MOUSE:LEUK

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Spn
Protein Name(s)	Leukosialin B-cell differentiation antigen LP-3 Leukocyte sialoglycoprotein Lymphocyte antigen 48 Ly-48 Sialophorin
External Links
UniProt	P15702
EMBL	X17018 X52609 S70677 M30693
CCDS	CCDS21858.1
PIR	A43545
RefSeq	NP_001032899.1 NP_033285.1 XP_006507585.1
UniGene	Mm.283714
PDB	2EMS
PDBsum	2EMS
ProteinModelPortal	P15702
SMR	P15702
STRING	10090.ENSMUSP00000049534
iPTMnet	P15702
PhosphoSitePlus	P15702
EPD	P15702
PaxDb	P15702
PeptideAtlas	P15702
PRIDE	P15702
Ensembl	ENSMUST00000049931 ENSMUST00000143713
GeneID	20737
KEGG	mmu:20737
UCSC	uc009juh.2
CTD	6693
MGI	MGI:98384
eggNOG	ENOG410J161 ENOG410YXQE
GeneTree	ENSGT00390000017626
HOGENOM	HOG000294199
HOVERGEN	HBG006258
InParanoid	P15702
KO	K06477
OMA	GPPLTMA
OrthoDB	EOG091G0MEV
PhylomeDB	P15702
TreeFam	TF337688
Reactome	[www.reactome.org/content/detail/R-MMU-202733 R-MMU-202733] [www.reactome.org/content/detail/R-MMU-210991 R-MMU-210991]
EvolutionaryTrace	P15702
PRO	PR:P15702
Proteomes	UP000000589
Bgee	ENSMUSG00000051457
CleanEx	MM_SPN
ExpressionAtlas	P15702
Genevisible	P15702
GO	GO:0005604 GO:0009986 GO:0009897 GO:0070062 GO:0005615 GO:0005887 GO:0016020 GO:0001931 GO:0097190 GO:0007166 GO:0042742 GO:0007162 GO:0050868 GO:0042130 GO:0001808 GO:0045060 GO:0001934 GO:0042102 GO:0042535 GO:0050688 GO:0050776 GO:0001562 GO:0031295

