCDS17515.1
RefSeq NP_033732.2
UniGene Mm.35088
ProteinModelPortal Q9ERK7
SMR Q9ERK7
DIP DIP-48730N
GuidetoPHARMACOLOGY 472
MaxQB Q9ERK7
PaxDb Q9ERK7
PRIDE Q9ERK7
Ensembl ENSMUST00000029562
GeneID 11444
KEGG mmu:11444
UCSC uc008qaa.2
CTD 1141
MGI MGI:87891
eggNOG NOG290206
GeneTree ENSGT00760000118930
HOGENOM HOG000006757
HOVERGEN HBG003756
InParanoid Q9ERK7
KO K04813
OMA FQNYTTN
OrthoDB EOG72JWGV
TreeFam TF315605
Reactome REACT_198583
REACT_198585
REACT_198593
NextBio 278752
PRO PR:Q9ERK7
Proteomes UP000000589
ExpressionAtlas Q9ERK7
Genevestigator Q9ERK7
GO GO:0005892
GO:0030054
GO:0009897
GO:0005886
GO:0045211
GO:0042166
GO:0015464
GO:0004889
GO:0008144
GO:0001508
GO:0008306
GO:0042113
GO:0035095
GO:0006816
GO:0098655
GO:0021955
GO:0021952
GO:0001661
GO:0021771
GO:0007612
GO:0007626
GO:0051899
GO:0007613
GO:0045759
GO:0021631
GO:0030890
GO:0033603
GO:0032226
GO:0051291
GO:0045188
GO:0042320
GO:0048814
GO:0042053
GO:0014059
GO:0042391
GO:0051963
GO:0032225
GO:0042220
GO:0045471
GO:0001666
GO:0035094
GO:0019233
GO:0007605
GO:0006939
GO:0035176
GO:0060084
GO:0007271
GO:0021562
GO:0008542
GO:0007601
Gene3D 1.20.120.370
2.70.170.10
InterPro IPR027361
IPR006202
IPR006201
IPR006029
IPR018000
IPR002394
PANTHER PTHR18945
Pfam PF02931
PF02932
PRINTS PR00254
PR00252
SUPFAM SSF63712
SSF90112
TIGRFAMs TIGR00860
PROSITE PS00236

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0007271

synaptic transmission, cholinergic

PMID:24223920[1]

ECO:0000314

P

Figure 3 suggests that β2nAchR is critical to cholinergic signaling as DHBE, specific antagonist to β2nAchR, blocks nicotine inhibition. Other nonspecific antagonists do not block nicotine inhibition.

complete
CACAO 9244

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:12944511[2]

ECO:0006042

cell fractionation evidence used in manual assertion

P

  • occurs_in:(GO:0098691)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002435)

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:11145999[3]

ECO:0006042

cell fractionation evidence used in manual assertion

P

  • occurs_in:(GO:0098691)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002435)

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:12944511[2]

ECO:0001225

knockout evidence used in manual assertion

P

  • occurs_in:(GO:0098691)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002435)

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:11145999[3]

ECO:0001225

knockout evidence used in manual assertion

P

  • occurs_in:(GO:0098691)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002435)

Seeded From UniProt

complete

enables

GO:1904315

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

PMID:23811311[4]

ECO:0006013

patch-clamp recording evidence used in manual assertion

F

  • occurs_in:(GO:0098981)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002240)

Seeded From UniProt

complete

enables

GO:1904315

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

PMID:23811311[4]

ECO:0001225

knockout evidence used in manual assertion

F

  • occurs_in:(GO:0098981)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002240)

Seeded From UniProt

complete

part_of

GO:0099060

integral component of postsynaptic specialization membrane

PMID:12079404[5]

ECO:0006003

electron microscopy evidence used in manual assertion

C

  • part_of:(GO:0098981)
  • part_of:(UBERON:0000061)
  • part_of:(UBERON:0001989)

Seeded From UniProt

complete

part_of

GO:0099056

integral component of presynaptic membrane

PMID:24607281[6]

