GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

CLOBO:Q08077

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Clostridium botulinum. (1491)
Gene Name(s) bont/b (ECO:0000313 with EMBL:CAA50482.1)
Protein Name(s) BoNT/B (ECO:0000313 with EMBL:CAA50482.1)
External Links
UniProt Q08077
EMBL X71343
PIR I40631
ProteinModelPortal Q08077
SMR Q08077
GO GO:0005576
GO:0004222
GO:0008270
GO:0051609
GO:0009405
Gene3D 2.60.120.200
3.90.1240.10
InterPro IPR000395
IPR013320
IPR011065
IPR013104
IPR012928
IPR012500
Pfam PF01742
PF07951
PF07953
PF07952
PRINTS PR00760
SUPFAM SSF49899
SSF50386

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004175

endopeptidase activity

PMID:20693440[1]

ECO:0000314

F

Figure 3 shows the endopeptidase activities of Bont/b. Cleavage of VAMPtide was measured when exposed to various forms of the protein.

complete

involved_in

GO:0071806

protein transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008320

P

Seeded From UniProt

complete

enables

GO:0004222

metalloendopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000395

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012928

C

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000395

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000395

F

Seeded From UniProt

complete

enables

GO:0008320

protein transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012500

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012500
InterPro:IPR012928

P

Seeded From UniProt

complete

involved_in

GO:0046929

negative regulation of neurotransmitter secretion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000395
InterPro:IPR012500
InterPro:IPR012928
InterPro:IPR013104

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Wang, HH et al. (2010) Endopeptidase activities of botulinum neurotoxin type B complex, holotoxin, and light chain. Appl. Environ. Microbiol. 76 6658-63 PubMed GONUTS page