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0001931	uropod	PMID:24250818^[1]	ECO:0000314			C		Organism: Homo Sapiens Protein: Leukosialin Figure 4 B) PKCθ regulates MTOC and CD43 localization to uropods	complete CACAO 12495
part_of	GO:0005902	microvillus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P13838	C		Seeded From UniProt	complete
involved_in	GO:0032609	interferon-gamma production	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16150	P		Seeded From UniProt	complete
involved_in	GO:0002296	T-helper 1 cell lineage commitment	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P16150	P		Seeded From UniProt	complete
involved_in	GO:2000404	regulation of T cell migration	PMID:21289089^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0001931	uropod	PMID:21289089^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0050901	leukocyte tethering or rolling	PMID:26700769^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042130	negative regulation of T cell proliferation	PMID:17638845^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:2000406	positive regulation of T cell migration	PMID:17638845^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0031072	heat shock protein binding	PMID:20633027^[5]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:A0A0H3LCC3	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0097190	apoptotic signaling pathway	PMID:10429671^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071594	thymocyte aggregation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3750	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050868	negative regulation of T cell activation	PMID:9645617^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050852	T cell receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3750	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050776	regulation of immune response	PMID:9645617^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050776	regulation of immune response	PMID:7566153^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050688	regulation of defense response to virus	PMID:7566153^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045060	negative thymic T cell selection	PMID:10429671^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042742	defense response to bacterium	PMID:10899905^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042742	defense response to bacterium	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16150	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	PMID:10899905^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16150	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042130	negative regulation of T cell proliferation	PMID:9645617^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042130	negative regulation of T cell proliferation	PMID:7566153^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042130	negative regulation of T cell proliferation	PMID:15117976^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042102	positive regulation of T cell proliferation	PMID:7790813^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042102	positive regulation of T cell proliferation	PMID:11380685^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032609	interferon-gamma production	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16150	P		Seeded From UniProt	complete
part_of	GO:0032154	cleavage furrow	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3750	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031295	T cell costimulation	PMID:7790813^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031295	T cell costimulation	PMID:11380685^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031295	T cell costimulation	PMID:10429671^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0031072	heat shock protein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16150	F		Seeded From UniProt	complete
enables	GO:0030544	Hsp70 protein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16150	F		Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3750	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3750	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010468	regulation of gene expression	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3750	P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16150	C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3750	C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:9645617^[7]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:8920854^[13]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000826)\|part_of:(CL:0000817)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:7795661^[14]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000236)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:7790813^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:7566153^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:7514104^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:7477353^[16]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:32760) part_of:(CL:0000236)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:15843532^[17]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:15117976^[10]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:14635057^[18]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000624)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:11728336^[19]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:11380685^[12]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000542)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:10943842^[20]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16332) part_of:(CL:0000081)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007166	cell surface receptor signaling pathway	PMID:7790813^[11]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0000084)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007162	negative regulation of cell adhesion	PMID:7566153^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007162	negative regulation of cell adhesion	PMID:11828253^[21]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007162	negative regulation of cell adhesion	PMID:11937524^[22]	ECO:0000314	direct assay evidence used in manual assertion		P	regulates_o_has_participant:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0005902	microvillus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3750	C		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:11937524^[22]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:11728336^[19]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16150	C		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	PMID:7514104^[15]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:28251)\|part_of:(EMAPA:32689)\|part_of:(EMAPA:29917)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002296	T-helper 1 cell lineage commitment	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P16150	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001934	positive regulation of protein phosphorylation	PMID:20360400^[23]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1314872	P	regulates_o_has_input:(MGI:MGI:103036)	Seeded From UniProt	complete
