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MOUSE:ANTR2

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Antxr2
Protein Name(s) Anthrax toxin receptor 2
External Links
UniProt Q6DFX2
EMBL BC003908
BC076595
CCDS CCDS39177.1
RefSeq NP_598499.1
UniGene Mm.24842
ProteinModelPortal Q6DFX2
SMR Q6DFX2
PhosphoSite Q6DFX2
MaxQB Q6DFX2
PaxDb Q6DFX2
PRIDE Q6DFX2
Ensembl ENSMUST00000031281
GeneID 71914
KEGG mmu:71914
UCSC uc008yga.1
CTD 118429
MGI MGI:1919164
eggNOG NOG41216
GeneTree ENSGT00430000031214
HOGENOM HOG000264249
HOVERGEN HBG050514
InParanoid Q6DFX2
OMA TATECSN
OrthoDB EOG7XWPN7
PhylomeDB Q6DFX2
TreeFam TF328943
ChiTaRS Antxr2
NextBio 334938
PRO PR:Q6DFX2
Proteomes UP000000589
Bgee Q6DFX2
CleanEx MM_ANTXR2
ExpressionAtlas Q6DFX2
Genevestigator Q6DFX2
GO GO:0009986
GO:0009897
GO:0016021
GO:0046872
GO:0004872
GO:0022414
GO:1901998
Gene3D 3.40.50.410
InterPro IPR017360
IPR008399
IPR008400
IPR002035
Pfam PF05586
PF05587
PF00092
PIRSF PIRSF038023
ProDom PD377005
SMART SM00327
SUPFAM SSF53300
PROSITE PS50234

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1901998

toxin transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1919164
PANTHER:PTN001042739

P

Seeded From UniProt

complete

involved_in

GO:1901998

toxin transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1919164
PANTHER:PTN000412082

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1919164
PANTHER:PTN001042739
UniProtKB:Q9H6X2

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001042739
ZFIN:ZDB-GENE-060526-14

C

Seeded From UniProt

complete

enables

GO:0004888

transmembrane signaling receptor activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001042739
UniProtKB:Q9H6X2

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1901998

toxin transport

PMID:23716698[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0022414

reproductive process

PMID:19617532[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:4352944

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

PMID:19617532[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:23716698[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0009897

external side of plasma membrane

PMID:23716698[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008399
InterPro:IPR008400
InterPro:IPR017360

C

Seeded From UniProt

complete

enables

GO:0038023

signaling receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008399
InterPro:IPR008400
InterPro:IPR017360

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 Slater, LH et al. (2013) CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc. Natl. Acad. Sci. U.S.A. 110 9932-7 PubMed GONUTS page
  3. 3.0 3.1 Liu, S et al. (2009) Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo. Proc. Natl. Acad. Sci. U.S.A. 106 12424-9 PubMed GONUTS page