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Category:GO:0004222 ! metalloendopeptidase activity

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DAG for GO:0004222id: GO:0004222

name: metalloendopeptidase activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE]
synonym: "metalloendoprotease activity" NARROW [GOC:mah]
synonym: "metalloendoproteinase activity" NARROW [GOC:mah]
xref: EC:3.4.24.-
is_a: GO:0004175 ! endopeptidase activity
is_a: GO:0008237 ! metallopeptidase activity

AmiGO <GOterm>GO:0004222</GOterm>
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Pages in category "GO:0004222 ! metalloendopeptidase activity"

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