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HUMAN:CD5
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | CD5 (synonyms: LEU1) | |
| Protein Name(s) | T-cell surface glycoprotein CD5
Lymphocyte antigen T1/Leu-1 | |
| External Links | ||
| UniProt | P06127 | |
| EMBL | X04391 X89405 AJ237927 AJ237928 AJ237929 AJ237930 AJ237931 AJ237932 EF064752 AK292698 AP000437 BC027901 | |
| CCDS | CCDS8000.1 | |
| PIR | A26396 | |
| RefSeq | NP_055022.2 | |
| UniGene | Hs.58685 | |
| PDB | 2JA4 2JOP 2JP0 2OTT | |
| PDBsum | 2JA4 2JOP 2JP0 2OTT | |
| ProteinModelPortal | P06127 | |
| SMR | P06127 | |
| BioGrid | 107359 | |
| DIP | DIP-21N | |
| IntAct | P06127 | |
| MINT | MINT-4656212 | |
| STRING | 9606.ENSP00000342681 | |
| PhosphoSite | P06127 | |
| UniCarbKB | P06127 | |
| DMDM | 313104090 | |
| MaxQB | P06127 | |
| PaxDb | P06127 | |
| PRIDE | P06127 | |
| DNASU | 921 | |
| Ensembl | ENST00000347785 | |
| GeneID | 921 | |
| KEGG | hsa:921 | |
| UCSC | uc009ynk.3 | |
| CTD | 921 | |
| GeneCards | GC11P060869 | |
| H-InvDB | HIX0009680 | |
| HGNC | HGNC:1685 | |
| HPA | CAB015392 CAB020308 | |
| MIM | 153340 | |
| neXtProt | NX_P06127 | |
| PharmGKB | PA26224 | |
| eggNOG | NOG86650 | |
| GeneTree | ENSGT00390000017536 | |
| HOGENOM | HOG000111490 | |
| HOVERGEN | HBG005286 | |
| InParanoid | P06127 | |
| KO | K06455 | |
| OMA | MSFHRNH | |
| OrthoDB | EOG7TF792 | |
| PhylomeDB | P06127 | |
| TreeFam | TF329295 | |
| EvolutionaryTrace | P06127 | |
| GeneWiki | CD5_(protein) | |
| GenomeRNAi | 921 | |
| NextBio | 3810 | |
| PRO | PR:P06127 | |
| Proteomes | UP000005640 | |
| Bgee | P06127 | |
| CleanEx | HS_CD5 | |
| ExpressionAtlas | P06127 | |
| Genevestigator | P06127 | |
| GO | GO:0009897 GO:0005887 GO:0005886 GO:0004872 GO:0005044 GO:0004888 GO:0097190 GO:0008283 GO:0008037 GO:0031295 | |
| Gene3D | 3.10.250.10 | |
| InterPro | IPR001190 IPR017448 IPR003566 | |
| Pfam | PF00530 | |
| PRINTS | PR00258 PR01409 | |
| SMART | SM00202 | |
| SUPFAM | SSF56487 | |
| PROSITE | PS50287 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0008283 |
cell population proliferation |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008037 |
cell recognition |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004888 |
transmembrane signaling receptor activity |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0038023 |
signaling receptor activity |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031295 |
T cell costimulation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88340 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002499882 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016192 |
vesicle-mediated transport |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005044 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0097190 |
apoptotic signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P13379 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0031295 |
T cell costimulation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P13379 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0009897 |
external side of plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P13379 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005044 |
scavenger receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001190 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Jones, NH et al. () Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/Leu-1. Nature 323 346-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Van de Velde, H et al. (1991) The B-cell surface protein CD72/Lyb-2 is the ligand for CD5. Nature 351 662-5 PubMed GONUTS page
- ↑ 3.0 3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Kirchgessner, H et al. (2001) The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain. J. Exp. Med. 193 1269-84 PubMed GONUTS page
