GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Category:GO:0005044 ! scavenger receptor activity

Jump to: navigation, search

DAG for GO:0005044id: GO:0005044

name: scavenger receptor activity
namespace: molecular_function
def: "Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs)." [GOC:bf, PMID:11790542, PMID:12379907, PMID:12621157, PMID:20981357]
comment: Note that many gene products that are called scavenger receptors have a broad range of potential ligands and also can be annotated to 'pattern recognition receptor activity ; GO:0038187' or its child terms, or to 'lipoprotein receptor activity ; GO:0030228' or its child terms. For receptors that transduce a signal rather than endocytose their ligand, consider instead the terms 'signaling receptor activity ; GO:0038023' and its children.
subset: goslim_chembl
synonym: "macrophage receptor activity" NARROW []
is_a: GO:0038024 ! cargo receptor activity

AmiGO <GOterm>GO:0005044</GOterm>
Gene Ontology Home

The contents of this box are automatically generated. You can help by adding information to the "Notes"

Usage Notes


See Help:References for how to manage references in GONUTS.