Category:GO:0038024 ! cargo receptor activity

name: cargo receptor activity
namespace: molecular_function
def: "Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span membranes (for instance the plasma membrane or the endoplasmic reticulum membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit the cargo molecules to nascent vesicles." [PMID:15239958, PMID:27903609]
comment: Notes: (1) For receptors binding a molecule but coupled to a signal transduction pathway, consider instead the term 'signaling receptor activity ; GO:0038023' and its children. (2) Cargo receptors transport substances by vesicular transport, not by transmembrane transport. For transmembrane transporters, consider instead the term 'transmembrane transporter activity ; GO:0022857'.
subset: goslim_drosophila
subset: goslim_generic
synonym: "endocytic receptor activity" NARROW [GOC:signaling, ISBN:0123645387, PMID:12671190]
synonym: "receptor activity" BROAD []
synonym: "receptor activity involved in receptor-mediated endocytosis" NARROW [GOC:bf]
synonym: "transport receptor activity" BROAD [GOC:signaling]
is_a: GO:0003674 ! molecular_function
relationship: has_part: GO:0060090 ! molecular adaptor activity
relationship: part_of: GO:0016192 ! vesicle-mediated transport

AmiGO <GOterm>GO:0038024</GOterm>
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