ECO:0006042

cell fractionation evidence used in manual assertion

C

  • part_of:(UBERON:0000061)
  • part_of:(UBERON:0002435)

Seeded From UniProt

complete

part_of

GO:0099056

integral component of presynaptic membrane

PMID:24607281[6]

ECO:0000279

western blot evidence used in manual assertion

C

  • part_of:(UBERON:0000061)
  • part_of:(UBERON:0002435)

Seeded From UniProt

complete

part_of

GO:0098981

cholinergic synapse

PMID:23811311[4]

ECO:0006013

patch-clamp recording evidence used in manual assertion

C

part_of:(UBERON:0002240)

Seeded From UniProt

complete

part_of

GO:0098981

cholinergic synapse

PMID:12079404[5]

ECO:0006003

electron microscopy evidence used in manual assertion

C

part_of:(UBERON:0001989)

Seeded From UniProt

complete

part_of

GO:0098981

cholinergic synapse

PMID:23811311[4]

ECO:0001225

knockout evidence used in manual assertion

C

part_of:(UBERON:0002240)

Seeded From UniProt

complete

part_of

GO:0098691

dopaminergic synapse

PMID:12944511[2]

ECO:0006042

cell fractionation evidence used in manual assertion

C

  • part_of:(UBERON:0000061)
  • part_of:(UBERON:0002435)

Seeded From UniProt

complete

part_of

GO:0098691

dopaminergic synapse

PMID:11145999[3]

ECO:0006042

cell fractionation evidence used in manual assertion

C

  • part_of:(UBERON:0000061)
  • part_of:(UBERON:0002435)

Seeded From UniProt

complete

part_of

GO:0098691

dopaminergic synapse

PMID:12944511[2]

ECO:0001225

knockout evidence used in manual assertion

C

  • part_of:(UBERON:0000061)
  • part_of:(UBERON:0002435)

Seeded From UniProt

complete

part_of

GO:0098691

dopaminergic synapse

PMID:11145999[3]

ECO:0001225

knockout evidence used in manual assertion

C

  • part_of:(UBERON:0000061)
  • part_of:(UBERON:0002435)

Seeded From UniProt

complete

involved_in

GO:0050877

nervous system process

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:87888
PANTHER:PTN000434994
UniProtKB:P11230
UniProtKB:P17787
UniProtKB:P43681

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95747
PANTHER:PTN000434994
UniProtKB:G5EDF1
UniProtKB:P11230
WB:WBGene00006765
WB:WBGene00006774

C

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95747
PANTHER:PTN000434994
RGD:2351
RGD:621544
WB:WBGene00000042
WB:WBGene00002974
WB:WBGene00006765
WB:WBGene00006774

C

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:87885
MGI:MGI:87887
MGI:MGI:87888
MGI:MGI:87890
MGI:MGI:87891
MGI:MGI:87892
MGI:MGI:87893
MGI:MGI:87894
MGI:MGI:87895
MGI:MGI:95747
MGI:MGI:95751
MGI:MGI:99779
PANTHER:PTN000434994
RGD:2348
UniProtKB:P02708
UniProtKB:P23415

P

Seeded From UniProt

complete

contributes_to

GO:0042166

acetylcholine binding

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:87890
MGI:MGI:87893
PANTHER:PTN001825425
RGD:2345
RGD:2350
RGD:2351
UniProtKB:P17787

F

Seeded From UniProt

complete

involved_in

GO:0035094

response to nicotine

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:87891
MGI:MGI:87892
PANTHER:PTN001825425
RGD:2345
RGD:2350
UniProtKB:P17787

P

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95613
PANTHER:PTN000434994
UniProtKB:P23416
UniProtKB:P36544
UniProtKB:Q401N2
WB:WBGene00000055
WB:WBGene00002974
WB:WBGene00006797

