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ECOLI:MEPM
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | mepM (synonyms: yebA) | |
| Protein Name(s) | Murein DD-endopeptidase MepM
Murein hydrolase MepM ORFU | |
| External Links | ||
| UniProt | P0AFS9 | |
| EMBL | U00096 AP009048 U38702 M77039 | |
| RefSeq | NP_416370.2 WP_001184045.1 | |
| ProteinModelPortal | P0AFS9 | |
| SMR | P0AFS9 | |
| BioGrid | 4260352 | |
| STRING | 511145.b1856 | |
| MEROPS | M23.011 | |
| PaxDb | P0AFS9 | |
| EnsemblBacteria | AAC74926 BAA15664 | |
| GeneID | 946376 | |
| KEGG | ecj:JW5304 eco:b1856 | |
| PATRIC | 32119035 | |
| EchoBASE | EB0013 | |
| EcoGene | EG10013 | |
| eggNOG | ENOG4105DR5 COG0739 | |
| HOGENOM | HOG000281149 | |
| InParanoid | P0AFS9 | |
| KO | K19304 | |
| OMA | EYQTVYM | |
| OrthoDB | EOG61KBD1 | |
| PhylomeDB | P0AFS9 | |
| BioCyc | EcoCyc:EG10013-MONOMER ECOL316407:JW5304-MONOMER MetaCyc:EG10013-MONOMER | |
| UniPathway | UPA00963 | |
| PRO | PR:P0AFS9 | |
| Proteomes | UP000000318 UP000000625 | |
| GO | GO:0016021 GO:0005886 GO:0004175 GO:0046872 GO:0004222 GO:0001896 GO:0045227 GO:0000920 GO:0071555 GO:0000270 | |
| Gene3D | 3.10.350.10 | |
| InterPro | IPR011055 IPR018392 IPR013731 IPR016047 | |
| Pfam | PF01476 PF08525 PF01551 | |
| SMART | SM00257 | |
| SUPFAM | SSF51261 SSF54106 | |
| PROSITE | PS51782 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0009254 |
peptidoglycan turnover |
ECO:0000315 |
P |
Fig 4, Fig 3, Fig 5 C & D, Fig 6 |
complete | |||||
| GO:0004175 |
endopeptidase activity |
ECO:0000314 |
F |
Fig 4 |
complete | |||||
| GO:0004175 |
endopeptidase activity |
ECO:0000314 |
F |
Fig 4 |
complete | |||||
|
enables |
GO:0004175 |
endopeptidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004222 |
metalloendopeptidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10013 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001896 |
autolysis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10013 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000920 |
septum digestion after cytokinesis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10013 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001896 |
autolysis |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000920 |
septum digestion after cytokinesis |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000920 |
septum digestion after cytokinesis |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004222 |
metalloendopeptidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000270 |
peptidoglycan metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071555 |
cell wall organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-1003 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008237 |
metallopeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045227 |
capsule polysaccharide biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00963 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Singh, SK et al. (2012) Three redundant murein endopeptidases catalyse an essential cleavage step in peptidoglycan synthesis of Escherichia coli K12. Mol. Microbiol. 86 1036-51 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Uehara, T et al. (2009) LytM-domain factors are required for daughter cell separation and rapid ampicillin-induced lysis in Escherichia coli. J. Bacteriol. 191 5094-107 PubMed GONUTS page
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