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MOUSE:ACHB2
Contents
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0007271 |
synaptic transmission, cholinergic |
ECO:0000314 |
P |
Figure 3 suggests that β2nAchR is critical to cholinergic signaling as DHBE, specific antagonist to β2nAchR, blocks nicotine inhibition. Other nonspecific antagonists do not block nicotine inhibition. |
complete | |||||
involved_in |
GO:2000300 |
regulation of synaptic vesicle exocytosis |
ECO:0006042 |
cell fractionation evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:2000300 |
regulation of synaptic vesicle exocytosis |
ECO:0006042 |
cell fractionation evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:2000300 |
regulation of synaptic vesicle exocytosis |
ECO:0001225 |
knockout evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:2000300 |
regulation of synaptic vesicle exocytosis |
ECO:0001225 |
knockout evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
enables |
GO:1904315 |
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential |
ECO:0006013 |
patch-clamp recording evidence used in manual assertion |
F |
|
Seeded From UniProt |
complete | ||
enables |
GO:1904315 |
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential |
ECO:0001225 |
knockout evidence used in manual assertion |
F |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0099060 |
integral component of postsynaptic specialization membrane |
ECO:0006003 |
electron microscopy evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0099056 |
integral component of presynaptic membrane |
ECO:0006042 |
cell fractionation evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0099056 |
integral component of presynaptic membrane |
ECO:0000279 |
western blot evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0098981 |
cholinergic synapse |
ECO:0006013 |
patch-clamp recording evidence used in manual assertion |
C |
part_of:(UBERON:0002240) |
Seeded From UniProt |
complete | ||
part_of |
GO:0098981 |
cholinergic synapse |
ECO:0006003 |
electron microscopy evidence used in manual assertion |
C |
part_of:(UBERON:0001989) |
Seeded From UniProt |
complete | ||
part_of |
GO:0098981 |
cholinergic synapse |
ECO:0001225 |
knockout evidence used in manual assertion |
C |
part_of:(UBERON:0002240) |
Seeded From UniProt |
complete | ||
part_of |
GO:0098691 |
dopaminergic synapse |
ECO:0006042 |
cell fractionation evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0098691 |
dopaminergic synapse |
ECO:0006042 |
cell fractionation evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0098691 |
dopaminergic synapse |
ECO:0001225 |
knockout evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0098691 |
dopaminergic synapse |
ECO:0001225 |
knockout evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0050877 |
nervous system process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:87888 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0045202 |
synapse |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:95747 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043005 |
neuron projection |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:95747 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042391 |
regulation of membrane potential |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:87885 |
P |
Seeded From UniProt |
complete | ||
contributes_to |
GO:0042166 |
acetylcholine binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:87890 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035094 |
response to nicotine |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:87891 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034220 |
ion transmembrane transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:95613 |
P |
Seeded From UniProt |
complete | ||
contributes_to |
GO:0015464 |
acetylcholine receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001825425 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007274 |
neuromuscular synaptic transmission |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001825425 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007271 |
synaptic transmission, cholinergic |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:87887 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007268 |
chemical synaptic transmission |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003011 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007165 |
signal transduction |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000434994 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005892 |
acetylcholine-gated channel complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:106213 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1861899 |
C |
Seeded From UniProt |
complete | ||
contributes_to |
GO:0005230 |
extracellular ligand-gated ion channel activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000434994 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1905144 |
response to acetylcholine |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:1904315 |
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0099060 |
integral component of postsynaptic specialization membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0099056 |
integral component of presynaptic membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0098981 |
cholinergic synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0095500 |
acetylcholine receptor signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0095500 |
acetylcholine receptor signaling pathway |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0060084 |
synaptic transmission involved in micturition |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87892 |
P |
occurs_in:(EMAPA:18321) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0051963 |
regulation of synapse assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2158714 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0051899 |
membrane depolarization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0051291 |
protein heterooligomerization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0050890 |