P

Seeded From UniProt

complete

contributes_to

GO:0015464

acetylcholine receptor activity

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001825425
RGD:2345
UniProtKB:P11230
UniProtKB:P17787
UniProtKB:P30926
UniProtKB:P32297
ZFIN:ZDB-GENE-040808-32
ZFIN:ZDB-GENE-060811-1
ZFIN:ZDB-GENE-070821-4
ZFIN:ZDB-GENE-120809-1

F

Seeded From UniProt

complete

involved_in

GO:0007274

neuromuscular synaptic transmission

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001825425
UniProtKB:P11230

P

Seeded From UniProt

complete

involved_in

GO:0007271

synaptic transmission, cholinergic

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:87887
PANTHER:PTN001825425
RGD:2350
UniProtKB:P11230
ZFIN:ZDB-GENE-030131-3805
ZFIN:ZDB-GENE-070821-4

P

Seeded From UniProt

complete

involved_in

GO:0007268

chemical synaptic transmission

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003011
FB:FBgn0086778
MGI:MGI:103156
MGI:MGI:95613
MGI:MGI:95623
MGI:MGI:95747
PANTHER:PTN000434994
RGD:2648
RGD:61859
RGD:61901
UniProtKB:P48167
WB:WBGene00000050
WB:WBGene00000054

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000434994
UniProtKB:P11230
UniProtKB:P17787
UniProtKB:P30926
UniProtKB:P32297
UniProtKB:P36544
UniProtKB:P43681
UniProtKB:Q15822

P

Seeded From UniProt

complete

part_of

GO:0005892

acetylcholine-gated channel complex

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:106213
MGI:MGI:87887
MGI:MGI:87890
MGI:MGI:87891
MGI:MGI:87893
MGI:MGI:87895
PANTHER:PTN001825425
RGD:2345
RGD:2349
RGD:2350
RGD:2351
RGD:2352
RGD:2353
RGD:2354
RGD:69281
UniProtKB:P11230
UniProtKB:P17787
UniProtKB:P30926
UniProtKB:P32297
ZFIN:ZDB-GENE-040808-32
ZFIN:ZDB-GENE-060811-1

C

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1861899
MGI:MGI:95623
MGI:MGI:95750
PANTHER:PTN000434994
RGD:2649
RGD:2650
RGD:61855
RGD:61861
RGD:621229
UniProtKB:O75311
UniProtKB:P23415
UniProtKB:P23416
UniProtKB:P28472
UniProtKB:P48167
UniProtKB:Q9UGM1
WB:WBGene00000955
WB:WBGene00001133
WB:WBGene00001591
WB:WBGene00001592

C

Seeded From UniProt

complete

contributes_to

GO:0005230

extracellular ligand-gated ion channel activity

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000434994
WB:WBGene00000043
WB:WBGene00001512
WB:WBGene00003386
WB:WBGene00006774
WB:WBGene00012857
WB:WBGene00017375

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1905144

response to acetylcholine

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

P

Seeded From UniProt

complete

enables

GO:1904315

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

F

Seeded From UniProt

complete

part_of

GO:0099060

integral component of postsynaptic specialization membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

C

Seeded From UniProt

complete

part_of

GO:0099056

integral component of presynaptic membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

C

Seeded From UniProt

complete

part_of

GO:0098981

cholinergic synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0095500

acetylcholine receptor signaling pathway

PMID:26276394[8]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0095500

acetylcholine receptor signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060084

synaptic transmission involved in micturition

PMID:10531434[9]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87892

P

occurs_in:(EMAPA:18321)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051963

regulation of synapse assembly

PMID:17301182[10]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2158714

P

  • regulates_o_has_participant:(EMAPA:32869)
  • regulates_o_has_participant:(CL:0000540)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051899

membrane depolarization

PMID:11222635[11]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

  • occurs_in:(EMAPA:16974)
  • occurs_in:(CL:0000700)|occurs_in:(EMAPA:16974)
  • occurs_in:(CL:0000617)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051291

protein heterooligomerization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050890

cognition

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050877

nervous system process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048814

regulation of dendrite morphogenesis

PMID:11027228[12]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2158714

P

  • regulates_o_occurs_in:(EMAPA:35741)
  • regulates_o_occurs_in:(CL:0000740)