part_of	GO:0001931	uropod	PMID:11937524^[22]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0001931	uropod	PMID:11728336^[19]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001808	negative regulation of type IV hypersensitivity	PMID:9645617^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001562	response to protozoan	PMID:11994475^[24]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004888	transmembrane signaling receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR038829	F		Seeded From UniProt	complete
involved_in	GO:0032609	interferon-gamma production	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR038829	P		Seeded From UniProt	complete
involved_in	GO:0050863	regulation of T cell activation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR038829	P		Seeded From UniProt	complete
involved_in	GO:2000404	regulation of T cell migration	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR038829	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C		Seeded From UniProt	complete
part_of	GO:0016605	PML body	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0465	C		Seeded From UniProt	complete
part_of	GO:0005902	microvillus	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0293	C		Seeded From UniProt	complete
part_of	GO:0001931	uropod	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0141	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Cannon, JL et al. (2013) PKCθ regulates T cell motility via ezrin-radixin-moesin localization to the uropod. PLoS ONE 8 e78940 PubMed GONUTS page
↑ ^2.0 ^2.1 Cannon, JL et al. (2011) CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation. Mol. Biol. Cell 22 954-63 PubMed GONUTS page
↑ Velázquez, F et al. (2016) CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo. J. Immunol. 196 1305-1316 PubMed GONUTS page
↑ ^4.0 ^4.1 Mody, PD et al. (2007) Signaling through CD43 regulates CD4 T-cell trafficking. Blood 110 2974-82 PubMed GONUTS page
↑ Hickey, TB et al. (2010) Mycobacterium tuberculosis employs Cpn60.2 as an adhesin that binds CD43 on the macrophage surface. Cell. Microbiol. 12 1634-47 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Kishimoto, H & Sprent, J (1999) Several different cell surface molecules control negative selection of medullary thymocytes. J. Exp. Med. 190 65-73 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 Thurman, EC et al. (1998) Regulation of in vitro and in vivo T cell activation by CD43. Int. Immunol. 10 691-701 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 Manjunath, N et al. (1995) Negative regulation of T-cell adhesion and activation by CD43. Nature 377 535-8 PubMed GONUTS page
↑ ^9.0 ^9.1 Fratazzi, C et al. (2000) A macrophage invasion mechanism for mycobacteria implicating the extracellular domain of CD43. J. Exp. Med. 192 183-92 PubMed GONUTS page
↑ ^10.0 ^10.1 Tong, J et al. (2004) CD43 regulation of T cell activation is not through steric inhibition of T cell-APC interactions but through an intracellular mechanism. J. Exp. Med. 199 1277-83 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 Sperling, AI et al. (1995) CD43 is a murine T cell costimulatory receptor that functions independently of CD28. J. Exp. Med. 182 139-46 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 Bagriacik, EU et al. (2001) CD43 potentiates CD3-induced proliferation of murine intestinal intraepithelial lymphocytes. Immunol. Cell Biol. 79 303-7 PubMed GONUTS page
↑ Chappel, MS et al. (1996) Cross-linking the murine heat-stable antigen induces apoptosis in B cell precursors and suppresses the anti-CD40-induced proliferation of mature resting B lymphocytes. J. Exp. Med. 184 1639-49 PubMed GONUTS page
↑ Wenger, RH et al. (1995) B-cell maturation in chimaeric mice deficient for the heat stable antigen (HSA/mouse CD24). Transgenic Res. 4 173-83 PubMed GONUTS page
↑ ^15.0 ^15.1 Shiota, J et al. (1994) A unique murine CD43 epitope Lp-3: distinct distribution from another CD43 epitope S7. Cell. Immunol. 155 402-13 PubMed GONUTS page
↑ Cheng, AM et al. (1995) Syk tyrosine kinase required for mouse viability and B-cell development. Nature 378 303-6 PubMed GONUTS page
↑ Cheung, H et al. (2005) Accessory protein-like is essential for IL-18-mediated signaling. J. Immunol. 174 5351-7 PubMed GONUTS page
↑ Garcia, GG & Miller, RA (2003) Age-related defects in CD4+ T cell activation reversed by glycoprotein endopeptidase. Eur. J. Immunol. 33 3464-72 PubMed GONUTS page
↑ ^19.0 ^19.1 ^19.2 Allenspach, EJ et al. (2001) ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse. Immunity 15 739-50 PubMed GONUTS page
↑ Tamura, K et al. (2000) Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102 221-31 PubMed GONUTS page
↑ Fuzii, HT & Travassos, LR (2002) Transient resistance to B16F10 melanoma growth and metastasis in CD43-/- mice. Melanoma Res. 12 9-16 PubMed GONUTS page
↑ ^22.0 ^22.1 ^22.2 Savage, ND et al. (2002) Polar redistribution of the sialoglycoprotein CD43: implications for T cell function. J. Immunol. 168 3740-6 PubMed GONUTS page
↑ Tsuruyama, T et al. (2010) Dual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lymphoblastic lymphomas. J. Leukoc. Biol. 88 107-16 PubMed GONUTS page
↑ Todeschini, AR et al. (2002) Costimulation of host T lymphocytes by a trypanosomal trans-sialidase: involvement of CD43 signaling. J. Immunol. 168 5192-8 PubMed GONUTS page

