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Category:GO:0050901 ! leukocyte tethering or rolling
name: leukocyte tethering or rolling
namespace: biological_process
def: "Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection)." [GOC:bf, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538, Wikipedia:Leukocyte_extravasation]
is_a: GO:0061756 ! leukocyte adhesion to vascular endothelial cell
relationship: part_of: GO:0045123 ! cellular extravasation
AmiGO
<GOterm>GO:0050901</GOterm>
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