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045759

negative regulation of action potential

PMID:15456819[13]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

  • regulates_o_occurs_in:(EMAPA:35478)
  • regulates_o_occurs_in:(CL:0000540)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045471

response to ethanol

PMID:15489024[14]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2158714

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045188

regulation of circadian sleep/wake cycle, non-REM sleep

PMID:15215293[15]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

regulates_o_has_participant:(EMAPA:16894)

Seeded From UniProt

complete

part_of

GO:0044853

plasma membrane raft

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042391

regulation of membrane potential

PMID:15741168[16]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87888

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042391

regulation of membrane potential

PMID:15569257[17]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87888

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042391

regulation of membrane potential

PMID:10531434[9]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87892

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042391

regulation of membrane potential

PMID:9428762[18]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042320

regulation of circadian sleep/wake cycle, REM sleep

PMID:15215293[15]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

regulates_o_has_participant:(EMAPA:16894)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042220

response to cocaine

PMID:11282258[19]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

enables

GO:0042166

acetylcholine binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

F

Seeded From UniProt

complete

enables

GO:0042166

acetylcholine binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042113

B cell activation

PMID:16253349[20]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042113

B cell activation

PMID:15963492[21]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042053

regulation of dopamine metabolic process

PMID:11282258[19]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

regulates_o_occurs_in:(EMAPA:17549)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035176

social behavior

PMID:12876201[22]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035095

behavioral response to nicotine

PMID:17470777[23]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035095

behavioral response to nicotine

PMID:16965547[24]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035095

behavioral response to nicotine

PMID:15464132[25]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035095

behavioral response to nicotine

PMID:12876201[22]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035095

behavioral response to nicotine

PMID:11955523[26]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035095

behavioral response to nicotine

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035094

response to nicotine

PMID:17470777[23]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:99779

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035094

response to nicotine

PMID:15741168[16]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87888

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035094

response to nicotine

PMID:10531434[9]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87892

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035094

response to nicotine

PMID:9428762[18]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035094

response to nicotine

PMID:15489024[14]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2158714

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035094

response to nicotine

PMID:15215293[15]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

has_participant:(EMAPA:16894)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035094

response to nicotine

PMID:10235262[27]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035094

response to nicotine

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035094

response to nicotine

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0033603

positive regulation of dopamine secretion

PMID:9428762[18]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

  • regulates_o_occurs_in:(EMAPA:17549)
  • regulates_o_occurs_in:(CL:0000700)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0033603

positive regulation of dopamine secretion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032226

positive regulation of synaptic transmission, dopaminergic

PMID:15464132[25]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032225

regulation of synaptic transmission, dopaminergic

PMID:16772172[28]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

  • regulates_o_has_participant:(EMAPA:35914)
  • regulates_o_has_participant:(CL:0000700)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030890

positive regulation of B cell proliferation

PMID:15963492[21]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:88336

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030890

positive regulation of B cell proliferation

PMID:11222635[11]

ECO:0000305

curator inference used in manual assertion

GO:0022848

P

Seeded From UniProt

complete

enables

GO:0022848

acetylcholine-gated cation-selective channel activity

PMID:15741168[16]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87888

F

Seeded From UniProt

complete

enables

GO:0022848

acetylcholine-gated cation-selective channel activity

PMID:15569257[17]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87888

F

Seeded From UniProt

complete

enables

GO:0022848

acetylcholine-gated cation-selective channel activity

PMID:11222635[11]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

F

  • occurs_in:(EMAPA:16974)
  • occurs_in:(CL:0000700)|occurs_in:(EMAPA:16974)
  • occurs_in:(CL:0000617)

Seeded From UniProt

complete

enables

GO:0022848

acetylcholine-gated cation-selective channel activity

PMID:9614223[29]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(EMAPA:16894)

Seeded From UniProt

complete

enables

GO:0022848

acetylcholine-gated cation-selective channel activity

PMID:17470777[23]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(EMAPA:35485)|occurs_in:(EMAPA:32789)|occurs_in:(EMAPA:19095)