[PMID:24250818-1] Cannon, JL et al. (2013) PKCθ regulates T cell motility via ezrin-radixin-moesin localization to the uropod. PLoS ONE 8 e78940 PubMed GONUTS page

[PMID:21289089-2] 2.0 ^2.1 Cannon, JL et al. (2011) CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation. Mol. Biol. Cell 22 954-63 PubMed GONUTS page

[PMID:26700769-3] Velázquez, F et al. (2016) CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo. J. Immunol. 196 1305-1316 PubMed GONUTS page

[PMID:17638845-4] 4.0 ^4.1 Mody, PD et al. (2007) Signaling through CD43 regulates CD4 T-cell trafficking. Blood 110 2974-82 PubMed GONUTS page

[PMID:20633027-5] Hickey, TB et al. (2010) Mycobacterium tuberculosis employs Cpn60.2 as an adhesin that binds CD43 on the macrophage surface. Cell. Microbiol. 12 1634-47 PubMed GONUTS page

[PMID:10429671-6] 6.0 ^6.1 ^6.2 Kishimoto, H & Sprent, J (1999) Several different cell surface molecules control negative selection of medullary thymocytes. J. Exp. Med. 190 65-73 PubMed GONUTS page

[PMID:9645617-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 Thurman, EC et al. (1998) Regulation of in vitro and in vivo T cell activation by CD43. Int. Immunol. 10 691-701 PubMed GONUTS page

[PMID:7566153-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 Manjunath, N et al. (1995) Negative regulation of T-cell adhesion and activation by CD43. Nature 377 535-8 PubMed GONUTS page

[PMID:10899905-9] 9.0 ^9.1 Fratazzi, C et al. (2000) A macrophage invasion mechanism for mycobacteria implicating the extracellular domain of CD43. J. Exp. Med. 192 183-92 PubMed GONUTS page

[PMID:15117976-10] 10.0 ^10.1 Tong, J et al. (2004) CD43 regulation of T cell activation is not through steric inhibition of T cell-APC interactions but through an intracellular mechanism. J. Exp. Med. 199 1277-83 PubMed GONUTS page

[PMID:7790813-11] 11.0 ^11.1 ^11.2 ^11.3 Sperling, AI et al. (1995) CD43 is a murine T cell costimulatory receptor that functions independently of CD28. J. Exp. Med. 182 139-46 PubMed GONUTS page

[PMID:11380685-12] 12.0 ^12.1 ^12.2 Bagriacik, EU et al. (2001) CD43 potentiates CD3-induced proliferation of murine intestinal intraepithelial lymphocytes. Immunol. Cell Biol. 79 303-7 PubMed GONUTS page

[PMID:8920854-13] Chappel, MS et al. (1996) Cross-linking the murine heat-stable antigen induces apoptosis in B cell precursors and suppresses the anti-CD40-induced proliferation of mature resting B lymphocytes. J. Exp. Med. 184 1639-49 PubMed GONUTS page

[PMID:7795661-14] Wenger, RH et al. (1995) B-cell maturation in chimaeric mice deficient for the heat stable antigen (HSA/mouse CD24). Transgenic Res. 4 173-83 PubMed GONUTS page

[PMID:7514104-15] 15.0 ^15.1 Shiota, J et al. (1994) A unique murine CD43 epitope Lp-3: distinct distribution from another CD43 epitope S7. Cell. Immunol. 155 402-13 PubMed GONUTS page

[PMID:7477353-16] Cheng, AM et al. (1995) Syk tyrosine kinase required for mouse viability and B-cell development. Nature 378 303-6 PubMed GONUTS page

[PMID:15843532-17] Cheung, H et al. (2005) Accessory protein-like is essential for IL-18-mediated signaling. J. Immunol. 174 5351-7 PubMed GONUTS page

[PMID:14635057-18] Garcia, GG & Miller, RA (2003) Age-related defects in CD4+ T cell activation reversed by glycoprotein endopeptidase. Eur. J. Immunol. 33 3464-72 PubMed GONUTS page

[PMID:11728336-19] 19.0 ^19.1 ^19.2 Allenspach, EJ et al. (2001) ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse. Immunity 15 739-50 PubMed GONUTS page

[PMID:10943842-20] Tamura, K et al. (2000) Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102 221-31 PubMed GONUTS page

[PMID:11828253-21] Fuzii, HT & Travassos, LR (2002) Transient resistance to B16F10 melanoma growth and metastasis in CD43-/- mice. Melanoma Res. 12 9-16 PubMed GONUTS page

[PMID:11937524-22] 22.0 ^22.1 ^22.2 Savage, ND et al. (2002) Polar redistribution of the sialoglycoprotein CD43: implications for T cell function. J. Immunol. 168 3740-6 PubMed GONUTS page

[PMID:20360400-23] Tsuruyama, T et al. (2010) Dual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lymphoblastic lymphomas. J. Leukoc. Biol. 88 107-16 PubMed GONUTS page

[PMID:11994475-24] Todeschini, AR et al. (2002) Costimulation of host T lymphocytes by a trypanosomal trans-sialidase: involvement of CD43 signaling. J. Immunol. 168 5192-8 PubMed GONUTS page

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