cognition |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0050877 |
nervous system process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0048814 |
regulation of dendrite morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2158714 |
P |
|
Seeded From UniProt |
complete | |
enables |
GO:0046982 |
protein heterodimerization activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0045759 |
negative regulation of action potential |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0045471 |
response to ethanol |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2158714 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0045188 |
regulation of circadian sleep/wake cycle, non-REM sleep |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
regulates_o_has_participant:(EMAPA:16894) |
Seeded From UniProt |
complete | |
part_of |
GO:0044853 |
plasma membrane raft |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0042391 |
regulation of membrane potential |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87888 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0042391 |
regulation of membrane potential |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87888 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0042391 |
regulation of membrane potential |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87892 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0042391 |
regulation of membrane potential |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0042320 |
regulation of circadian sleep/wake cycle, REM sleep |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
regulates_o_has_participant:(EMAPA:16894) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0042220 |
response to cocaine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042166 |
acetylcholine binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042166 |
acetylcholine binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0042113 |
B cell activation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0042113 |
B cell activation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0042053 |
regulation of dopamine metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
regulates_o_occurs_in:(EMAPA:17549) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0035176 |
social behavior |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035095 |
behavioral response to nicotine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035095 |
behavioral response to nicotine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035095 |
behavioral response to nicotine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035095 |
behavioral response to nicotine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035095 |
behavioral response to nicotine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035095 |
behavioral response to nicotine |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0035094 |
response to nicotine |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:99779 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035094 |
response to nicotine |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87888 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035094 |
response to nicotine |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87892 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035094 |
response to nicotine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035094 |
response to nicotine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2158714 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035094 |
response to nicotine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
has_participant:(EMAPA:16894) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0035094 |
response to nicotine |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0035094 |
response to nicotine |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0035094 |
response to nicotine |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0033603 |
positive regulation of dopamine secretion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0033603 |
positive regulation of dopamine secretion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0032226 |
positive regulation of synaptic transmission, dopaminergic |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0032225 |
regulation of synaptic transmission, dopaminergic |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0030890 |
positive regulation of B cell proliferation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:88336 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0030890 |
positive regulation of B cell proliferation |
ECO:0000305 |
curator inference used in manual assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0022848 |
acetylcholine-gated cation-selective channel activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87888 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0022848 |
acetylcholine-gated cation-selective channel activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87888 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0022848 |
acetylcholine-gated cation-selective channel activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
F |
|
Seeded From UniProt |
complete | |
enables |
GO:0022848 |
acetylcholine-gated cation-selective channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
occurs_in:(EMAPA:16894) |
Seeded From UniProt |
complete | ||
enables |
GO:0022848 |
acetylcholine-gated cation-selective channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
occurs_in:(EMAPA:35485)|occurs_in:(EMAPA:32789)|occurs_in:(EMAPA:19095) |
Seeded From UniProt |
complete | ||
enables |
GO:0022848 |
acetylcholine-gated cation-selective channel activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0022848 |
acetylcholine-gated cation-selective channel activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0021955 |
central nervous system neuron axonogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2158714 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0021952 |