Seeded From UniProt

complete

enables

GO:0022848

acetylcholine-gated cation-selective channel activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

F

Seeded From UniProt

complete

enables

GO:0022848

acetylcholine-gated cation-selective channel activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0021955

central nervous system neuron axonogenesis

PMID:12097474[30]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2158714

P

  • occurs_in:(EMAPA:35478)
  • occurs_in:(CL:0000540)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0021952

central nervous system projection neuron axonogenesis

PMID:15608630[31]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2158714

P

  • occurs_in:(EMAPA:35478)
  • occurs_in:(CL:0000117)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0021952

central nervous system projection neuron axonogenesis

PMID:14687550[32]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

  • occurs_in:(EMAPA:35478)
  • occurs_in:(CL:0000117)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0021952

central nervous system projection neuron axonogenesis

PMID:11344259[33]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

  • occurs_in:(EMAPA:35478)
  • occurs_in:(CL:0000740)|occurs_in:(EMAPA:32869)
  • occurs_in:(CL:0000740)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0021771

lateral geniculate nucleus development

PMID:12097474[30]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2158714

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0021631

optic nerve morphogenesis

PMID:12097474[30]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2158714

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0021631

optic nerve morphogenesis

PMID:11344259[33]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0021562

vestibulocochlear nerve development

PMID:15788760[34]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

results_in_development_of:(EMAPA:17572)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0019233

sensory perception of pain

PMID:10235262[27]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926251

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

C

Seeded From UniProt

complete

enables

GO:0015464

acetylcholine receptor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0014059

regulation of dopamine secretion

PMID:12944511[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

  • regulates_o_occurs_in:(EMAPA:17549)
  • regulates_o_occurs_in:(CL:0000700)

Seeded From UniProt

complete

part_of

GO:0009897

external side of plasma membrane

PMID:15963492[21]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:18767)
  • part_of:(CL:0000236)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0008542

visual learning

PMID:12876201[22]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0008542

visual learning

PMID:10064590[35]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0008542

visual learning

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0008306

associative learning

PMID:15541879[36]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:99779

P

Seeded From UniProt

complete

enables

GO:0008144

drug binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007626

locomotory behavior

PMID:9428762[18]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007613

memory

PMID:7870173[37]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007613

memory

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007612

learning

PMID:11044747[38]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007612

learning

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007605

sensory perception of sound

PMID:15788760[34]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

has_participant:(EMAPA:17572)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007601

visual perception

PMID:15456819[13]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007601

visual perception

PMID:11344259[33]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007271

synaptic transmission, cholinergic

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007165

signal transduction

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006939

smooth muscle contraction

PMID:10531434[9]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87892

P

occurs_in:(EMAPA:35448)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006816

calcium ion transport

PMID:15569257[17]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87888

P

Seeded From UniProt

complete

part_of

GO:0005892

acetylcholine-gated channel complex

PMID:26276394[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005892

acetylcholine-gated channel complex

PMID:12944511[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:17549)

Seeded From UniProt

complete

part_of

GO:0005892

acetylcholine-gated channel complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

C

Seeded From UniProt

complete

part_of

GO:0005892

acetylcholine-gated channel complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:26276394[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:15741168[16]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:19474315[39]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P12390

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2350

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001666

response to hypoxia

PMID:15450117[40]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001666

response to hypoxia

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P17787

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001661

conditioned taste aversion

PMID:11955523[26]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001508

action potential

PMID:10531434[9]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:87892

P

  • occurs_in:(EMAPA:18441)
  • regulates_o_occurs_in:(CL:0000540)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001508

action potential

PMID:10235262[27]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:1926253

P

  • occurs_in:(EMAPA:35720)
  • regulates_o_occurs_in:(CL:0000850)|occurs_in(EMAPA:17540)
  • regulates_o_occurs_in:(CL:0000117)

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:1904315

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:1904315

P

Seeded From UniProt

complete

involved_in

GO:0060078

regulation of postsynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:1904315

