Have any questions? Please email us at ecoliwiki@gmail.com

Category:GO:0050901 ! leukocyte tethering or rolling

Jump to: navigation, search
DAG for GO:0050901id: GO:0050901

name: leukocyte tethering or rolling
namespace: biological_process
def: "Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection)." [GOC:bf, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538, Wikipedia:Leukocyte_extravasation]
is_a: GO:0061756 ! leukocyte adhesion to vascular endothelial cell
relationship: part_of: GO:0045123 ! cellular extravasation


Last version checked

23:02:2017 10:01.

Last updated

Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"

Usage Notes


See Help:References for how to manage references in GONUTS.

Child Terms

This category has the following 2 subcategories, out of 2 total.

Pages in category "GO:0050901 ! leukocyte tethering or rolling"

The following 20 pages are in this category, out of 20 total.

Jump to pages starting with: C H M P