central nervous system projection neuron axonogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2158714 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0021952 |
central nervous system projection neuron axonogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0021952 |
central nervous system projection neuron axonogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0021771 |
lateral geniculate nucleus development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2158714 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0021631 |
optic nerve morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2158714 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0021631 |
optic nerve morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0021562 |
vestibulocochlear nerve development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
results_in_development_of:(EMAPA:17572) |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019233 |
sensory perception of pain |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926251 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0016020 |
membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0015464 |
acetylcholine receptor activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0014059 |
regulation of dopamine secretion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
|
Seeded From UniProt |
complete | |
part_of |
GO:0009897 |
external side of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0008542 |
visual learning |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0008542 |
visual learning |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0008542 |
visual learning |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0008306 |
associative learning |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:99779 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008144 |
drug binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007626 |
locomotory behavior |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007613 |
memory |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007613 |
memory |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0007612 |
learning |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007612 |
learning |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0007605 |
sensory perception of sound |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_participant:(EMAPA:17572) |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007601 |
visual perception |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007601 |
visual perception |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007271 |
synaptic transmission, cholinergic |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007165 |
signal transduction |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006939 |
smooth muscle contraction |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87892 |
P |
occurs_in:(EMAPA:35448) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0006816 |
calcium ion transport |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87888 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005892 |
acetylcholine-gated channel complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005892 |
acetylcholine-gated channel complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:17549) |
Seeded From UniProt |
complete | ||
part_of |
GO:0005892 |
acetylcholine-gated channel complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005892 |
acetylcholine-gated channel complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2350 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0001666 |
response to hypoxia |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0001666 |
response to hypoxia |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0001661 |
conditioned taste aversion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0001508 |
action potential |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:87892 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0001508 |
action potential |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1926253 |
P |
|
Seeded From UniProt |
complete | |
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:1904315 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:1904315 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060078 |
regulation of postsynaptic membrane potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:1904315 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060079 |
excitatory postsynaptic potential |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060079 |
excitatory postsynaptic potential |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060079 |
excitatory postsynaptic potential |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060079 |
excitatory postsynaptic potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060079 |
excitatory postsynaptic potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060079 |
excitatory postsynaptic potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060079 |
excitatory postsynaptic potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060079 |
excitatory postsynaptic potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060079 |
excitatory postsynaptic potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060079 |
excitatory postsynaptic potential |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0022848 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1905144 |
response to acetylcholine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:1904315 |
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0099060 |
integral component of postsynaptic specialization membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0099056 |
integral component of presynaptic membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0098981 |
cholinergic synapse |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0095500 |
acetylcholine receptor signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051291 |
protein heterooligomerization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0046982 |
protein heterodimerization activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0044853 |
