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CANFA:E7AIM5
Contents
| Species (Taxon ID) | Canis familiaris (Dog) (Canis lupus familiaris). (9615) | |
| Gene Name(s) | adam9 (ECO:0000313 with EMBL:CBV37339.1) | |
| Protein Name(s) | Disintegrin and metalloproteinase domain 9,transcript variant 3 (ECO:0000313 with EMBL:CBV37339.1) | |
| External Links | ||
| UniProt | E7AIM5 | |
| EMBL | FR667708 | |
| UniGene | Cfa.32687 | |
| ProteinModelPortal | E7AIM5 | |
| MEROPS | M12.209 | |
| GO | GO:0005576 GO:0004222 GO:0008270 GO:0007229 | |
| Gene3D | 3.40.390.10 4.10.70.10 | |
| InterPro | IPR006586 IPR001762 IPR018358 IPR024079 IPR001590 IPR002870 | |
| Pfam | PF08516 PF00200 PF01562 PF01421 | |
| SMART | SM00050 | |
| SUPFAM | SSF57552 | |
| PROSITE | PS50215 PS00427 PS50214 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0050908 |
detection of light stimulus involved in visual perception |
ECO:0000315 |
P |
Figure 3: Establishes ADAM9 mutation in dogs affected with crd3 in this study. Figure 4: ADAM9 mutation is crd3 affected dogs causes a frame shift mutation resulting in a premature stop codon at base 6 of exon 17. Figure 1:By 15 months of age ERG dysfunction is detected as reduced 30Hz flicker cone responses in dogs affected with crd3 due to ADAM9 mutation, and at later ages by continued deterioration of cone and rod responses in these affected dogs. |
complete | |||||
|
enables |
GO:0004222 |
metalloendopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008237 |
metallopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007229 |
integrin-mediated signaling pathway |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Goldstein, O et al. (2010) An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9. Mol. Vis. 16 1549-69 PubMed GONUTS page
