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RAT:MMP7
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Mmp7 (synonyms: Mmp-7) | |
| Protein Name(s) | Matrilysin
Matrin Matrix metalloproteinase-7 MMP-7 Pump-1 protease Uterine metalloproteinase | |
| External Links | ||
| UniProt | P50280 | |
| EMBL | L24374 BC064657 | |
| PIR | A57490 | |
| RefSeq | NP_036996.1 | |
| UniGene | Rn.10282 | |
| ProteinModelPortal | P50280 | |
| SMR | P50280 | |
| STRING | 10116.ENSRNOP00000014041 | |
| MEROPS | M10.008 | |
| PRIDE | P50280 | |
| Ensembl | ENSRNOT00000014041 | |
| GeneID | 25335 | |
| KEGG | rno:25335 | |
| UCSC | RGD:3100 | |
| CTD | 4316 | |
| RGD | 3100 | |
| eggNOG | NOG312228 | |
| GeneTree | ENSGT00760000118870 | |
| HOGENOM | HOG000239471 | |
| HOVERGEN | HBG052484 | |
| InParanoid | P50280 | |
| KO | K01397 | |
| OMA | KRFYSYD | |
| OrthoDB | EOG7XPZ57 | |
| PhylomeDB | P50280 | |
| TreeFam | TF315428 | |
| BRENDA | 3.4.24.23 | |
| Reactome | REACT_198590 REACT_199129 REACT_199177 REACT_199178 | |
| NextBio | 606227 | |
| PRO | PR:P50280 | |
| Proteomes | UP000002494 | |
| Genevestigator | P50280 | |
| GO | GO:0070062 GO:0005578 GO:0004222 GO:0008270 GO:0002779 GO:0030574 GO:0050829 GO:0050830 GO:0042127 GO:0042493 | |
| Gene3D | 3.40.390.10 | |
| InterPro | IPR028707 IPR024079 IPR001818 IPR021190 IPR021158 IPR006026 IPR002477 | |
| PANTHER | PTHR10201:SF128 | |
| Pfam | PF00413 PF01471 | |
| PRINTS | PR00138 | |
| SMART | SM00235 | |
| SUPFAM | SSF47090 | |
| PROSITE | PS00546 PS00142 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0071260 |
cellular response to mechanical stimulus |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060135 |
maternal process involved in female pregnancy |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044849 |
estrous cycle |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031667 |
response to nutrient levels |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008201 |
heparin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007568 |
aging |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030574 |
collagen catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101900 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030198 |
extracellular matrix organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0033438 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97005 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004222 |
metalloendopeptidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0033438 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008237 |
metallopeptidase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P09237 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P09237 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004222 |
metalloendopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001818 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001818 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008237 |
metallopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001818 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031012 |
extracellular matrix |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030574 |
collagen catabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008237 |
metallopeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Yerrapureddy, A et al. (2010) Cyclic stretch magnitude and duration affect rat alveolar epithelial gene expression. Cell. Physiol. Biochem. 25 113-22 PubMed GONUTS page
- ↑ Rechtman, MP et al. (1999) Effect of inhibition of matrix metalloproteinases on endometrial decidualization and implantation in mated rats. J. Reprod. Fertil. 117 169-77 PubMed GONUTS page
- ↑ Feng, J et al. (1998) Matrilysin activity in the rat uterus during the oestrous cycle and implantation. J. Reprod. Fertil. 114 347-50 PubMed GONUTS page
- ↑ 4.0 4.1 Chen, G et al. (2007) Increased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction. Am. J. Physiol. Renal Physiol. 293 F1272-81 PubMed GONUTS page
- ↑ 5.0 5.1 Yu, WH & Woessner, JF Jr (2000) Heparan sulfate proteoglycans as extracellular docking molecules for matrilysin (matrix metalloproteinase 7). J. Biol. Chem. 275 4183-91 PubMed GONUTS page
- ↑ Yuan, Q et al. (2012) [Influence of Bushen Huoxue decoction on beta-catenin, MMP-7 of synoviocytes in rats with knee osteoarthritis]. Zhongguo Gu Shang 25 761-5 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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