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HUMAN:CALCR
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | CALCR | |
Protein Name(s) | Calcitonin receptor
CT-R | |
External Links | ||
UniProt | P30988 | |
EMBL | L00587 X69920 U26553 U26554 X82466 S77876 S77875 AB022177 AB022178 AJ831406 AJ831407 FN994995 FN994996 AY430048 AK313996 AC003078 AC005024 CH236949 CH471091 BC069611 BC075028 | |
CCDS | CCDS55125.1 CCDS5631.1 | |
PIR | I37217 S34486 | |
RefSeq | NP_001158209.1 NP_001158210.1 NP_001733.1 | |
UniGene | Hs.489127 | |
ProteinModelPortal | P30988 | |
SMR | P30988 | |
BioGrid | 107250 | |
IntAct | P30988 | |
MINT | MINT-1217503 | |
STRING | 9606.ENSP00000352561 | |
BindingDB | P30988 | |
ChEMBL | CHEMBL2111189 | |
DrugBank | DB01278 DB00017 | |
GuidetoPHARMACOLOGY | 43 | |
TCDB | 9.A.14.4.1 | |
PhosphoSite | P30988 | |
DMDM | 550544247 | |
PaxDb | P30988 | |
PRIDE | P30988 | |
Ensembl | ENST00000394441 ENST00000415529 ENST00000423724 ENST00000426151 | |
GeneID | 799 | |
KEGG | hsa:799 | |
UCSC | uc003umv.2 | |
CTD | 799 | |
GeneCards | GC07M093053 | |
H-InvDB | HIX0033513 | |
HGNC | HGNC:1440 | |
HPA | HPA028962 | |
MIM | 114131 | |
neXtProt | NX_P30988 | |
PharmGKB | PA26032 | |
eggNOG | NOG255868 | |
GeneTree | ENSGT00760000118800 | |
HOGENOM | HOG000230695 | |
HOVERGEN | HBG102129 | |
InParanoid | P30988 | |
KO | K04576 | |
OrthoDB | EOG712TW2 | |
TreeFam | TF315710 | |
Reactome | REACT_18290 REACT_19327 | |
ChiTaRS | CALCR | |
GeneWiki | Calcitonin_receptor | |
GenomeRNAi | 799 | |
NextBio | 3248 | |
PRO | PR:P30988 | |
Proteomes | UP000005640 | |
Bgee | P30988 | |
CleanEx | HS_CALCR | |
ExpressionAtlas | P30988 | |
Genevestigator | P30988 | |
GO | GO:0016021 GO:0005887 GO:0005886 GO:0032841 GO:0004948 GO:0008565 GO:0004872 GO:0007189 GO:0007186 GO:0045762 GO:0030819 GO:0007204 GO:0072659 GO:0015031 GO:0031623 GO:0051384 | |
InterPro | IPR003287 IPR017981 IPR001688 IPR001879 IPR000832 IPR017983 | |
Pfam | PF00002 PF02793 | |
PRINTS | PR00361 PR01350 PR00249 | |
SMART | SM00008 | |
PROSITE | PS00649 PS00650 PS50227 PS50261 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
part_of |
GO:0150058 |
amylin receptor complex 3 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0150057 |
amylin receptor complex 2 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0001540 |
amyloid-beta binding |
ECO:0000305 |
curator inference used in manual assertion |
GO:1904645 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:1904645 |
response to amyloid-beta |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0038041 |
cross-receptor inhibition within G protein-coupled receptor heterodimer |
ECO:0000353 |
physical interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0097643 |
amylin receptor activity |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0097647 |
amylin receptor signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0097647 |
amylin receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0097647 |
amylin receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60895,UniProtKB:P12969:PRO_0000004122 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097647 |
amylin receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0097647 |
amylin receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60894,UniProtKB:P12969:PRO_0000004122 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097647 |
amylin receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60894,UniProtKB:P10997:PRO_0000004106 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097647 |
amylin receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0097647 |
amylin receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ComplexPortal:CPX-2173 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60895,UniProtKB:P12969:PRO_0000004122 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60894,UniProtKB:P12969:PRO_0000004122 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60894,UniProtKB:P10997:PRO_0000004106 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010942 |
positive regulation of cell death |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106 |
P |
regulates_expression_of:(ENSEMBL:ENSG00000170345) |
Seeded From UniProt |
complete | |
involved_in |
GO:0010942 |
positive regulation of cell death |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ComplexPortal:CPX-1134,UniProtKB:O60896 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097647 |
amylin receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ComplexPortal:CPX-1134,UniProtKB:O60896 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097647 |
amylin receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106 |
P |
Seeded From UniProt |
complete | ||
contributes_to |
GO:0097643 |
amylin receptor activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60894,UniProtKB:P06881 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010628 |
positive regulation of gene expression |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106 |
P |
regulates_expression_of:(ENSEMBL:ENSG00000170345) |
Seeded From UniProt |
complete | |
involved_in |
GO:0051897 |
positive regulation of protein kinase B signaling |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ComplexPortal:CPX-1134,UniProtKB:O60896 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051897 |
positive regulation of protein kinase B signaling |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P05067:PRO_0000000092 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010739 |
positive regulation of protein kinase A signaling |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106 |
P |
has_regulation_target:(UniProtKB:P13861) |
Seeded From UniProt |
complete | |
involved_in |
GO:0033138 |
positive regulation of peptidyl-serine phosphorylation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106 |
P |
has_regulation_target:(UniProtKB:P13861) |
Seeded From UniProt |
complete | |
involved_in |
GO:0033138 |
positive regulation of peptidyl-serine phosphorylation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ComplexPortal:CPX-1134,UniProtKB:O60896 |
P |
has_regulation_target:(UniProtKB:P13861) |
Seeded From UniProt |
complete | |
involved_in |
GO:1905665 |
positive regulation of calcium ion import across plasma membrane |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ComplexPortal:CPX-1134,UniProtKB:O60896 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1905665 |
positive regulation of calcium ion import across plasma membrane |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P12969:PRO_0000004122 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ComplexPortal:CPX-1134,UniProtKB:O60896 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0150056 |