P

Seeded From UniProt

complete

involved_in

GO:0060079

excitatory postsynaptic potential

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060079

excitatory postsynaptic potential

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060079

excitatory postsynaptic potential

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060079

excitatory postsynaptic potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060079

excitatory postsynaptic potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060079

excitatory postsynaptic potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060079

excitatory postsynaptic potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060079

excitatory postsynaptic potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060079

excitatory postsynaptic potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:0060079

excitatory postsynaptic potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0022848

P

Seeded From UniProt

complete

involved_in

GO:1905144

response to acetylcholine

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

P

Seeded From UniProt

complete

enables

GO:1904315

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

F

Seeded From UniProt

complete

part_of

GO:0099060

integral component of postsynaptic specialization membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

C

Seeded From UniProt

complete

part_of

GO:0099056

integral component of presynaptic membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

C

Seeded From UniProt

complete

part_of

GO:0098981

cholinergic synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

C

Seeded From UniProt

complete

involved_in

GO:0095500

acetylcholine receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

P

Seeded From UniProt

complete

involved_in

GO:0051291

protein heterooligomerization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

P

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

F

Seeded From UniProt

complete

part_of

GO:0044853

plasma membrane raft

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

C

Seeded From UniProt

complete

enables

GO:0042166

acetylcholine binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

F

Seeded From UniProt

complete

involved_in

GO:0035094

response to nicotine

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

P

Seeded From UniProt

complete

involved_in

GO:0033603

positive regulation of dopamine secretion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

P

Seeded From UniProt

complete

enables

GO:0022848

acetylcholine-gated cation-selective channel activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

C

Seeded From UniProt

complete

enables

GO:0008144

drug binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

F

Seeded From UniProt

complete

involved_in

GO:0007271

synaptic transmission, cholinergic

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

P

Seeded From UniProt

complete

part_of

GO:0005892

acetylcholine-gated channel complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P12390
ensembl:ENSRNOP00000028200

C

Seeded From UniProt

complete

involved_in

GO:0050890

cognition

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

P

Seeded From UniProt

complete

involved_in

GO:0050877

nervous system process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

P

Seeded From UniProt

complete

enables

GO:0042166

acetylcholine binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

F

Seeded From UniProt

complete

involved_in

GO:0035095

behavioral response to nicotine

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

P

Seeded From UniProt

complete

involved_in

GO:0035094

response to nicotine

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

P

Seeded From UniProt

complete

enables

GO:0022848

acetylcholine-gated cation-selective channel activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

F

Seeded From UniProt

complete

enables

GO:0015464

acetylcholine receptor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

F

Seeded From UniProt

complete

involved_in

GO:0008542

visual learning

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

P

Seeded From UniProt

complete

involved_in

GO:0007613

memory

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

P

Seeded From UniProt

complete

involved_in

GO:0007612

learning

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

P

Seeded From UniProt

complete

part_of

GO:0005892

acetylcholine-gated channel complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

C

Seeded From UniProt

complete

involved_in

GO:0001666

response to hypoxia

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P17787
ensembl:ENSP00000357461

P

Seeded From UniProt

complete

enables

GO:0004888

transmembrane signaling receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006201

F

Seeded From UniProt

complete

enables

GO:0005216

ion channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002394
InterPro:IPR006201

F

Seeded From UniProt

complete

enables

GO:0005230

extracellular ligand-gated ion channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006202
InterPro:IPR036734

F

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002394
InterPro:IPR006029
InterPro:IPR006202
InterPro:IPR036719
InterPro:IPR036734

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002394
InterPro:IPR006029
InterPro:IPR006201
InterPro:IPR006202
InterPro:IPR036719
InterPro:IPR036734

C

Seeded From UniProt

complete

enables

GO:0022848

acetylcholine-gated cation-selective channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002394
InterPro:IPR032932

F

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006201

P

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002394

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0628
UniProtKB-SubCell:SL-0219

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

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