plasma membrane raft |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0042166 |
acetylcholine binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035094 |
response to nicotine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0033603 |
positive regulation of dopamine secretion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0022848 |
acetylcholine-gated cation-selective channel activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0016020 |
membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0008144 |
drug binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007271 |
synaptic transmission, cholinergic |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005892 |
acetylcholine-gated channel complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P12390 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050890 |
cognition |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050877 |
nervous system process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042166 |
acetylcholine binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035095 |
behavioral response to nicotine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035094 |
response to nicotine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0022848 |
acetylcholine-gated cation-selective channel activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0015464 |
acetylcholine receptor activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0008542 |
visual learning |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007613 |
memory |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007612 |
learning |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007165 |
signal transduction |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005892 |
acetylcholine-gated channel complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001666 |
response to hypoxia |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P17787 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004888 |
transmembrane signaling receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005216 |
ion channel activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005230 |
extracellular ligand-gated ion channel activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006811 |
ion transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002394 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002394 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0022848 |
acetylcholine-gated cation-selective channel activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0034220 |
ion transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0045211 |
postsynaptic membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006811 |
ion transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0045211 |
postsynaptic membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030054 |
cell junction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Nemethova, A et al. (2013) Nicotine attenuates activation of tissue resident macrophages in the mouse stomach through the β2 nicotinic acetylcholine receptor. PLoS ONE 8 e79264 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Champtiaux, N et al. (2003) Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. J. Neurosci. 23 7820-9 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Grady, SR et al. (2001) Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum. J. Neurochem. 76 258-68 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Lamotte d'Incamps, B & Ascher, P (2013) Subunit composition and kinetics of the Renshaw cell heteromeric nicotinic receptors. Biochem. Pharmacol. 86 1114-21 PubMed GONUTS page
- ↑ 5.0 5.1 Del Signore, A et al. (2002) Dystrophin stabilizes alpha 3- but not alpha 7-containing nicotinic acetylcholine receptor subtypes at the postsynaptic apparatus in the mouse superior cervical ganglion. Neurobiol. Dis. 10 54-66 PubMed GONUTS page
- ↑ 6.0 6.1 Garção, P et al. (2014) Subsynaptic localization of nicotinic acetylcholine receptor subunits: a comparative study in the mouse and rat striatum. Neurosci. Lett. 566 106-10 PubMed GONUTS page
- ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Wu, M et al. (2015) Mechanisms of inhibition and potentiation of α4β2 nicotinic acetylcholine receptors by members of the Ly6 protein family. J. Biol. Chem. 290 24509-18 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 9.4 Xu, W et al. (1999) Multiorgan autonomic dysfunction in mice lacking the beta2 and the beta4 subunits of neuronal nicotinic acetylcholine receptors. J. Neurosci. 19 9298-305 PubMed GONUTS page
- ↑ Chandrasekaran, AR et al. (2007) Developmental homeostasis of mouse retinocollicular synapses. J. Neurosci. 27 1746-55 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 Klink, R et al. (2001) Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei. J. Neurosci. 21 1452-63 PubMed GONUTS page
- ↑ Bansal, A et al. (2000) Mice lacking specific nicotinic acetylcholine receptor subunits exhibit dramatically altered spontaneous activity patterns and reveal a limited role for retinal waves in forming ON and OFF circuits in the inner retina. J. Neurosci. 20 7672-81 PubMed GONUTS page
- ↑ 13.0 13.1 Grubb, MS & Thompson, ID (2004) Visual response properties in the dorsal lateral geniculate nucleus of mice lacking the beta2 subunit of the nicotinic acetylcholine receptor. J. Neurosci. 24 8459-69 PubMed GONUTS page
- ↑ 14.0 14.1 Wehner, JM et al. (2004) Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning. Neuroscience 129 11-24 PubMed GONUTS page
- ↑ 15.0 15.1 15.2 Léna, C et al. (2004) Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice. J. Neurosci. 24 5711-8 PubMed GONUTS page
- ↑ 16.0 16.1 16.2 16.3 Darsow, T et al. (2005) Exocytic trafficking is required for nicotine-induced up-regulation of alpha 4 beta 2 nicotinic acetylcholine receptors. J. Biol. Chem. 280 18311-20 PubMed GONUTS page
- ↑ 17.0 17.1 17.2 Karadsheh, MS et al. (2004) Functional characterization of mouse alpha4beta2 nicotinic acetylcholine receptors stably expressed in HEK293T cells. J. Neurochem. 91 1138-50 PubMed GONUTS page