amylin receptor complex 1 |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051384 |
response to glucocorticoid |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0032841 |
calcitonin binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0032841 |
calcitonin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
NOT|enables |
GO:0032841 |
calcitonin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
NOT|involved_in |
GO:0007190 |
activation of adenylate cyclase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007189 |
adenylate cyclase-activating G protein-coupled receptor signaling pathway |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0001635 |
calcitonin gene-related peptide receptor activity |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
contributes_to |
GO:0097643 |
amylin receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001381030 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0030424 |
axon |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001381030 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007204 |
positive regulation of cytosolic calcium ion concentration |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101950 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004948 |
calcitonin receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101950 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004888 |
transmembrane signaling receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000832 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004948 |
calcitonin receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007166 |
cell surface receptor signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001688 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045762 |
positive regulation of adenylate cyclase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045762 |
positive regulation of adenylate cyclase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0032841 |
calcitonin binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0032841 |
calcitonin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
NOT|involved_in |
GO:0007202 |
activation of phospholipase C activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004948 |
calcitonin receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004948 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045762 |
positive regulation of adenylate cyclase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0032841 |
calcitonin binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0032841 |
calcitonin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007204 |
positive regulation of cytosolic calcium ion concentration |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005623 |
cell |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0007204 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045762 |
positive regulation of adenylate cyclase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0032841 |
calcitonin binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004948 |
calcitonin receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004948 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
Reactome:R-HSA-388396 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-HSA-744887 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007165 |
signal transduction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 1.28 1.29 1.30 1.31 1.32 1.33 1.34 1.35 Fu, W et al. (2012) Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways. J. Biol. Chem. 287 18820-30 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Kuwasako, K et al. (2004) Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins. Mol. Pharmacol. 65 207-13 PubMed GONUTS page
- ↑ Wada, S et al. (2001) Regulation of calcitonin receptor by glucocorticoid in human osteoclast-like cells prepared in vitro using receptor activator of nuclear factor-kappaB ligand and macrophage colony-stimulating factor. Endocrinology 142 1471-8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Beaudreuil, J et al. (2004) Molecular characterization of two novel isoforms of the human calcitonin receptor. Gene 343 143-51 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Kuestner, RE et al. (1994) Cloning and characterization of an abundant subtype of the human calcitonin receptor. Mol. Pharmacol. 46 246-55 PubMed GONUTS page
- ↑ 6.0 6.1 Egerton, M et al. (1995) Identification of multiple human calcitonin receptor isoforms: heterologous expression and pharmacological characterization. J. Mol. Endocrinol. 14 179-89 PubMed GONUTS page
- ↑ Gorn, AH et al. (1992) Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line. J. Clin. Invest. 90 1726-35 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 8.6 Albrandt, K et al. (1995) Molecular cloning and functional expression of a third isoform of the human calcitonin receptor and partial characterization of the calcitonin receptor gene. Endocrinology 136 5377-84 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 Gorn, AH et al. (1995) Expression of two human skeletal calcitonin receptor isoforms cloned from a giant cell tumor of bone. The first intracellular domain modulates ligand binding and signal transduction. J. Clin. Invest. 95 2680-91 PubMed GONUTS page
- ↑ Blattner, RJ (1967) Hemolytic anemia associated with Wilson's disease. J. Pediatr. 71 284-7 PubMed GONUTS page
a
- GO:0007190 ! activation of adenylate cyclase activity
- GO:0007189 ! adenylate cyclase-activating G protein-coupled receptor signaling pathway
- GO:0150058 ! amylin receptor complex 3
- GO:0150056 ! amylin receptor complex 1
- GO:0150057 ! amylin receptor complex 2
- GO:0097643 ! amylin receptor activity
- GO:0097647 ! amylin receptor signaling pathway
- GO:0001540 ! amyloid-beta binding
- GO:0030424 ! axon
c
- GO:0032841 ! calcitonin binding
- GO:0001635 ! calcitonin gene-related peptide receptor activity
- GO:0004948 ! calcitonin receptor activity
- Catarrhini
- GO:0007166 ! cell surface receptor signaling pathway
- Chordata
- Craniata
- GO:0038041 ! cross-receptor inhibition within G protein-coupled receptor heterodimer
g
o
p
- GO:0005886 ! plasma membrane
- GO:0033138 ! positive regulation of peptidyl-serine phosphorylation
- GO:0010739 ! positive regulation of protein kinase A signaling
- GO:0070374 ! positive regulation of ERK1 and ERK2 cascade
- GO:0051897 ! positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
- GO:0010628 ! positive regulation of gene expression
- GO:0045762 ! positive regulation of adenylate cyclase activity
- GO:1905665 ! positive regulation of calcium ion import across plasma membrane
- GO:0007204 ! positive regulation of cytosolic calcium ion concentration
- Primates