ECOBD:C5W9C5

Species (Taxon ID)	Escherichia coli (strain B / BL21-DE3). (469008)
Gene Name(s)	No Information Provided. (synonyms: hflB (ECO:0000313 with EMBL:ACT44847.1))
Protein Name(s)	ATP-dependent zinc metalloprotease FtsH (ECO:0000256 with HAMAP-Rule:MF_01458)
External Links
UniProt	C5W9C5
EMBL	CP001509 AM946981
RefSeq	YP_003000752.1 YP_003055618.1
ProteinModelPortal	C5W9C5
SMR	C5W9C5
EnsemblBacteria	ACT44847 CAQ33511
GeneID	8113130 8179941
KEGG	ebe:B21_02994 ebl:ECD_03043
eggNOG	COG0465
HOGENOM	HOG000217276
KO	K03798
Proteomes	UP000001509 UP000009074
GO	GO:0016021 GO:0005886 GO:0005524 GO:0016887 GO:0004222 GO:0008270 GO:0030163
Gene3D	3.40.50.300
HAMAP	MF_01458
InterPro	IPR003593 IPR003959 IPR003960 IPR005936 IPR027417 IPR011546 IPR000642
Pfam	PF00004 PF06480 PF01434
SMART	SM00382
SUPFAM	SSF52540
TIGRFAMs	TIGR01241
PROSITE	PS00674

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0006508	proteolysis	PMID:10809689	IDA: Inferred from Direct Assay		P	Figure 4 demonstrates proteolysis of β-casein by FtsH.	complete
	GO:0006508	proteolysis	PMID:9712851	IDA: Inferred from Direct Assay		P	Figure 2 shows in vivo degradation of the λCII protein	complete
	GO:0016021	integral to membrane	PMID:9712851	IDA: Inferred from Direct Assay		C	Figure 5 shows impaired FtsH-FtsH interaction by a periplasmic deletion.	complete
	GO:0000166	nucleotide binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003593	F	Seeded From UniProt	complete
	GO:0000166	nucleotide binding	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
	GO:0004222	metalloendopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000642 InterPro:IPR005936 InterPro:IPR011546	F	Seeded From UniProt	complete
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000642 InterPro:IPR003959 InterPro:IPR003960 InterPro:IPR011546	F	Seeded From UniProt	complete
	GO:0005524	ATP binding	GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_01458	F	Seeded From UniProt	complete
	GO:0005524	ATP binding	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
	GO:0005886	plasma membrane	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0997	C	Seeded From UniProt	complete
	GO:0005886	plasma membrane	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-1003	C	Seeded From UniProt	complete
	GO:0005886	plasma membrane	GO_REF:0000040	IEA: Inferred from Electronic Annotation	UniProtKB-SubCell:SL-0037	C	Seeded From UniProt	complete
	GO:0006200	obsolete ATP catabolic process	GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_01458	P	Seeded From UniProt	complete
	GO:0006508	proteolysis	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000642	P	Seeded From UniProt	complete
	GO:0006508	proteolysis	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0645	P	Seeded From UniProt	complete
	GO:0008233	peptidase activity	GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_01458	F	Seeded From UniProt	complete
	GO:0008233	peptidase activity	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0645	F	Seeded From UniProt	complete
	GO:0008237	metallopeptidase activity	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0482	F	Seeded From UniProt	complete
	GO:0008270	zinc ion binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011546	F	Seeded From UniProt	complete
	GO:0008270	zinc ion binding	GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_01458	F	Seeded From UniProt	complete
	GO:0016020	membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005936	C	Seeded From UniProt	complete
	GO:0016020	membrane	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
	GO:0016021	integral component of membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011546	C	Seeded From UniProt	complete
	GO:0016021	integral component of membrane	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
	GO:0016787	hydrolase activity	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
	GO:0016887	ATPase activity	GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_01458	F	Seeded From UniProt	complete
	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003593	F	Seeded From UniProt	complete
	GO:0030163	protein catabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005936	P	Seeded From UniProt	complete
	GO:0030163	protein catabolic process	GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_01458	P	Seeded From UniProt	complete
	GO:0046872	metal ion binding	GO_REF:0000038	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
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References

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