- ↑ 18.0 18.1 18.2 18.3 Picciotto, MR et al. (1998) Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature 391 173-7 PubMed GONUTS page
- ↑ 19.0 19.1 Zachariou, V et al. (2001) Nicotine receptor inactivation decreases sensitivity to cocaine. Neuropsychopharmacology 24 576-89 PubMed GONUTS page
- ↑ Skok, M et al. (2006) The role of nicotinic acetylcholine receptors in lymphocyte development. J. Neuroimmunol. 171 86-98 PubMed GONUTS page
- ↑ 21.0 21.1 21.2 Skok, M et al. (2005) Nicotinic receptors regulate B lymphocyte activation and immune response. Eur. J. Pharmacol. 517 246-51 PubMed GONUTS page
- ↑ 22.0 22.1 22.2 Granon, S et al. (2003) Executive and social behaviors under nicotinic receptor regulation. Proc. Natl. Acad. Sci. U.S.A. 100 9596-601 PubMed GONUTS page
- ↑ 23.0 23.1 23.2 Besson, M et al. (2007) Long-term effects of chronic nicotine exposure on brain nicotinic receptors. Proc. Natl. Acad. Sci. U.S.A. 104 8155-60 PubMed GONUTS page
- ↑ Villégier, AS et al. (2006) Irreversible blockade of monoamine oxidases reveals the critical role of 5-HT transmission in locomotor response induced by nicotine in mice. Eur. J. Neurosci. 24 1359-65 PubMed GONUTS page
- ↑ 25.0 25.1 King, SL et al. (2004) Beta2-subunit-containing nicotinic acetylcholine receptors are critical for dopamine-dependent locomotor activation following repeated nicotine administration. Neuropharmacology 47 Suppl 1 132-9 PubMed GONUTS page
- ↑ 26.0 26.1 Shoaib, M et al. (2002) The role of nicotinic receptor beta-2 subunits in nicotine discrimination and conditioned taste aversion. Neuropharmacology 42 530-9 PubMed GONUTS page
- ↑ 27.0 27.1 27.2 Marubio, LM et al. (1999) Reduced antinociception in mice lacking neuronal nicotinic receptor subunits. Nature 398 805-10 PubMed GONUTS page
- ↑ Mameli-Engvall, M et al. (2006) Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors. Neuron 50 911-21 PubMed GONUTS page
- ↑ Zoli, M et al. (1998) Identification of four classes of brain nicotinic receptors using beta2 mutant mice. J. Neurosci. 18 4461-72 PubMed GONUTS page
- ↑ 30.0 30.1 30.2 Muir-Robinson, G et al. (2002) Retinogeniculate axons undergo eye-specific segregation in the absence of eye-specific layers. J. Neurosci. 22 5259-64 PubMed GONUTS page
- ↑ Torborg, CL et al. (2005) High frequency, synchronized bursting drives eye-specific segregation of retinogeniculate projections. Nat. Neurosci. 8 72-8 PubMed GONUTS page
- ↑ Grubb, MS et al. (2003) Abnormal functional organization in the dorsal lateral geniculate nucleus of mice lacking the beta 2 subunit of the nicotinic acetylcholine receptor. Neuron 40 1161-72 PubMed GONUTS page
- ↑ 33.0 33.1 33.2 Rossi, FM et al. (2001) Requirement of the nicotinic acetylcholine receptor beta 2 subunit for the anatomical and functional development of the visual system. Proc. Natl. Acad. Sci. U.S.A. 98 6453-8 PubMed GONUTS page
- ↑ 34.0 34.1 Bao, J et al. (2005) Requirement of nicotinic acetylcholine receptor subunit beta2 in the maintenance of spiral ganglion neurons during aging. J. Neurosci. 25 3041-5 PubMed GONUTS page
- ↑ Zoli, M et al. (1999) Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors. EMBO J. 18 1235-44 PubMed GONUTS page
- ↑ Marubio, LM & Paylor, R (2004) Impaired passive avoidance learning in mice lacking central neuronal nicotinic acetylcholine receptors. Neuroscience 129 575-82 PubMed GONUTS page
- ↑ Picciotto, MR et al. (1995) Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature 374 65-7 PubMed GONUTS page
- ↑ Caldarone, BJ et al. (2000) Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain. Neuropharmacology 39 2779-84 PubMed GONUTS page
- ↑ Rezvani, K et al. (2009) UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors. J. Neurosci. 29 6883-96 PubMed GONUTS page
- ↑ Dauger, S et al. (2004) Control of breathing in newborn mice lacking the beta-2 nAChR subunit. Acta Physiol. Scand. 182 205-12 PubMed GONUTS page
a
- GO:0022848 ! acetylcholine-gated monoatomic cation-selective channel activity
- GO:0042166 ! acetylcholine binding
- GO:0005892 ! acetylcholine-gated channel complex
- GO:0015464 ! acetylcholine receptor activity
- GO:0095500 ! acetylcholine receptor signaling pathway
- GO:0001508 ! action potential
- GO:0008306 ! associative learning
c
- GO:0006816 ! calcium ion transport
- GO:0030054 ! cell junction
- GO:0021955 ! central nervous system neuron axonogenesis
- GO:0021952 ! central nervous system projection neuron axonogenesis
- GO:0007268 ! chemical synaptic transmission
- GO:0098981 ! cholinergic synapse
- Chordata
- GO:0050890 ! cognition
- GO:0001661 ! conditioned taste aversion
- Craniata
e
g
l
m
n
o
p
- GO:0005886 ! plasma membrane
- GO:0044853 ! plasma membrane raft
- GO:0030890 ! positive regulation of B cell proliferation
- GO:0033603 ! positive regulation of dopamine secretion
- GO:0032226 ! positive regulation of synaptic transmission, dopaminergic
- GO:0045211 ! postsynaptic membrane
- GO:0051291 ! protein heterooligomerization
- GO:0046982 ! protein heterodimerization activity
r
- GO:0060078 ! regulation of postsynaptic membrane potential
- GO:0045188 ! regulation of circadian sleep/wake cycle, non-REM sleep
- GO:2000300 ! regulation of synaptic vesicle exocytosis
- GO:0048814 ! regulation of dendrite morphogenesis
- GO:0051963 ! regulation of synapse assembly
- GO:0042320 ! regulation of circadian sleep/wake cycle, REM sleep
- GO:0042391 ! regulation of membrane potential
- GO:0042053 ! regulation of dopamine metabolic process
- GO:0014059 ! regulation of dopamine secretion
- GO:0032225 ! regulation of synaptic transmission, dopaminergic
- GO:1905144 ! response to acetylcholine
- GO:0035094 ! response to nicotine
- GO:0045471 ! response to ethanol
- GO:0042220 ! response to cocaine
- GO:0001666 ! response to hypoxia
- Rodentia
s
- Sciurognathi
- GO:0019233 ! sensory perception of pain
- GO:0007605 ! sensory perception of sound
- GO:0007165 ! signal transduction
- GO:0006939 ! smooth muscle contraction
- GO:0035176 ! social behavior
- GO:0045202 ! synapse
- GO:0007271 ! synaptic transmission, cholinergic
- GO:0060084 ! synaptic transmission involved in micturition
t