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HORSE:F7AYK2

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Species (Taxon ID) Equus caballus (Horse). (9796)
Gene Name(s) MMP2 (ECO:0000313 with VGNC:VGNC:20229)
Protein Name(s) Matrix metallopeptidase 2 (ECO:0000313 with Ensembl:ENSECAP00000002955)
External Links
UniProt F7AYK2
STRING 9796.ENSECAP00000002955
MEROPS M10.003
PaxDb F7AYK2
Ensembl ENSECAT00000004278
VGNC VGNC:20229
eggNOG KOG1565
ENOG410XQ5D
GeneTree ENSGT00910000144034
InParanoid F7AYK2
OMA HESCTSA
OrthoDB EOG091G03DP
TreeFam TF315428
Proteomes UP000002281
Bgee ENSECAG00000000953
GO GO:0031012
GO:0005615
GO:0005739
GO:0005886
GO:0030017
GO:0004222
GO:0008270
GO:0001955
GO:0060346
GO:0071230
GO:0030574
GO:0007566
GO:0035987
GO:0060325
GO:0001957
GO:0045089
GO:1904707
GO:0001666
CDD cd00062
cd00094
cd04278
Gene3D 1.10.101.10
2.10.10.10
2.110.10.10
3.40.390.10
InterPro IPR028708
IPR000562
IPR036943
IPR000585
IPR036375
IPR018487
IPR018486
IPR013806
IPR033739
IPR024079
IPR001818
IPR021190
IPR021158
IPR006026
IPR002477
IPR036366
PANTHER PTHR10201:SF29
Pfam PF00040
PF00045
PF00413
PF01471
PIRSF PIRSF001191
PRINTS PR00138
SMART SM00059
SM00120
SM00235
SUPFAM SSF50923
SSF57440
PROSITE PS00546
PS00023
PS51092
PS00024
PS51642

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0048771

tissue remodeling

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002565602
RGD:621316

P

Seeded From UniProt

complete

involved_in

GO:0030574

collagen catabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101900
MGI:MGI:1276107
MGI:MGI:1340026
MGI:MGI:97008
MGI:MGI:97009
MGI:MGI:97011
PANTHER:PTN001303987
RGD:621316
RGD:621320
UniProtKB:P45452

P

Seeded From UniProt

complete

involved_in

GO:0030198

extracellular matrix organization

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0033438
FB:FBgn0035049
MGI:MGI:1340026
MGI:MGI:1353466
MGI:MGI:97008
MGI:MGI:97011
PANTHER:PTN001303987
UniProtKB:P45452
WB:WBGene00006987
ZFIN:ZDB-GENE-040426-2132

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97005
MGI:MGI:97009
PANTHER:PTN000810753
RGD:3100
RGD:620196
RGD:621316
RGD:621317
RGD:621320
RGD:631408
UniProtKB:B5DFD5
UniProtKB:P02790
UniProtKB:P08253
UniProtKB:P14780
UniProtKB:P22894
UniProtKB:P39900
UniProtKB:P50281
UniProtKB:Q90611

C

Seeded From UniProt

complete

enables

GO:0004222

metalloendopeptidase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0033438
MGI:MGI:101900
MGI:MGI:1340026
MGI:MGI:1341867
MGI:MGI:97009
MGI:MGI:97011
PANTHER:PTN001303987
RGD:620196
TAIR:locus:2020548
TAIR:locus:2025891
TAIR:locus:2032467
TAIR:locus:2055605
TAIR:locus:2130928
UniProtKB:O60882
UniProtKB:O75900
UniProtKB:P03956
UniProtKB:P14780
UniProtKB:P39900
UniProtKB:P45452
UniProtKB:P51512
UniProtKB:Q90611
UniProtKB:Q99542

F

Seeded From UniProt

complete

involved_in

GO:0001666

response to hypoxia

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97009
PANTHER:PTN002565602
RGD:621316

P

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001818
InterPro:IPR006026
InterPro:IPR021158
InterPro:IPR021190
InterPro:IPR028708

P

Seeded From UniProt

complete

enables

GO:0008237

metallopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006026
InterPro:IPR024079
InterPro:IPR033739

F

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001818
InterPro:IPR006026
InterPro:IPR021158
InterPro:IPR021190
InterPro:IPR033739

F

Seeded From UniProt

complete

part_of

GO:0031012

extracellular matrix

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001818
InterPro:IPR021158
InterPro:IPR021190

C

Seeded From UniProt

complete

enables

GO:0004222

metalloendopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001818
InterPro:IPR021158
InterPro:IPR021190
InterPro:IPR028708

F

Seeded From UniProt

complete

enables

GO:0008237

metallopeptidase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0482

F

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

Scavenger Hunt Item: #28

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page